anti-PSME1 Antibodies

Protein Summary

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the alpha subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three alpha and three beta subunits combine to form a heterohexameric ring. Two transcripts encoding different isoforms have been identified.

Alternative names and synonyms associated with PSME1

• proteasome activator subunit 1 (psme1) antibody
• proteasome activator subunit 1 (PSME1) antibody
• proteasome activator subunit 1 (Psme1) antibody
• proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) (Psme1) antibody

• AW413925 antibody
• fk89d05 antibody
• IFI5111 antibody
• PA28a antibody
• PA28alpha antibody
• Show all synonym aliases
• REGalpha antibody
• wu:fk89d05 antibody

Protein level used designations for PSME1

proteasome activator complex subunit 1 , pA23-a , proteasome activator subunit 1 , 11S regulator complex subunit alpha , PA28a , PA28alpha , REG-alpha , activator of multicatalytic protease subunit 1 , protease (prosome, macropain) 28 subunit, alpha , proteasome (prosome, macropain) 28 subunit, alpha , proteasome activator 28 subunit alpha , 29-kD MCP activator subunit , IGUP I-5111 , interferon gamma up-regulated I-5111 protein , interferon-gamma IEF SSP 5111 , interferon-gamma-inducible protein 5111 , PA28 alpha subunit , proteasome activator 28 alpha subunit , proteasome activator PA28 alpha subunit