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anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) Antibodies

9 results:

anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) (AA 104-131), (C-Term) antibody Primary Antibody

CDKN2A Reactivity: Human FACS, IF, IHC (p), WB Host: Rabbit Polyclonal RB19093 unconjugated
Pubmed 1
Catalog No. ABIN1981278
$423.50
Plus shipping costs $45.00
400 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 10 to 11 Business Days

anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) (AA 1-30) antibody Primary Antibody

CDKN2A Reactivity: Human ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3030638
$493.63
Plus shipping costs $45.00
0.4 mL (More quantities available)
local_shipping Shipping to: United States
Delivery in 2 to 3 Business Days

anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) (AA 39-65) antibody Primary Antibody

CDKN2A Reactivity: Mouse ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3030639
$493.63
Plus shipping costs $45.00
0.4 mL (More quantities available)
local_shipping Shipping to: United States
Delivery in 2 to 3 Business Days

anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) (pSer8) antibody Primary Antibody

CDKN2A Reactivity: Human DB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3030641
$507.38
Plus shipping costs $45.00
0.4 mL (More quantities available)
local_shipping Shipping to: United States
Delivery in 2 to 3 Business Days

anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) (AA 39-65) antibody Primary Antibody

CDKN2A Reactivity: Mouse WB Host: Rabbit Polyclonal RB40175 unconjugated
Catalog No. ABIN1538376
$412.50
Plus shipping costs $45.00
400 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 10 to 11 Business Days

anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) (pSer140) antibody Primary Antibody

CDKN2A Reactivity: Human IHC (p), WB Host: Rabbit Polyclonal RB21280 unconjugated
Pubmed 1
Catalog No. ABIN6241061
$556.07
Plus shipping costs $45.00
400 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 10 to 11 Business Days

anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) (AA 1-30), (N-Term) antibody Primary Antibody

CDKN2A Reactivity: Human WB Host: Rabbit Polyclonal RB41435 unconjugated
Catalog No. ABIN6243104
$527.50
Plus shipping costs $45.00
400 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 10 to 11 Business Days

anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) (AA 145-176), (Ser152) antibody Primary Antibody

CDKN2A Reactivity: Human WB Host: Rabbit Polyclonal RB53347 unconjugated
Catalog No. ABIN6243105
$527.50
Plus shipping costs $45.00
400 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 10 to 11 Business Days

anti-Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) (pSer8) antibody Primary Antibody

CDKN2A Reactivity: Human DB Host: Rabbit Polyclonal RB41435 unconjugated
Catalog No. ABIN6241060
$541.79
Plus shipping costs $45.00
400 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 10 to 11 Business Days
  • Type Primary
    • Primary
  • Target Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A)
    • Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A)
    • Histone 3 (H3)
    • Epidermal Growth Factor Receptor (EGFR)
    • Tumor Protein P53 (TP53)
    • Mast/stem Cell Growth Factor Receptor (KIT)
    • Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
    • tau Protein
    • Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2)
    • CD4
    • Tumor Necrosis Factor alpha (TNF alpha)
    • V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
    • Estrogen Receptor 1 (ESR1)
    • Interferon gamma (IFNG)
    • Nuclear Factor-kB p65 (NFkBP65)
    • V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
    • BCL2-Associated Agonist of Cell Death (BAD)
    • Albumin (ALB)
    • B-Cell CLL/lymphoma 2 (BCL2)
    • Tuberous Sclerosis 2 (TSC2)
    • CD19 Molecule (CD19)
    • CD8a Molecule (CD8A)
    • Hemagglutinin (HA)
    • Jun Proto-Oncogene (JUN)
    • Platelet/endothelial Cell Adhesion Molecule (PECAM1)
    • Integrin alpha M (ITGAM)
    • CD3 epsilon (CD3E)
    • Myc Proto-Oncogene protein (MYC)
    • Histone H4
    • CD44
    • Interleukin 6 (IL6)
    • Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1)
    • CD8
    • Interleukin 2 Receptor, alpha (IL2RA)
    • Vimentin (VIM)
    • C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
    • VEGF Receptor 2 (VEGFR2)
    • Interleukin 2 (IL2)
    • Tuberous Sclerosis 1 (TSC1)
    • Amyloid beta (A4) Precursor Protein (APP)
    • Insulin Receptor Substrate 1 (IRS1)
    • CD5
    • Epithelial Cell Adhesion Molecule (EPCAM)
    • CD3
    • Glial Fibrillary Acidic Protein (GFAP)
    • CD34
    • Mucin 1 (MUC1)
    • PTK2 Protein tyrosine Kinase 2 (PTK2)
    • Catenin, beta (CATNB)
    • Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1)
    • Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1)
    • Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1)
  • Application
    • Western Blotting (WB)
    • ELISA
    • Dot Blot (DB)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Flow Cytometry (FACS)
    • Immunofluorescence (IF)
  • Reactivity
    • Human
    • Mouse
  • Cited in publications
  • Images available
  • Host
    • Rabbit
  • Clonality
    • Polyclonal
  • Clone
    • RB41435
    • RB19093
    • RB21280
    • RB40175
    • RB53347
  • Binding Specificity
    • AA 1-30
    • AA 39-65
    • pSer8
    • AA 104-131
    • AA 145-176
    • C-Term
    • N-Term
    • Ser152
    • pSer140
  • Isotype
    • Ig Fraction
  • Format
    • Liquid

Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A) Antigen Profile

Protein Summary

This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene\; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, the E3 ubiquitin-protein ligase MDM2, a protein responsible for the degradation of p53. In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control. This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene.

Alternative names and synonyms associated with Cyclin-Dependent Kinase Inhibitor 2A (Melanoma, P16, Inhibits CDK4) (CDKN2A)

  • cyclin-dependent kinase inhibitor 2A (Cdkn2a) antibody
  • cyclin-dependent kinase inhibitor 2A (LOC100731972) antibody
  • cyclin-dependent kinase inhibitor 2A (LOC100340625) antibody
  • cyclin dependent kinase inhibitor 2A (CDKN2A) antibody
  • ARF antibody
  • ARF-INK4a antibody
  • CDK4I antibody
  • CDKN2 antibody
  • CMM2 antibody
  • INK4 antibody
  • INK4A antibody
  • INK4a-ARF antibody
  • Ink4a/Arf antibody
  • MLM antibody
  • MTS-1 antibody
  • MTS1 antibody
  • P14 antibody
  • P14ARF antibody
  • P16 antibody
  • p16(INK4a) antibody
  • P16-INK4A antibody
  • p16Cdkn2a antibody
  • P16INK4 antibody
  • p16INK4a antibody
  • P19 antibody
  • p19 antibody
  • P19ARF antibody
  • Pctr1 antibody
  • TP16 antibody

Protein level used designations for CDKN2A

CDK4I , Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4) , cell cycle inhibitor , cell cycle regulator , cyclin-dependent kinase 4 inhibitor A , cyclin-dependent kinase inhibitor 2a p16Ink4a , cyclin-dependent kinase inhibitor 2a p19Arf , p16-INK4 , p16-INK4a , CDK4 inhibitor p16-INK4 , cell cycle negative regulator beta , cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) , multiple tumor suppressor 1 , cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4) , cyclin-dependent kinase inhibitor 2A, isoforms 1/2 , cyclin-dependent kinase inhibitor protein , mitochondrial smARF

GENE ID SPECIES
25163 Rattus norvegicus
100731972 Cavia porcellus
100340625 Oryctolagus cuniculus
1029 Homo sapiens
12578 Mus musculus

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