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Browse our anti-ORC4 (ORC4) Antibodies

Full name:: anti-Origin Recognition Complex, Subunit 4 Antibodies (ORC4)

On www.antibodies-online.com are 77 Origin Recognition Complex, Subunit 4 (ORC4) Antibodies from 18 different suppliers available. Additionally we are shipping ORC4 Proteins (10) and and many more products for this protein. A total of 97 ORC4 products are currently listed.

Synonyms:: ATORC4, CG2917, Dmel\\CG2917, dmOrc4, F23H14.9, F23H14_9, fc50c03, mMmORC4, ORC, orc4, orc4l, Orc4P, origin recognition complex subunit 4, rDmORC, wu:fc50c03, zgc:85772

list all antibodies	Gene Name	GeneID	UniProt
	ORC4	5000	O43929
	ORC4	26428	O88708
	ORC4	295596	Q6P9Z8
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More product categories related to ORC4 Antibody

Top referenced anti-ORC4 Antibodies

Human Polyclonal ORC4 Primary Antibody for ELISA, WB - ABIN546717 : Todorovic, Giadrossi, Pelizon, Mendoza-Maldonado, Masai, Giacca: Human origins of DNA replication selected from a library of nascent DNA. in Molecular cell 2005 (PubMed)
Show all 3 Pubmed References
Human Polyclonal ORC4 Primary Antibody for ELISA, WB - ABIN256671 : Vashee, Simancek, Challberg, Kelly: Assembly of the human origin recognition complex. in The Journal of biological chemistry 2001 (PubMed)

More Antibodies against ORC4 Interaction Partners

Human Origin Recognition Complex, Subunit 4 (ORC4) interaction partners

Since the site of one of the missense mutations in the human ORC4 alleles is conserved between humans and yeast, we sought to determine in what way this single amino acid change affects the process of chromosome replication, by introducing the comparable mutation into yeast (orc4Y232C).
HsOrc4 could have a fundamental function in the process of initiation of replication by remodeling the structure of origin of replication using the energy of supercoiled DNA.
compared with homozygous missense mutations, compound heterozygous mutations appeared to have a more severe effect on phenotype, causing more severe growth retardation in ORC4
identified three different mutations in the gene encoding ORC4, a component of the eukaryotic origin recognition complex, in five individuals with Meier-Gorlin syndrome
DNA binding activity of HsOrc4 depends on length and structure of DNA with triplex being the protein's preferred binding target.
Study using HCT116 haplo-insufficient cells and Orc2 hypomorphic cells demonstrates that the binding of human Ku to replication origins precedes that of Orc-3, -4, and -6 subunit binding.
describe 3 patients with B-cell lymphoproliferative disorders (2 with non-Hodgkin lymphoma and 1 with nonsecretory multiple myeloma) carrying a novel A286V mutation within ORC4L gene
Biochemical characterization of the mouse homolog

Mouse (Murine) Origin Recognition Complex, Subunit 4 (ORC4) interaction partners

Together, these data demonstrate that ORC4 oligomerization is required to form the ORC4 cage and that it is required for polar body extrusion.
ORC4 surrounds the chromatin that will be extruded in the polar body in both female meiotic divisions, then makes a transition from the cytoplasm to the chromosomes at zygotic anaphase, suggesting multiple roles for this replication licensing protein.

Fruit Fly (Drosophila melanogaster) Origin Recognition Complex, Subunit 4 (ORC4) interaction partners

The interaction of the Drosophila ENY2 protein with the ORC complex subunits was investigated. It is found that ORC4 and ORC6 subunits directly interact with ENY2.
Spotted-dick is a zinc-finger protein of Drosophila required for expression of Orc4 and S phase

ORC4 Antigen Profile

Antigen Summary

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene.

Alternative names and synonyms associated with ORC4

origin recognition complex subunit 4 (ORC4) antibody
origin recognition complex, subunit 4 (Orc4) antibody
Origin recognition complex subunit 4 (Orc4) antibody
origin recognition complex subunit 4 L homeolog (orc4.L) antibody
origin recognition complex, subunit 4 (orc4) antibody
origin recognition complex subunit 4 (orc4) antibody
origin recognition complex subunit 4 (CNM01830) antibody
origin recognition complex subunit 4 (Orc4) antibody
origin recognition complex subunit Orc4 (orc4) antibody

ATORC4 antibody
CG2917 antibody
Dmel\\CG2917 antibody
dmOrc4 antibody
F23H14.9 antibody
F23H14_9 antibody
fc50c03 antibody
mMmORC4 antibody
ORC antibody
orc4 antibody
orc4l antibody
Orc4P antibody
origin recognition complex subunit 4 antibody
rDmORC antibody
wu:fc50c03 antibody
zgc:85772 antibody

Protein level used designations for ORC4

origin recognition complex subunit 4 , origin recognition complex, subunit 4 homolog , CG2917-PA , CG2917-PB , Orc4-PA , Orc4-PB , origin recognition complex, subunit 4-like

GENE ID	SPECIES
5000	Homo sapiens
26428	Mus musculus
37970	Drosophila melanogaster
397923	Xenopus laevis
406462	Danio rerio
541939	Zea mays
814641	Arabidopsis thaliana
3255276	Cryptococcus neoformans var. neoformans JEC21
424307	Gallus gallus
476141	Canis lupus familiaris
529245	Bos taurus
295596	Rattus norvegicus
100689043	Cricetulus griseus
100055921	Equus caballus
2541298	Schizosaccharomyces pombe 972h-
100731516	Cavia porcellus

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