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anti-Human Tubulin A Antibodies:
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Data show that retinal endothelial cells (HREC) treated with low molecular weight fraction of commercial 5% human serum albumin (show ALB Antibodies) (LMWF5A) exhibit a rapid increase in the amount and distribution of acetylated alpha-tubulin (show TUBA4A Antibodies).
The C-terminal tail from the tubulin beta (show TUBB Antibodies) I isotype, but not the beta III isotype, formed contacts in the putative binding site of a recently discovered antineoplastic peptide that disrupts microtubule formation in glioma cells.
TUBA1B (show TUBA1B Antibodies)/ESR1 (show ESR1 Antibodies) gene interaction might play pivotal roles in the occurrence and development of Postmenopausal Osteoporosis.
Taken together our data provide valuable information regarding the interaction of CK1delta and a-tubulin (show TUBB Antibodies) and a novel approach for the development of pharmacological tools to inhibit proliferation of cancer cells.
Results suggest that lithium chloride (LiCl) treatments activate alpha-tubulin N-acetyltransferase 1 (alphaTAT1) by the inhibition of glycogen synthase kinase 3 beta (GSK-3beta (show GSK3b Antibodies)) and promote the alpha-tubulin (show TUBA4A Antibodies) acetylation, and then elongate the primary cilia.
NAD-dependent regulation of alpha-tubulin (show TUBA4A Antibodies) acetylation is mediated by SIRT2 (show SIRT2 Antibodies).
Data indicate that the derivatives exhibited much better potency to inhibit tubulin (show TUBB Antibodies) polymerization but a decreased activity to inhibit Hsp27 (show HSPB1 Antibodies) chaperone function.
Increased TUBA1B (show TUBA1B Antibodies) expression is associated with poor overall survival in hepatocellular carcinoma.
ARHGAP21 (show ARHGAP21 Antibodies) is a Rho-GAP (show ARHGAP36 Antibodies) involved in cell-cell junction remodeling that affects migration and EMT (show ITK Antibodies) through alpha-tubulin (show TUBA4A Antibodies) interaction and acetylation
TQ induced a concentration- and time-dependent degradation of alpha/beta tubulin (show TUBB Antibodies) in both cancer cell types.
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
, alpha-tubulin ubiquitous
, tubulin K-alpha-1
, tubulin alpha-1B chain
, tubulin alpha-ubiquitous chain
, tubulin, alpha, ubiquitous