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|Antigen||Urotensin 2 (UTS2) Antibodies|
|Conjugate||This Urotensin 2 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA)
|2 references available|
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Product Details anti-Urotensin 2 AntibodyTarget Details Urotensin 2 Application Details Handling References for anti-Urotensin 2 antibody (ABIN181138) Images
|Specificity||This antibody detects Urotensin II (U-II).|
|Characteristics||Synonyms: Urotensin-II, U-II, UII, UNQ525/PRO1068|
|Purification||Affinity chromatography on Protein A|
|Immunogen||Human Urotensin II. Spleen cells from immunised Balb/c mice were fused with cells of theSp2/0 myeloma cell line.|
Target Details Urotensin 2Product Details anti-Urotensin 2 Antibody Application Details Handling References for anti-Urotensin 2 antibody (ABIN181138) Images back to top
|Alternative Name||Urotensin-2 (UTS2) (UTS2 Antibody Abstract)|
|Background||Urotensin II is a cyclic heptapeptide that functions both as a potent vasoconstrictor and a neurotransmitter/ neuromodulator. U-II circulates in the plasma as a zymogen, and is activated by the urotensin converting enzyme. U-II is the endogenous ligand for the G-protein coupled receptor 14 (GPR14), recently renamed the UT receptor. Changes in the expression of U-II and its receptor have been associated with cardiovascular and renal diseases, including atherosclerosis, myocardial infarction, and diabetic nephropathy.Synonyms: U-II, UII, UNQ525/PRO1068, Urotensin-II|
|Pathways||Negative Regulation of Hormone Secretion|
Application DetailsProduct Details anti-Urotensin 2 Antibody Target Details Urotensin 2 Handling References for anti-Urotensin 2 antibody (ABIN181138) Images back to top
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-Urotensin 2 Antibody Target Details Urotensin 2 Application Details References for anti-Urotensin 2 antibody (ABIN181138) Images back to top
|Buffer||PBS, pH 7.4 containing 0.09 % Sodium Azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C/-20 °C|
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
|Expiry Date||12 months|
References for anti-Urotensin 2 antibody (ABIN181138)Product Details anti-Urotensin 2 Antibody Target Details Urotensin 2 Application Details Handling Images back to top
Watanabe, Kanome, Miyazaki, Katagiri: "Human urotensin II as a link between hypertension and coronary artery disease." in: Hypertension research : official journal of the Japanese Society of Hypertension, Vol. 29, Issue 6, pp. 375-87, 2006
Nothacker, Clark: "From heart to mind. The urotensin II system and its evolving neurophysiological role." in: The FEBS journal, Vol. 272, Issue 22, pp. 5694-702, 2005