anti-Mouse (Murine) PDE8B antibody for Western Blotting

Recommended PDE8B Antibody (supplied by: Log in to see )

Antigen
phosphodiesterase 8B (PDE8B) Antibodies
  • PDE8B
  • ADSD
  • PPNAD3
  • B230331L10Rik
  • C030047E14Rik
  • RNPDE8B
  • phosphodiesterase 8B
  • high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
  • PDE8B
  • LOC100468338
  • pde8b
  • Pde8b
Epitope
AA 296-324, Center
18
17
8
2
2
1
1
Reactivity
Mouse (Murine)
29
22
8
6
4
4
4
3
3
2
2
2
2
1
1
1
Host
Rabbit
45
Clonality
Polyclonal
Conjugate
This PDE8B antibody is un-conjugated
3
2
2
2
2
2
Application
Western Blotting (WB)
25
15
15
8
4
3
3
1
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Catalog No. ABIN1881646
$ 385.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
4.8063846 ABIN2789902 WB Rabbit Middle Region Log in to see Polyclonal 0
4.8063846 ABIN3001275 WB Rabbit IgG Log in to see Polyclonal 0
4 ABIN5538156 WB Rabbit Ig Fraction AA 296-324 Log in to see Polyclonal 0
1 ABIN1103531 WB Rabbit AA 388-437 Log in to see Polyclonal 0
1 ABIN2332311 ELISA WB Rabbit IgG AA 296-324, Center, Internal Region Log in to see Polyclonal 0
1 ABIN1922518 ELISA WB Alkaline Phosphatase (AP) Rabbit IgG AA 296-324 Log in to see Polyclonal 0
1 ABIN1922522 ELISA WB PE Rabbit IgG AA 296-324 Log in to see Polyclonal 0
1 ABIN1922519 ELISA WB APC Rabbit IgG AA 296-324 Log in to see Polyclonal 0
1 ABIN1922520 ELISA WB Biotin Rabbit IgG AA 296-324 Log in to see Polyclonal 0
1 ABIN1922521 ELISA WB FITC Rabbit IgG AA 296-324 Log in to see Polyclonal 0
1 ABIN1922523 ELISA WB HRP Rabbit IgG AA 296-324 Log in to see Polyclonal 0
1 ABIN2582980 ELISA WB Rabbit IgG AA 296-324 Log in to see Polyclonal 0
1 ABIN1807144 WB Rabbit AA 296-324 Log in to see Polyclonal 0
1 ABIN2332305 ELISA WB PE Rabbit IgG AA 296-324, Center, Internal Region Log in to see Polyclonal 0
1 ABIN2332309 ELISA WB FITC Rabbit IgG AA 296-324, Center, Internal Region Log in to see Polyclonal 0
1 ABIN2332310 ELISA WB HRP Rabbit IgG AA 296-324, Center, Internal Region Log in to see Polyclonal 0
1 ABIN2332307 ELISA WB APC Rabbit IgG AA 296-324, Center, Internal Region Log in to see Polyclonal 0
1 ABIN2795964 WB Rabbit Ig Fraction AA 296-324, Center Log in to see Polyclonal 0
1 ABIN2332308 ELISA WB Biotin Rabbit IgG AA 296-324, Center, Internal Region Log in to see Polyclonal 0
1 ABIN2332306 ELISA WB Alkaline Phosphatase (AP) Rabbit IgG AA 296-324, Center, Internal Region Log in to see Polyclonal 0

General

Antigen phosphodiesterase 8B (PDE8B) Antibodies
Epitope AA 296-324, Center
(18), (17), (8), (2), (2), (1), (1)
Reactivity Mouse (Murine)
(29), (22), (8), (6), (4), (4), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1)
Host Rabbit
(45)
Clonality (Clone)
Polyclonal   ( )
Conjugate This PDE8B antibody is un-conjugated
(3), (2), (2), (2), (2), (2)
Application Western Blotting (WB)
(25), (15), (15), (8), (4), (3), (3), (1)
Pubmed 3 references available
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Product Details anti-PDE8B Antibody

Target Details PDE8B Application Details Handling References for anti-PDE8B antibody (ABIN1881646) Images
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Immunogen This PDE8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-324 amino acids from the Central region of human PDE8B.
Clone RB42219
Plasmids, Primers & others

Target Details PDE8B

Product Details anti-PDE8B Antibody Application Details Handling References for anti-PDE8B antibody (ABIN1881646) Images back to top
Antigen
Alternative Name PDE8B (PDE8B Antibody Abstract)
Background The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.

Synonyms: PDE8B, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B, Cell proliferation-inducing gene 22 protein
NCBI Accession NP_001025024, NP_003710, NP_001025023, NP_001025022, NP_001025025
UniProt O95263
Pathways Negative Regulation of Hormone Secretion, cAMP Metabolic Process

Application Details

Product Details anti-PDE8B Antibody Target Details PDE8B Handling References for anti-PDE8B antibody (ABIN1881646) Images back to top
Application Notes WB: 1:1000
Restrictions For Research Use only

Handling

Product Details anti-PDE8B Antibody Target Details PDE8B Application Details References for anti-PDE8B antibody (ABIN1881646) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

References for anti-PDE8B antibody (ABIN1881646)

Product Details anti-PDE8B Antibody Target Details PDE8B Application Details Handling Images back to top
Product cited in:

Horvath, Faucz, Finkielstain, Nikita, Rothenbuhler, Almeida, Mericq, Stratakis: "Haplotype analysis of the promoter region of phosphodiesterase type 8B (PDE8B) in correlation with inactivating PDE8B mutation and the serum thyroid-stimulating hormone levels." in: Thyroid : official journal of the American Thyroid Association, Vol. 20, Issue 4, pp. 363-7, 2010

Shields, Freathy, Knight, Hill, Weedon, Frayling, Hattersley, Vaidya: "Phosphodiesterase 8B gene polymorphism is associated with subclinical hypothyroidism in pregnancy." in: The Journal of clinical endocrinology and metabolism, Vol. 94, Issue 11, pp. 4608-12, 2009

Bimpaki, Nesterova, Stratakis: "Abnormalities of cAMP signaling are present in adrenocortical lesions associated with ACTH-independent Cushing syndrome despite the absence of mutations in known genes." in: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 161, Issue 1, pp. 153-61, 2009

Images

Product Details anti-PDE8B Antibody Target Details PDE8B Application Details Handling References for anti-PDE8B antibody (ABIN1881646) back to top
Supplier Images
Western Blotting (WB) image for anti-phosphodiesterase 8B (PDE8B) (AA 296-324), (Center) antibody (ABIN1881646) PDE8B Antibody (Center) (ABIN1881646) western blot analysis in mouse heart tissue lys...