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NGEF Proteins

(Neuronal Guanine Nucleotide Exchange Factor (NGEF))
Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).
NGEF Protein (AA 612-710) (GST tag) NGEF Protein (AA 612-710) (GST tag) NGEF Protein (AA 612-710) (GST tag) (ABIN1312527)

NGEF Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

NGEF Protein (AA 1-710) (His tag) NGEF Protein (AA 1-710) (His tag) NGEF Protein (AA 1-710) (His tag) (ABIN3094103)

Crystallography grade NGEF Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS

NGEF Protein (AA 1-710) (His tag) NGEF Protein (AA 1-710) (His tag) NGEF Protein (AA 1-710) (His tag) (ABIN3136476)

Crystallography grade NGEF Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS

NGEF Proteins by Grade

Find NGEF Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

NGEF Proteins by Origin

Find NGEF Proteins for a variety of species such as anti-Human NGEF, anti-Mouse NGEF, anti-Rat NGEF. The species listed below are among those available. Click on a link to go to the corresponding products.

NGEF Proteins by Source

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NGEF Proteins by Protein Type

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NGEF Proteins by Application

Find NGEF Proteins validated for a specific application such as ELISA, WB, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular NGEF Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312527
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094103
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136476
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2727241
Quantity 20 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1629826
Quantity 1 mg
Datasheet Datasheet

Aliases for NGEF Proteins

neuronal guanine nucleotide exchange factor (NGEF) Proteins
neuronal guanine nucleotide exchange factor (Ngef) Proteins
ARHGEF27 Proteins
Besh3 Proteins
EPHEXIN Proteins
ephexin Proteins
Ephexin-1 Proteins
ephexin-1 Proteins
Tims2 Proteins
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