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Findings enlarge the spectrum of tubulinopathies and emphasize that mutations of TUBB6 should be considered in patients with congenital non-progressive facial palsy.
TUBB6 is an inhibitor of pyroptosis.
Data indicate that leucine-rich repeat kinase 2 (LRRK2) selectively interacts with three beta-tubulin isoforms: TUBB, TUBB4, and TUBB6.
betaV-tubulin (show TUBB Proteins) expression is a potentially promising prognostic marker of malignancy.
in colorectal cancer patients, there was a link between poor survival, the expression of TUBB3 (show TUBB3 Proteins)/TUBB6, and androgen receptor (show AR Proteins) only in females
The TUBB6 expression was largely decreased in most tumors.
The results provide the first evidence that a specific isoform of beta-tubulin (show TUBB Proteins) is required for mitosis.[beta5 tubulin (show TUBB Proteins)]
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
tubulin, beta 6
, tubulin beta-6 chain-like
, beta tubulin6
, tubulin beta-6 chain
, beta-tubulin class-VI
, tubulin, beta 3
, class V beta-tubulin
, tubulin beta MGC4083
, tubulin beta class V