For best experience we recommend to activate Javascript in your browser.

Browse our anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5) Antibodies

Full name:: anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 5 Antibodies (PSMB5)

On www.antibodies-online.com are 69 Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5) Antibodies from 20 different suppliers available. Additionally we are shipping Proteasome (Prosome, Macropain) Subunit, beta Type, 5 Proteins (14) and and many more products for this protein. A total of 91 Proteasome (Prosome, Macropain) Subunit, beta Type, 5 products are currently listed.

Synonyms:: etID309919.2, fb59c07, LMPX, MB1, si:zc14a17.13, wu:fb59c07, x, zgc:86820

list all antibodies	Gene Name	GeneID	UniProt
	PSMB5	19173	O55234
	PSMB5	29425	P28075
	PSMB5	5693	P28074
Show all species Show all synonyms

Most Popular Reactivities for anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5) Antibodies

Select your species and application

anti-Mouse (Murine) Antibodies:

anti-Rat (Rattus) Antibodies:

anti-Human Antibodies:

All available anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 5 Antibodies

Go to our pre-filtered search.

Relevant Pathways for anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 5 Antibodies

Synthesis of DNA

More product categories related to Proteasome (Prosome, Macropain) Subunit, beta Type, 5 Antibody

Top referenced anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 5 Antibodies

Human Polyclonal PSMB5 Primary Antibody for WB - ABIN519378 : Grimm, Ott, Hörlacher, Weber, Höhn, Grune: Advanced-glycation-end-product-induced formation of immunoproteasomes: involvement of RAGE and Jak2/STAT1. in The Biochemical journal 2012 (PubMed)
Cow (Bovine) Polyclonal PSMB5 Primary Antibody for WB - ABIN2786720 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007 (PubMed)

More Antibodies against Proteasome (Prosome, Macropain) Subunit, beta Type, 5 Interaction Partners

Mouse (Murine) Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5) interaction partners

The P2Y2R enhances Ubiquitin-Proteasome System activity by increasing the subunits expression beta 5 and beta 1.
The role of the ubiquitin-proteasome system in pressure overloaded hearts andheart failure.
Probeta5 predominantly promotes integration into LMP2/MECL-1-containing precursors in IFNgamma-stimulated, LMP7-deficient cells and infected LMP7-deficient mice.
Data demonstrate that TNF-alpha expression is primarily dependent on both the chymotrypsin-and the trypsin-like activities of X, Y, Z subunits (PSMB5, PSMB6, PSMB7) of the proteasome.

Human Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5) interaction partners

PSMB5 mutations are associated with multiple myeloma.
PSMB5 knockdown could increase the expression of pro-apoptosis gene Bax and cleaved caspase-3
Our results suggest a potential role for PSMB5 as a biomarker and therapeutic target for Triple-negative breast cancer
Results identified PSMB5 Q62P mutation to underlie bortezomib resistance in Down-syndrome-associated acute myeloid leukemia cells.
We also discovered and replicated three genome-wide significant variants in previously unreported loci for RDW (SLC12A2 rs17764730, PSMB5 rs941718), and hematocrit (PROX1 rs3754140) and an upstream anti-sense long-noncoding RNA, LINC01184, as the likely causal variant
Data indicate that proteasomal subunit X PSMB5 is a target of signal transducer and activator of transcription 3 (STAT3).
Nuclear MB1 expression was an independent predictor of worse survival in ovarian cancer.
critical role of PSMB5 in 20S proteasome-mediated protection against replicative senescence, pointing to a possible strategy for maintaining the integrity of culture-expanded bone marrow stromal cells by manipulating the expression of PSMB5
The expression of proteasome beta5 decreases markedly in human atherosclerotic plaques.
Data indicate that treatment-emergent resistance to single-agent bortezomib was independent of variants in the proteasome genes PSMB1, PSMB5, PSMB6, PSMB8, PSMB9, and PSMB10.
Letter/Case Reports: proteasome subunit beta5t is expressed in cervical ectopic thymoma.
PSMB5 overexpression is associated with Bortezomib resistance in myeloma.
No mutations or differences in PSMB5 mRNA expression were seen before bortezomib treatment in 3 multiple myeloma patients, but after treatment, 1 patient showed PSMB5 upregulation associated with bortezomib resistance.
CDK5 regulation of proteasome subunit PSMB5 was identified as a probable route to antineoplastic drug sensitization.
Expression of mutated PSMB5 was associated with the prevention of the accumulation of unfolded proteins
interaction of TAP1 and TAP2 and P-glycoprotein with proteasome subunits beta-5 and beta-5i suggest direct targeting of antigenic peptides to the ER via a TAP-proteasome association and a possible role for P-glycoprotein
Proteasome activity can be genetically "upregulated" in lens cells by overexpression of beta5 catalytic subunit. Resulting increase in proteasome activity leads to decrease in oxidized proteins and enhanced cell survival following oxidative stress.
G322A mutation of the PSMB5 gene is a novel mechanism for bortezomib resistance.
nonsynonymous coding single nucleotide polymorphismsin the proteasome beta 5 subunit gene did not show significant effects on proteasome activity, but SNPs did influence transcription
Overexpression of PSMB5 is an important mechanism for bortezomib resistance in Jurkat cell lines.

Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5) Antigen Profile

Antigen Summary

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5)

proteasome subunit beta 5 (PSMB5) antibody
proteasome subunit beta 5 (psmb5) antibody
proteasome (prosome, macropain) subunit, beta type 5 (Psmb5) antibody
proteasome subunit beta 5 (Psmb5) antibody
proteasome subunit beta 5 L homeolog (psmb5.L) antibody
proteasome (prosome, macropain) subunit, beta type, 5 (PSMB5) antibody

etID309919.2 antibody
fb59c07 antibody
LMPX antibody
MB1 antibody
si:zc14a17.13 antibody
wu:fb59c07 antibody
x antibody
zgc:86820 antibody

Protein level used designations for PSMB5

, , , , , , , , , , , , , , , , , , proteasome subunit beta type 5 proteasome subunit beta type-5 proteasome (prosome, macropain) subunit, beta type, 5 macropain epsilon chain multicatalytic endopeptidase complex epsilon chain proteasome beta type subunit 5 proteasome chain 6 proteasome epsilon chain proteasome subunit X proteasome beta 5 subunit PSX large multifunctional protease X proteasome catalytic subunit 3 proteasome subunit MB1 proteasome subunit, beta type, 5 macropain chain 1 multicatalytic endopeptidase complex chain 1 proteasome C1 subunit proteasome chain 1 proteasome subunit C1

GENE ID	SPECIES
677719	Macaca mulatta
100379732	Xenopus (Silurana) tropicalis
19173	Mus musculus
29425	Rattus norvegicus
5693	Homo sapiens
534640	Bos taurus
30387	Danio rerio
100127332	Xenopus laevis
396003	Gallus gallus
480246	Canis lupus familiaris
100173015	Pongo abelii

Selected quality suppliers for anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5) Antibodies

Did you look for something else?

Phone:	+1 877 302 8632
Fax:	+1 888 205 9894 (Toll-free)
E-Mail:	orders@antibodies-online.com

Show all anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5) Antibodies with Pubmed References

Mouse (Murine) Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5) interaction partners

Human Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5) interaction partners

Antigen Summary

Alternative names and synonyms associated with Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5)

Protein level used designations for PSMB5