anti-Rat (Rattus) ABCC8 antibody for Flow Cytometry

Recommended ABCC8 Antibody (supplied by: Log in to see )

Antigen
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) Antibodies
  • ABC36
  • HHF1
  • HI
  • HRINS
  • MRP8
  • PHHI
  • SUR
  • SUR1
  • SUR1delta2
  • TNDM2
  • D930031B21Rik
  • Sur
  • Sur1
  • ATP binding cassette subfamily C member 8
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 8
  • ABCC8
  • Abcc8
Reactivity
Human, Mouse (Murine), Rat (Rattus)
105
96
84
71
4
3
2
2
2
1
1
1
1
Host
Rabbit
96
26
17
Clonality
Polyclonal
Conjugate
This ABCC8 antibody is un-conjugated
9
9
7
6
5
4
4
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blotting (WB)
126
92
64
45
34
21
9
2
2
2
1
1
1
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Catalog No. ABIN5693055
$ 280.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5708360 FACS WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(105), (96), (84), (71), (4), (3), (2), (2), (2), (1), (1), (1), (1)
Host Rabbit
(96), (26), (17)
Clonality
Polyclonal
Conjugate This ABCC8 antibody is un-conjugated
(9), (9), (7), (6), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blotting (WB)
(126), (92), (64), (45), (34), (21), (9), (2), (2), (2), (1), (1), (1)
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Product Details anti-ABCC8 Antibody

Target Details ABCC8 Application Details Handling Images
Brand Picoband™
Sequence TIQREGTLKD FQRSECQLFE HWKTLMNRQD QELEKETVTE RKA
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Rabbit IgG polyclonal antibody for SUR1 detection. Tested with WB, IHC-F, ICC, FCM in Human,Mouse,Rat.
Immunogen A synthetic peptide corresponding to a sequence of human SUR1 (TIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVTERKA).
Plasmids, Primers & others

Target Details ABCC8

Product Details anti-ABCC8 Antibody Application Details Handling Images back to top
Antigen
Alternative Name ABCC8 (ABCC8 Antibody Abstract)
Background

Synonyms: ATP-binding cassette sub-family C member 8, Sulfonylurea receptor 1, ABCC8, HRINS, SUR, SUR1

Background: ATP-binding cassette transporter sub-family C member 8 is a protein that in humans is encoded by the ABCC8 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternatively spliced transcript variants have been found for this gene.

UniProt Q09428
Pathways Negative Regulation of Hormone Secretion

Application Details

Product Details anti-ABCC8 Antibody Target Details ABCC8 Handling Images back to top
Application Notes

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(F) and ICC.

Application Details: Western blot, 0.1-0.5&mu,g/mL
Immunohistochemistry(Frozen Section), 0.5-1&mu,g/mL
Immunocytochemistry, 0.5-1&mu,g/mL
Flow Cytometry, 1-3 μg/1x106 cells

Restrictions For Research Use only

Handling

Product Details anti-ABCC8 Antibody Target Details ABCC8 Application Details Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Buffer Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Images

Product Details anti-ABCC8 Antibody Target Details ABCC8 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) antibody (ABIN5693055) Western blot analysis of SUR1 using anti-SUR1 antibody . Electrophoresis was perform...
Flow Cytometry (FACS) image for anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) antibody (ABIN5693055) Flow Cytometry analysis of A431 cells using anti-ABCC8 antibody . Overlay histogram s...