anti-Pig (Porcine) CCR5 antibody for Western Blotting

Recommended CCR5 Antibody (supplied by: Log in to see )

Antigen
C-C Chemokine Receptor Type 5 (CCR5) Antibodies
  • CC-CKR-5
  • CCCKR5
  • CCR-5
  • CD195
  • CKR-5
  • CKR5
  • CMKBR5
  • IDDM22
  • Ckr5
  • Cmkbr5
  • CCR1-L
  • GPCR
  • CCR5
  • AM4-7
  • C-C motif chemokine receptor 5 (gene/pseudogene)
  • chemokine (C-C motif) receptor 5
  • C-C motif chemokine receptor 5
  • CCR5
  • Ccr5
Epitope
Middle Region
44
21
15
13
12
12
11
9
9
8
8
7
6
6
4
4
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Human, Pig (Porcine)
442
92
72
14
2
2
1
1
1
1
1
Host
Rabbit
198
190
64
15
12
Clonality
Polyclonal
Conjugate
This CCR5 antibody is un-conjugated
35
24
19
15
15
14
11
8
7
5
5
5
5
4
4
4
4
4
4
4
4
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
253
212
140
78
71
55
51
50
34
14
8
8
8
7
4
4
3
2
2
2
2
2
2
1
1
1
Options
Supplier
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Catalog No. ABIN2779385
$ 319.00
Plus shipping costs $45.00

General

Antigen C-C Chemokine Receptor Type 5 (CCR5) Antibodies
Epitope Middle Region
(44), (21), (15), (13), (12), (12), (11), (9), (9), (8), (8), (7), (6), (6), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Human, Pig (Porcine)
(442), (92), (72), (14), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(198), (190), (64), (15), (12)
Clonality
Polyclonal
Conjugate This CCR5 antibody is un-conjugated
(35), (24), (19), (15), (15), (14), (11), (8), (7), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(253), (212), (140), (78), (71), (55), (51), (50), (34), (14), (8), (8), (8), (7), (4), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-CCR5 Antibody

Target Details CCR5 Application Details Handling References for anti-CCR5 antibody (ABIN2779385) Images
Blocking Peptide Blocking peptide for this product available: ABIN974625
Sequence SHFPYSQYQF WKNFQTLKIV ILGLVLPLLV MVICYSGILK TLLRCRNEKK
Predicted Reactivity Cow: 92%, Human: 100%, Pig: 100%
Characteristics This is a rabbit polyclonal antibody against CCR5. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human CCR5
Plasmids, Primers & others

Target Details CCR5

Product Details anti-CCR5 Antibody Application Details Handling References for anti-CCR5 antibody (ABIN2779385) Images back to top
Antigen
Alternative Name CCR5 (CCR5 Antibody Abstract)
Background CCR5 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this protein was also detected in a promyeloblastic cell line, suggesting that CCR5 may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene.This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: CC-CKR-5, CCCKR5, CD195, CKR-5, CKR5, CMKBR5, IDDM22
Protein Interaction Partner: CST9L, IL24, ETV5, CTBP2, PSMA5, CCL3L3, ARL6IP5, PRAF2, DNM2, CCL8, STAT5A, CCL3L1, CCL16, CCL14, CCL13, CCR5, CCR2, PTK2B, CCL11, GNAQ, PTK2, STAT1, TXK, CCL5, CD4, CCL4, CCL3, CXCR4, CCL7, CCL2, LCK, JAK2, JAK1, GNAI3, GNAI2, GNAO1, GNAI1, ORM1, ADRBK2
Protein Size: 352
Molecular Weight 41 kDa
Gene ID 1234
NCBI Accession NM_000579, NP_000570
UniProt P51681
Pathways Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size

Application Details

Product Details anti-CCR5 Antibody Target Details CCR5 Handling References for anti-CCR5 antibody (ABIN2779385) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 352 AA

Restrictions For Research Use only

Handling

Product Details anti-CCR5 Antibody Target Details CCR5 Application Details References for anti-CCR5 antibody (ABIN2779385) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CCR5 antibody (ABIN2779385)

Product Details anti-CCR5 Antibody Target Details CCR5 Application Details Handling Images back to top
Background publications

Catano, Agan, Kulkarni, Telles, Marconi, Dolan, Ahuja: "Independent effects of genetic variations in mannose-binding lectin influence the course of HIV disease: the advantage of heterozygosity for coding mutations." in: The Journal of infectious diseases, Vol. 198, Issue 1, pp. 72-80, 2008

Images

Product Details anti-CCR5 Antibody Target Details CCR5 Application Details Handling References for anti-CCR5 antibody (ABIN2779385) back to top
Supplier Images
Western Blotting (WB) image for anti-C-C Chemokine Receptor Type 5 (CCR5) (Middle Region) antibody (ABIN2779385) Host: Rabbit Target Name: CCR5 Sample Tissue: Human HepG2 Whole Cell Antibody Dilutio...
Western Blotting (WB) image for anti-C-C Chemokine Receptor Type 5 (CCR5) (Middle Region) antibody (ABIN2779385) Host: Rabbit Target Name: CCR5 Sample Tissue: Human Jurkat Whole Cell Antibody Diluti...
Western Blotting (WB) image for anti-C-C Chemokine Receptor Type 5 (CCR5) (Middle Region) antibody (ABIN2779385) Host: Rabbit Target Name: CCR5 Sample Type: Human Fetal Liver Antibody Dilution: 1.0u...
Western Blotting (WB) image for anti-C-C Chemokine Receptor Type 5 (CCR5) (Middle Region) antibody (ABIN2779385) WB Suggested Anti-CCR5 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive...