Relevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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22 | ABIN617896 | IEM ICC IF IHC | Rabbit | IgG | Log in to see | Polyclonal | 36 |
General |
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Antigen | Chromogranin A (CHGA) Antibodies |
Reactivity | Buffalo (Bubalus), Cat (Feline), Chicken, Cow (Bovine), Dog (Canine), Duck, Fish, Guinea Pig, Hamster, Horse (Equine), Human, Monkey, Mouse (Murine), Ostrich (Struthio camelus), Pig (Porcine), Psittacula krameri, Rat (Rattus), Sheep (Ovine) Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | Un-conjugated Alternatives |
Application |
Immunoelectron Microscopy (IEM), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
Alternatives
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174 references available |
Supplier | Log in to see |
Product detailsTarget Details Application Details Handling References Images |
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Cross-Reactivity | Mammalian |
Characteristics | The antibody has a proven strong staining at a 1/1000 - 1/2000 dilution in rat adrenal medulla using Biotin-Streptavidin/HRP detection method. |
Purification | Whole Serum |
Immunogen | SP-1 Chromogranin A |
Isotype | IgG |
Target DetailsProduct details Application Details Handling References Images back to top |
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Antigen | |
Alternative Name | Chromogranin A (CHGA Antibody Abstract) |
Background |
Other Names: Pituitary secretory protein I, CgA, chromogranin A (parathyroid secretory protein 1) |
Gene ID | 281070 |
Pathways | Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling |
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Restrictions | For Research Use only |
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Format | Liquid |
Buffer | Contains ≤ 0.09 % sodium azide |
Preservative | Sodium azide |
Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Storage | 4 °C/-20 °C |
Storage Comment | After reconstitution, use immediately or refrigerate at 2 - 8 °C up to 2 days. For long-term storage aliquot antibody and freeze at -15 °C or lower. Avoid repeated freeze/thaw cycles. |
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Product cited in: |
Leblanc, Langlois, Coulombe, Vaillancourt-Lavigueur, Jones, Carrier, Boudreau, Rivard: "Epithelial Src homology region 2 domain-containing phosphatase-1 restrains intestinal growth, secretory cell differentiation, and tumorigenesis." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 31, pp. 3512-3526, 2017 Wang, Kwon, Singh, Islam, Liu, Sridhar, Hofmann, Browning: "Type 2 cGMP-dependent protein kinase regulates homeostasis by blocking c-Jun N-terminal kinase in the colon epithelium." in: Cell death and differentiation, Vol. 21, Issue 3, pp. 427-37, 2014 Reilly, Teo, Low, Amoyo-Brion, Dominguez-Brauer, Elia, Berger, Greicius, Pettersson, Mak: "Lipocalin 2 performs contrasting, location-dependent roles in APCmin tumor initiation and progression." in: Oncogene, Vol. 32, Issue 10, pp. 1233-9, 2013 Wolfs, Kallapur, Knox, Thuijls, Nitsos, Polglase, Collins, Kroon, Spierings, Shroyer, Newnham, Jobe, Kramer: "Antenatal ureaplasma infection impairs development of the fetal ovine gut in an IL-1-dependent manner." in: Mucosal immunology, Vol. 6, Issue 3, pp. 547-56, 2013 Rychel, Worley, Hardy, Webb: "Prolonged survival in an aged Labrador retriever with a metastatic insulinoma." in: Journal of the American Animal Hospital Association, Vol. 49, Issue 3, pp. 224-9, 2013 Ho, Sinha, Verzi, Bernt, Armstrong, Shivdasani: "DOT1L-mediated H3K79 methylation in chromatin is dispensable for Wnt pathway-specific and other intestinal epithelial functions." in: Molecular and cellular biology, Vol. 33, Issue 9, pp. 1735-45, 2013 Gozalo, Zerfas, Starost, Lambert, Elkins: "Pancreatic endocrine tumour with disseminated pulmonary thromboembolism in an owl monkey (Aotus nancymae)." in: Journal of comparative pathology, Vol. 149, Issue 1, pp. 132-6, 2013 Gracz, Fuller, Wang, Li, Stelzner, Dunn, Martin, Magness: "Brief report: CD24 and CD44 mark human intestinal epithelial cell populations with characteristics of active and facultative stem cells." in: Stem cells (Dayton, Ohio), Vol. 31, Issue 9, pp. 2024-30, 2013 Dipaola, Shivakumar, Pfister, Walters, Sabla, Bezerra: "Identification of intramural epithelial networks linked to peribiliary glands that express progenitor cell markers and proliferate after injury in mice." in: Hepatology (Baltimore, Md.), Vol. 58, Issue 4, pp. 1486-96, 2013 Feng, Sentani, Wiese, Sands, Green, Bommer, Cho, Fearon: "Sox9 induction, ectopic Paneth cells, and mitotic spindle axis defects in mouse colon adenomatous epithelium arising from conditional biallelic Apc inactivation." in: The American journal of pathology, Vol. 183, Issue 2, pp. 493-503, 2013 Schaffer, Weishaar, Han: "Endobronchial metastasis in a dog with sarcoma." in: Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, Vol. 25, Issue 4, pp. 546-50, 2013 Hu He, Juhl, Karadimos, El Khattabi, Fitzpatrick, Bonner-Weir, Sharma: "Differentiation of pancreatic endocrine progenitors reversibly blocked by premature induction of MafA." in: Developmental biology, Vol. 385, Issue 1, pp. 2-12, 2013 Grozinsky-Glasberg, Thomas, Strosberg, Pape, Felder, Tsolakis, Alexandraki, Fraenkel, Saiegh, Reissman, Kaltsas, Gross: "Metastatic type 1 gastric carcinoid: a real threat or just a myth?" in: World journal of gastroenterology : WJG, Vol. 19, Issue 46, pp. 8687-95, 2013 Gonzalez, Williamson, Piedrahita, Blikslager, Magness: "Cell lineage identification and stem cell culture in a porcine model for the study of intestinal epithelial regeneration." in: PLoS ONE, Vol. 8, Issue 6, pp. e66465, 2013 Roy, Langlois, Carrier, Boudreau, Rivard, Perreault: "Dual regulatory role for phosphatase and tensin homolog in specification of intestinal endocrine cell subtypes." in: World journal of gastroenterology : WJG, Vol. 18, Issue 14, pp. 1579-89, 2012 Wang, Kwon, Thangaraju, Singh, Liu, Jay, Hofmann, Ganapathy, Browning: "Type 2 cGMP-dependent protein kinase regulates proliferation and differentiation in the colonic mucosa." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 303, Issue 2, pp. G209-19, 2012 Erlandsen, Qvigstad, Fossmark, Bakke, Chen, Sandvik: "Regulated endocrine-specific protein 18 (RESP18) is localized to and regulated in A-like cells and G-cells in rat stomach." in: Regulatory peptides, Vol. 177, Issue 1-3, pp. 53-9, 2012 Stauffer, Orentas, Lincoln, Khan, Salcedo, Hixon, Back, Wei, Patidar, Song, Hurd, Tsokos, Lai, Eisenhofer, Weiss, Khan, Wigginton: "High-throughput molecular and histopathologic profiling of tumor tissue in a novel transplantable model of murine neuroblastoma: new tools for pediatric drug discovery." in: Cancer investigation, Vol. 30, Issue 5, pp. 343-63, 2012 Li, Kapoor, Giel-Moloney, Rindi, Leiter: "Notch signaling differentially regulates the cell fate of early endocrine precursor cells and their maturing descendants in the mouse pancreas and intestine." in: Developmental biology, Vol. 371, Issue 2, pp. 156-69, 2012 Lu, Germano, Ohning, Vu, Pisegna: "PAC1 deficiency in a murine model induces gastric mucosa hypertrophy and higher basal gastric acid output." in: Journal of molecular neuroscience : MN, Vol. 43, Issue 1, pp. 76-84, 2011 |
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Supplier Images |
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Antigen | CHGA |
Lot Number | 1436001 |
Method validated | Immunohistochemistry |
Positive Control | Macaque hippocampus sections |
Negative Control | No primary antibody |
Notes |
Passed. ABIN617895 specifically labels the targeted antigen in macaque hippocampus in IHC. No signal was detected in sample negative control tissue and in the secondary antibody only control. |
Primary Antibody | ABIN617895 |
Secondary Antibody | goat anti-rabbit IgG, biotin-conjugated antibody (Vector, BA-1000, lot W1002) |
Protocol |
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Experimental Notes |
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