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Mismatch Repair Protein 2 Products

(Mismatch Repair Protein 2 (MSH2))

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This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].

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Featured Mismatch Repair Protein 2 Categories

Mismatch Repair Protein 2 Antibodies

High quality antibodies with extensive validation data.

Mismatch Repair Protein 2 ELISA Kits

Reliable ELISA kits for a wide range of species.

Mismatch Repair Protein 2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Mismatch Repair Protein 2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (9)
Cat. No. ABIN7193508
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, FACS, StM
Validations
  • (8)
Cat. No. ABIN6940081
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, PLA
Validations
  • (5)
Cat. No. ABIN518021
Quantity 100 μg
Datasheet Datasheet

Recommended Mismatch Repair Protein 2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968674
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951078
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6230961
Quantity 96 tests
Datasheet Datasheet

Recommended Mismatch Repair Protein 2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123971
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311438
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311436
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Mismatch Repair Protein 2 products

Faruk, Ibrahim, Aminu, Adamu, Abdullahi, Suleiman, Rafindadi, Mohammed, Iliyasu, Idoko, Saidu, Randawa, Musa, Ntekim, Shah, Abubakar, Adoke, Manko, Awasum: "Prognostic significance of BIRC7/Livin, Bcl-2, p53, Annexin V, PD-L1, DARC, MSH2 and PMS2 in colorectal cancer treated with FOLFOX chemotherapy with or without aspirin." in: PLoS ONE, Vol. 16, Issue 1, pp. e0245581, (2021) (PubMed).

Li, Wehrenberg, Waldman, Waldman: "Mismatch tolerance during homologous recombination in mammalian cells." in: DNA repair, Vol. 70, pp. 25-36, (2018) (PubMed).

Zhang, Yue, Wang, Li, Xin, Pang, Zheng, Xie: "Cisplatin upregulates MSH2 expression by reducing miR-21 to inhibit A549 cell growth." in: Biomedicine & pharmacotherapy, Vol. 67, Issue 2, pp. 97-102, (2014) (PubMed).

Wedrén, Lovmar, Humphreys, Magnusson, Melhus, Syvänen, Kindmark, Landegren, Fermér, Stiger, Persson, Baron, Weiderpass: "Estrogen receptor alpha gene polymorphism and endometrial cancer risk--a case-control study." in: BMC cancer, Vol. 8, pp. 322, (2009) (PubMed).

Leonardis: "Gene symbol: msh2. Disease: hereditary nonpolyposis colorectal cancer." in: Human genetics, Vol. 119, Issue 6, pp. 675, (2006) (PubMed).

Wang, Qin: "MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 26, pp. 15387-92, (2003) (PubMed).

Wilson, Ewel, Duguid, Eble, Lescoe, Fishel, Kelley: "Differential cellular expression of the human MSH2 repair enzyme in small and large intestine." in: Cancer research, Vol. 55, Issue 22, pp. 5146-50, (1995) (PubMed).

Cleaver: "It was a very good year for DNA repair." in: Cell, Vol. 76, Issue 1, pp. 1-4, (1994) (PubMed).

Fishel, Lescoe, Rao, Copeland, Jenkins, Garber, Kane, Kolodner: "The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer." in: Cell, Vol. 75, Issue 5, pp. 1027-38, (1994) (PubMed).

Leach, Nicolaides, Papadopoulos, Liu, Jen, Parsons, Peltomäki, Sistonen, Aaltonen, Nyström-Lahti: "Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer." in: Cell, Vol. 75, Issue 6, pp. 1215-25, (1994) (PubMed).

Synonyms and alternative names related to Mismatch Repair Protein 2

mutS homolog 2 (MSH2), mutS homolog 2 (Msh2), mutS homolog 2 (E. coli) (msh2), MUTS homolog 2 (MSH2), mutS homolog 2 L homeolog (msh2.L), MutS protein homolog 2 (msh2), AI788990, ATMSH2, COCA1, FCC1, HNPCC, HNPCC1, LCFS2, msh2, MUTS homolog 2, wu:fc06b02, wu:fc13e09, zgc:55333

Protein level used designations for Mismatch Repair Protein 2

  • DNA mismatch repair protein Msh2
  • hMSH2
  • mutS protein homolog 2
  • mismatch repair protein
  • MutS-like protein 2
  • mismatch repair protein Msh2
  • mutS-like protein 2
  • mutS homolog 2, colon cancer, nonpolyposis type 1
  • DNA mismatch repair protein MutS-homolog 2
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