anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) Antibodies

6 Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) Antibodies from 2 manufacturers are available on www.antibodies-online.com.

Data Quality
  • 5
Type
  • 6
    Primary antibodies
Antigen
  • 6
Reactivity
  • 5
  • 1
Application
  • 5
  • 5
  • 1
  • 1
  • 1
Host
  • 6
Clonality
  • 6
Binding Specificity
  • 2
  • 1
  • 1
  • 1
  • 1
Isotype
  • 6
Format
  • 6
6 Products
ReactivityHuman
Application DB, ELISA
Order details Cat. No. ABIN3030641
$452.38
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN3028606
$452.38
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityMouse (Murine)
Application ELISA, WB
Order details Cat. No. ABIN3030639
$452.38
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN3030638
$452.38
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN3030640
$452.38
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application FACS, IF, IHC, WB
Order details Cat. No. ABIN2797433
ISO
$467.50
400 μL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
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Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) Antigen Profile

Protein Summary

This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene\; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, the E3 ubiquitin-protein ligase MDM2, a protein responsible for the degradation of p53. In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control. This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene.

Alternative names and synonyms associated with Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A)

  • cyclin-dependent kinase inhibitor 2A (Cdkn2a) antibody
  • cyclin-dependent kinase inhibitor 2A (LOC100731972) antibody
  • cyclin-dependent kinase inhibitor 2A (LOC100340625) antibody
  • cyclin dependent kinase inhibitor 2A (CDKN2A) antibody
  • ARF antibody
  • ARF-INK4a antibody
  • CDK4I antibody
  • CDKN2 antibody
  • CMM2 antibody
  • INK4 antibody
  • INK4A antibody
  • INK4a-ARF antibody
  • Ink4a/Arf antibody
  • MLM antibody
  • MTS-1 antibody
  • MTS1 antibody
  • P14 antibody
  • P14ARF antibody
  • P16 antibody
  • p16(INK4a) antibody
  • P16-INK4A antibody
  • p16Cdkn2a antibody
  • P16INK4 antibody
  • p16INK4a antibody
  • P19 antibody
  • p19 antibody
  • P19ARF antibody
  • Pctr1 antibody
  • TP16 antibody

Protein level used designations for CDKN2A

CDK4I , Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4) , cell cycle inhibitor , cell cycle regulator , cyclin-dependent kinase 4 inhibitor A , cyclin-dependent kinase inhibitor 2a p16Ink4a , cyclin-dependent kinase inhibitor 2a p19Arf , p16-INK4 , p16-INK4a , CDK4 inhibitor p16-INK4 , cell cycle negative regulator beta , cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) , multiple tumor suppressor 1 , cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4) , cyclin-dependent kinase inhibitor 2A, isoforms 1/2 , cyclin-dependent kinase inhibitor protein , mitochondrial smARF

GENE ID SPECIES
25163 Rattus norvegicus
100731972 Cavia porcellus
100340625 Oryctolagus cuniculus
1029 Homo sapiens
12578 Mus musculus