anti-Mouse (Murine) Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like Antibody (supplied by: Log in to see )

Antigen
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L) Antibodies
  • NEDD4-2
  • NEDD4.2
  • RSP5
  • hNEDD4-2
  • nedd4
  • nedd4-2
  • NEDD4
  • Nedd4-2
  • 1300012C07Rik
  • Nedd4b
  • neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
  • NEDD4L
  • neural precursor cell expressed, developmentally down-regulated gene 4-like
  • NEDD4L
  • LOC776799
  • nedd4l
  • Nedd4l
Epitope
pSer342
14
10
9
9
7
3
3
2
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
51
49
30
6
5
5
5
4
3
1
1
1
1
1
Host
Rabbit
59
7
Clonality
Polyclonal
Conjugate
Alexa Fluor 594
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
45
23
12
7
7
5
4
2
1
1
Options
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Catalog No. ABIN2804531
$ 427.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN875656 IF (p) Alexa Fluor 488 Rabbit IgG pSer342 Log in to see Polyclonal
1 ABIN875659 IF (p) Alexa Fluor 350 Rabbit IgG pSer342 Log in to see Polyclonal
1 ABIN875657 IF (p) Alexa Fluor 555 Rabbit IgG pSer342 Log in to see Polyclonal
1 ABIN875660 IF (p) Alexa Fluor 647 Rabbit IgG pSer342 Log in to see Polyclonal
1 ABIN744255 IF (p) FITC Rabbit IgG pSer342 Log in to see Polyclonal
1 ABIN744252 IF (p) Cy5 Rabbit IgG pSer342 Log in to see Polyclonal
1 ABIN744251 IF (p) Cy3 Rabbit IgG pSer342 Log in to see Polyclonal
1 ABIN744253 IF (p) Cy5.5 Rabbit IgG pSer342 Log in to see Polyclonal
1 ABIN744254 IF (p) Cy7 Rabbit IgG pSer342 Log in to see Polyclonal
1 ABIN744248 IF (p) IHC (p) WB Rabbit IgG pSer342 Log in to see Polyclonal
1 ABIN5007383 IF (p) Alexa Fluor 750 Rabbit IgG pSer342 Log in to see Polyclonal
1 ABIN5007382 IF (p) Alexa Fluor 680 Rabbit IgG pSer342 Log in to see Polyclonal

General

Antigen Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L) Antibodies
Epitope pSer342
(14), (10), (9), (9), (7), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(51), (49), (30), (6), (5), (5), (5), (4), (3), (1), (1), (1), (1), (1)
Host Rabbit
(59), (7)
Clonality
Polyclonal
Conjugate Alexa Fluor 594
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p))
(45), (23), (12), (7), (7), (5), (4), (2), (1), (1)
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Product details

Target details Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human NEDD4L around the phosphorylation site of Ser342
Isotype IgG

Target details

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Antigen
Alternative Name NEDD4L (NEDD4L Antibody Abstract)
Background

E3 ubiquitin-protein ligase accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. This protein inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. Furthermore, it promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5, and promotes the ubiquitination and degradation of SGK.

Synonyms: E3 ubiquitin protein ligase NEDD4 like protein, E3 ubiquitin-protein ligase NEDD4-like, E3 ubiquitin-protein ligase NEDD4-like protein, KIAA0439, NED4L_HUMAN, NEDD4 2, NEDD4 2c, NEDD4-2, NEDD4-2a, NEDD4.2, NEDD4b, NEDD4L, NEDD4La, NEDD4Lb, NEDD4Lc, NEDD4Ld, NEDD4Le, NEDD4Lf, NEDD4Lg, NEDD4Lh, NEDL3, Neural precursor cell expressed developmentally down regulated 4 like E3 ubiquitin protein ligase, Neural precursor cell expressed, developmentally down regulated 4 like, RSP5, Ubiquitin protein ligase Rsp5.

Gene ID 23327
Research Area Enzymes
Pathways Negative Regulation of Transporter Activity

Application Details

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Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

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Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months