Browse our PSMD12 Proteins (PSMD12)

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3.

• proteasome 26S subunit, non-ATPase 12 (psmd12)
• proteasome 26S subunit, non-ATPase 12 (PSMD12)
• proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 (Psmd12)
• proteasome 26S subunit, non-ATPase 12 (Psmd12)

• 1500002F15Rik protein
• AI480719 protein
• P55 protein
• PSMD12 protein
• Rpn5 protein
• Show all synonym aliases
• wu:fb38a06 protein
• wu:fc34f08 protein
• wu:fc49f02 protein

26S proteasome non-ATPase regulatory subunit 12 , fc34f08 , proteasome 26S non-ATPase subunit 12 , proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 , 26S proteasome regulatory subunit RPN5 , 26S proteasome regulatory subunit p55 , 26S proteasome non-ATPase regulatory subunit 12-like