anti-Human ABCC8 antibody for ELISA

Recommended ABCC8 Antibody (supplied by: Log in to see )

Antigen
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) Antibodies
  • ABC36
  • HHF1
  • HI
  • HRINS
  • MRP8
  • PHHI
  • SUR
  • SUR1
  • SUR1delta2
  • TNDM2
  • D930031B21Rik
  • Sur
  • Sur1
  • ATP binding cassette subfamily C member 8
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 8
  • ABCC8
  • Abcc8
Epitope
C-Term
72
66
4
4
3
3
2
1
1
1
1
1
1
Reactivity
Human
107
99
86
71
4
3
2
2
2
1
1
1
1
Host
Goat
96
29
16
Clonality
Polyclonal
Conjugate
This ABCC8 antibody is un-conjugated
9
9
7
6
5
4
4
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
128
94
65
45
35
21
9
3
2
2
1
1
1
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Catalog No. ABIN334499
$ 429.84
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.252602 ABIN6388663 ELISA WB Rabbit IgG AA 500-580 Log in to see Polyclonal 0
11.168276 ABIN4948191 ELISA WB Mouse IgG2a kappa AA 611-711 Log in to see 3G5 5
11.168276 ABIN563068 ELISA WB Mouse IgG2a kappa AA 611-710 Log in to see 3G5 0
11.168276 ABIN520627 ELISA WB Mouse IgG1 kappa AA 611-710 Log in to see 3E1 0
10 ABIN6259686 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
7 ABIN2433953 IHC ELISA Rabbit IgG Log in to see Polyclonal 0
7 ABIN2427351 IHC ELISA Rabbit IgG Log in to see Polyclonal 0
4 ABIN2464822 ELISA WB Goat C-Term Log in to see Polyclonal 0
4 ABIN490470 ELISA WB Goat AA 1559-1571 Log in to see Polyclonal 0
4 ABIN961136 ELISA WB Mouse IgG1, kappa AA 611-711 Log in to see 3E1 0
4 ABIN520626 ELISA WB Mouse IgG2a kappa AA 611-710 Log in to see 3G5 0
4 ABIN5571772 ELISA WB Goat Log in to see Polyclonal 0
4 ABIN2560236 ELISA WB Goat IgG C-Term Log in to see Polyclonal 0
4 ABIN563067 ELISA WB Mouse AA 611-710 Log in to see Polyclonal 0
1 ABIN2193739 ELISA WB PE Goat C-Term Log in to see Polyclonal 0
1 ABIN2193735 ELISA WB APC Goat C-Term Log in to see Polyclonal 0
1 ABIN2193734 ELISA WB Alkaline Phosphatase (AP) Goat C-Term Log in to see Polyclonal 0
1 ABIN2193736 ELISA WB Biotin Goat C-Term Log in to see Polyclonal 0
1 ABIN2193737 ELISA WB FITC Goat C-Term Log in to see Polyclonal 0
1 ABIN2193741 ELISA WB Goat C-Term Log in to see Polyclonal 0

General

Antigen ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) Antibodies
Epitope C-Term
(72), (66), (4), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(107), (99), (86), (71), (4), (3), (2), (2), (2), (1), (1), (1), (1)
Host Goat
(96), (29), (16)
Clonality
Polyclonal
Conjugate This ABCC8 antibody is un-conjugated
(9), (9), (7), (6), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Western Blotting (WB)
(128), (94), (65), (45), (35), (21), (9), (3), (2), (2), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-ABCC8 Antibody

Target Details ABCC8 Application Details Handling References for anti-ABCC8 antibody (ABIN334499) Images
Purpose SUR1 / ABCC8
Blocking Peptide Blocking peptide for this product available: ABIN368979
Sequence EFDKPEKLLS RKD
Predicted Reactivity Human, Mouse, Rat, Dog
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Grade Verified
Immunogen Peptide with sequence C-EFDKPEKLLSRKD, from the C Terminus of the protein sequence according to NP_000343.2.
Plasmids, Primers & others

Target Details ABCC8

Product Details anti-ABCC8 Antibody Application Details Handling References for anti-ABCC8 antibody (ABIN334499) Images back to top
Antigen
Alternative Name ABCC8 (ABCC8 Antibody Abstract)
Background ABCC8, SUR1, ATP-binding cassette, sub-family C (CFTR/MRP), member 8, ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, TNDM2, ATP-binding cassette, sub-family C, member 8, sulfonylurea receptor (hyperinsulinemia)
Gene ID 6833
NCBI Accession NP_000343
Pathways Negative Regulation of Hormone Secretion

Application Details

Product Details anti-ABCC8 Antibody Target Details ABCC8 Handling References for anti-ABCC8 antibody (ABIN334499) Images back to top
Application Notes

DS WB Results: Approx 170 kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 177 kDa according to NP_000343.2). Recommended concentration: 0.5-1.5 μg/mL. An additional band of unknown identity was also consistently observed at 23 kDa. This band was successfully blocked by incubation with the immunising peptide. We would appreciate any feedback from people in the field - have any such results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?

Peptide ELISA Statement: Peptide ELISA: antibody detection limit dilution 1:8000.

Restrictions For Research Use only

Handling

Product Details anti-ABCC8 Antibody Target Details ABCC8 Application Details References for anti-ABCC8 antibody (ABIN334499) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.

References for anti-ABCC8 antibody (ABIN334499)

Product Details anti-ABCC8 Antibody Target Details ABCC8 Application Details Handling Images back to top
Background publications

de Wet, Rees, Shimomura, Aittoniemi, Patch, Flanagan, Ellard, Hattersley, Sansom, Ashcroft: "Increased ATPase activity produced by mutations at arginine-1380 in nucleotide-binding domain 2 of ABCC8 causes neonatal diabetes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 48, pp. 18988-92, 2007

Images

Product Details anti-ABCC8 Antibody Target Details ABCC8 Application Details Handling References for anti-ABCC8 antibody (ABIN334499) back to top
Supplier Images
 image for anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (C-Term) antibody (ABIN334499) ABIN334499 (0.5µg/ml) staining of Human Cerebellum lysate (35µg protein in RIPA buffe...