MCM10 Proteins

Protein Summary

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

Alternative names and synonyms associated with MCM10

• Minichromosome maintenance 10 (Mcm10) antibody
• minichromosome maintenance 10 replication initiation factor (MCM10) antibody
• minichromosome maintenance 10 replication initiation factor (Mcm10) antibody
• minichromosome maintenance 10 replication initiation factor L homeolog (mcm10.L) antibody

• 2410041F14Rik antibody
• AU018508 antibody
• C79164 antibody
• C330019M07Rik antibody
• CG9241 antibody
• Show all synonym aliases
• CNA43 antibody
• Dmel\\CG9241 antibody
• DmMCM10 antibody
• DNA43 antibody
• mcm10 antibody
• Scim19 antibody
• xmcm10 antibody

Protein level used designations for MCM10

CG9241-PA , Mcm10-PA , sensitized chromosome inheritance modifier 19 , MCM10 minichromosome maintenance deficient 10 , homolog of yeast MCM10 , hsMCM10 , protein MCM10 homolog , minichromosome maintenance deficient 10 , Mcm10p