Browse our anti-FBXO5 (FBXO5) Antibodies

Full name:: anti-F-Box Protein 5 Antibodies (FBXO5)

On www.antibodies-online.com are 93 F-Box Protein 5 (FBXO5) Antibodies from 15 different suppliers available. Additionally we are shipping FBXO5 Kits (13) and FBXO5 Proteins (7) and many more products for this protein. A total of 116 FBXO5 products are currently listed.

Synonyms:: 2510044I10Rik, ACYPI007854, C85305, Emi1, FBX5, Fbxo5, Fbxo31, fc65h02, wu:fc65h02, wu:fe06e07, wu:fz79f03, zgc:136397, zgc:158541

list all antibodies	Gene Name	GeneID	UniProt
	FBXO5	26271	Q9UKT4
	FBXO5	67141	Q7TSG3
	FBXO5	292263
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Relevant Pathways for anti-FBXO5 Antibodies

Mitotic G1-G1/S Phases

More product categories related to FBXO5 Antibody

Top referenced anti-FBXO5 Antibodies

Dog (Canine) Polyclonal FBXO5 Primary Antibody for WB - ABIN2774700 : Estrabaud, Le Rouzic, Lopez-Vergès, Morel, Belaïdouni, Benarous, Transy, Berlioz-Torrent, Margottin-Goguet: Regulated degradation of the HIV-1 Vpu protein through a betaTrCP-independent pathway limits the release of viral particles. in PLoS pathogens 2007 (PubMed)

More Antibodies against FBXO5 Interaction Partners

Human F-Box Protein 5 (FBXO5) interaction partners

demonstration using human cell models that cell-cycle commitment is mediated by an EMI1-APC (show APC Antibodies)/C(CDH1 (show CDH1 Antibodies)) dual-negative feedback switch, in which EMI1 is both a substrate and an inhibitor of APC (show APC Antibodies)/C(CDH1 (show CDH1 Antibodies))
Both isoforms of FBXO5 promoted the migration and osteogenic differentiation potential of human periodontal ligament stem cells.
Results from a study on gene variability markers in early-stage human embryos shows that FBXO5 is a putative variability marker for the 3-day, 8-cell embryo stage.
The fact that Emi1 overexpression promotes chromosome instability (CIN) and the formation of solid cancers in vivo indicates that Emi1 overexpression actively drives solid tumorigenesis. These novel mechanistic insights have important clinical implications.
Examined eoffect of Emi1 over-expression on Skp2 expression in breast cancer. Found expression of Emi1 was positively related with Skp2 expression; Emi1 expression correlated significantly with histologic grade. Skp2 expression obtained similar results.
Human papillomavirus type 16 E7 expression causes increased EMI1 mRNA expression and also inhibits EMI1 degradation.
The C-terminal domain inhibits multiple APC/C(CDH1) functions. The intrinsically disordered D-box, linker & tail elements, & a structured Zn-binding domain synergistically block the substrate-binding site & inhibit ubiquitin-chain elongation.
Emi1 depletion enhances the sensitivity of cancer cells to doxorubicin and x-ray irradiation.
Emi1 expression (>5%) was seen in 23.3% of ovarian clear cell carcinoma, and associated with high FIGO grades and poor overall survival
Emi1 participates in human hepatocellular carcinoma (HCC (show FAM126A Antibodies)) cell proliferation and that progression is controlled by anaphase-promoting complex/cyclosome (APC (show APC Antibodies)/C) inhibition, which stabilized Skp2 and enabled p27(kip1 (show CDKN1B Antibodies)) degradation.

Zebrafish F-Box Protein 5 (FBXO5) interaction partners

These data indicate that emi1 deficiency-induced defects in vivo are due to the dysregulation of an APC/C-Cdh1 (show CDH1 Antibodies) molecular axis.
harpy/Rca1/emi1 has a role in patterning in the absence of cell division
Emi1 is a critical regulator of genomic fidelity during embryogenesis.

FBXO5 Antigen Profile

Antigen Summary

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with FBXO5

F-box protein 5 (FBXO5) antibody
F-box protein 5 (fbxo5) antibody
F-box only protein 5 (Fbxo5) antibody
F-box protein 5 (Fbxo5) antibody

2510044I10Rik antibody
ACYPI007854 antibody
C85305 antibody
Emi1 antibody
FBX5 antibody
Fbxo5 antibody
Fbxo31 antibody
fc65h02 antibody
wu:fc65h02 antibody
wu:fe06e07 antibody
wu:fz79f03 antibody
zgc:136397 antibody
zgc:158541 antibody

Protein level used designations for anti-F-Box Protein 5 (FBXO5) Antibodies

F-box only protein 5 , F-box protein Fbx5 , early mitotic inhibitor 1 , f-box only protein 31 , harpy , hrp , rca1

GENE ID	SPECIES
463083	Pan troglodytes
515080	Bos taurus
733555	Xenopus (Silurana) tropicalis
100167030	Acyrthosiphon pisum
26271	Homo sapiens
67141	Mus musculus
292263	Rattus norvegicus
612020	Canis lupus familiaris
445392	Danio rerio
101103731	Ovis aries

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Show all anti-F-Box Protein 5 (FBXO5) Antibodies with Pubmed References

Human F-Box Protein 5 (FBXO5) interaction partners

Zebrafish F-Box Protein 5 (FBXO5) interaction partners

Antigen Summary

Alternative names and synonyms associated with FBXO5

Protein level used designations for anti-F-Box Protein 5 (FBXO5) Antibodies