anti-Human ABCC8 antibody for ELISA

Recommended ABCC8 Antibody (supplied by: Log in to see )

Antigen
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) Antibodies
  • ABC36
  • HHF1
  • HI
  • HRINS
  • MRP8
  • PHHI
  • SUR
  • SUR1
  • SUR1delta2
  • TNDM2
  • D930031B21Rik
  • Sur
  • Sur1
  • ATP binding cassette subfamily C member 8
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 8
  • ABCC8
  • Abcc8
Epitope
AA 611-711
72
67
14
4
4
3
2
2
1
1
1
1
1
1
Reactivity
Human
107
99
86
71
4
3
2
2
2
1
1
1
1
Host
Mouse
95
29
17
Clonality
Monoclonal
Conjugate
This ABCC8 antibody is un-conjugated
9
9
7
6
5
4
4
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
128
94
65
45
35
21
9
3
2
2
1
1
1
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Catalog No. ABIN4948191
$ 461.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.164179 ABIN520627 ELISA WB Mouse IgG1 kappa AA 611-710, partial Log in to see 3E1 0
12.164179 ABIN563068 ELISA WB Mouse IgG2a kappa AA 611-710, partial Log in to see 3G5 0
1 ABIN334499 ELISA WB Goat C-Term Log in to see Polyclonal 1
1 ABIN2464822 ELISA WB Goat C-Term Log in to see Polyclonal 0
1 ABIN490470 ELISA WB Goat AA 1559-1571 Log in to see Polyclonal 0
1 ABIN314241 ELISA WB Goat C-Term Log in to see Polyclonal 1
1 ABIN961136 ELISA WB Mouse IgG1, kappa AA 611-711 Log in to see 3E1 0
1 ABIN6284308 ELISA WB Rabbit IgG AA 500-580 Log in to see Polyclonal 0
1 ABIN520626 ELISA WB Mouse IgG2a kappa AA 611-710, partial Log in to see 3G5 0
1 ABIN6259686 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN5571772 ELISA WB Goat Log in to see Polyclonal 0
1 ABIN563067 ELISA WB Mouse AA 611-710, partial Log in to see Polyclonal 0
1 ABIN2560236 ELISA WB Goat IgG C-Term Log in to see Polyclonal 0
1 ABIN2193736 ELISA WB Biotin Goat C-Term Log in to see Polyclonal 0
1 ABIN2193739 ELISA WB PE Goat C-Term Log in to see Polyclonal 0
1 ABIN2193735 ELISA WB APC Goat C-Term Log in to see Polyclonal 0
1 ABIN2193734 ELISA WB Alkaline Phosphatase (AP) Goat C-Term Log in to see Polyclonal 0
1 ABIN2193737 ELISA WB FITC Goat C-Term Log in to see Polyclonal 0
1 ABIN2193741 ELISA WB Goat C-Term Log in to see Polyclonal 0
1 ABIN2747588 ELISA WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) Antibodies
Epitope AA 611-711
(72), (67), (14), (4), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(107), (99), (86), (71), (4), (3), (2), (2), (2), (1), (1), (1), (1)
Host Mouse
(95), (29), (17)
Clonality (Clone)
Monoclonal   ( )
Conjugate This ABCC8 antibody is un-conjugated
(9), (9), (7), (6), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Western Blotting (WB)
(128), (94), (65), (45), (35), (21), (9), (3), (2), (2), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-ABCC8 Antibody

Target Details ABCC8 Application Details Handling References for anti-ABCC8 antibody (ABIN4948191) Images
Specificity ABCC8 (NP_000343, 611 a.a. ~ 711 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Purified
Immunogen ABCC8 (NP_000343, 611 a.a. ~ 711 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3G5
Isotype IgG2a kappa
Plasmids, Primers & others

Target Details ABCC8

Product Details anti-ABCC8 Antibody Application Details Handling References for anti-ABCC8 antibody (ABIN4948191) Images back to top
Antigen
Alternative Name ABCC8 (ABCC8 Antibody Abstract)
Background The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed, however, the transcript variants have not been fully described.
Synonyms: ABC36, HI, HRINS, MRP8, PHHI, SUR, SUR1 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
Molecular Weight 177022 DA
Gene ID 6833
NCBI Accession NP_000343
Pathways Negative Regulation of Hormone Secretion

Application Details

Product Details anti-ABCC8 Antibody Target Details ABCC8 Handling References for anti-ABCC8 antibody (ABIN4948191) Images back to top
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed, however, the transcript variants have not been fully described.

Restrictions For Research Use only

Handling

Product Details anti-ABCC8 Antibody Target Details ABCC8 Application Details References for anti-ABCC8 antibody (ABIN4948191) Images back to top
Buffer Phosphate buffered saline, pH 7.2
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months

References for anti-ABCC8 antibody (ABIN4948191)

Product Details anti-ABCC8 Antibody Target Details ABCC8 Application Details Handling Images back to top
Background publications

Jablonski, McAteer, de Bakker, Franks, Pollin, Hanson, Saxena, Fowler, Shuldiner, Knowler, Altshuler, Florez: "Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program." in: Diabetes, Vol. 59, Issue 10, pp. 2672-81, 2010

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010

Ruaño, Thompson, Kane, Pullinger, Windemuth, Seip, Kocherla, Holford, Wu: "Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?" in: Pharmacogenomics, Vol. 11, Issue 7, pp. 959-71, 2010

Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, 2010

Ruchat, Vohl, Weisnagel, Rankinen, Bouchard, Pérusse: "Combining genetic markers and clinical risk factors improves the risk assessment of impaired glucose metabolism." in: Annals of medicine, Vol. 42, Issue 3, pp. 196-206, 2010

Images

Product Details anti-ABCC8 Antibody Target Details ABCC8 Application Details Handling References for anti-ABCC8 antibody (ABIN4948191) back to top
Supplier Images
Western Blotting (WB) image for anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 611-711) antibody (ABIN4948191) Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunoge...
ELISA image for anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (AA 611-711) antibody (ABIN4948191) Detection limit for recombinant GST tagged ABCC8 is approximately 0.03ng/ml as a capt...