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Yeast (Saccharomyces cerevisiae) Polyclonal PSMD13 Primary Antibody for IP, WB - ABIN2452116
Takeuchi, Fujimuro, Yokosawa, Tanaka, Toh-e: Rpn9 is required for efficient assembly of the yeast 26S proteasome. in Molecular and cellular biology 2000
Data show that UBLCP1 (show UBLCP1 Antibodies) selectively binds to the 26S proteasome non-ATPase regulatory subunit 13 (19S regulatory particle) in regulating proteasome assembly.
Studies have found significant associations of the treatment response with the 26S proteasome non-ATPase subunit (show PSMD14 Antibodies) 9 (show ATP5G1 Antibodies) (PSMD9 (show PSMD9 Antibodies)), proteasome alpha type 7 (show PSMA7 Antibodies) subunit (PSMA7 (show PSMA7 Antibodies)) and PSMD13 genes.
The SIRT3 (show SIRT3 Antibodies) 5' flanking region encompasses the PSMD13 gene encoding the p40.5 regulator subunit of the 26S proteasome (show Psmd4 Antibodies).
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described.
26S proteasome non-ATPase regulatory subunit 13
, 26S proteasome regulatory subunit RPN9
, 26S proteasome regulatory subunit S11
, 26S proteasome regulatory subunit p40.5
, 26S proteasome subunit p40.5
, proteasome 26S non-ATPase subunit 13
, proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
, 26S proteasome p40.5 subunit
, 26S proteasome non-ATPase regulatory subunit 13-like