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anti-Human PRDM4 Antibodies:
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Human Polyclonal PRDM4 Primary Antibody for ELISA, WB - ABIN250305
Chittka, Arevalo, Rodriguez-Guzman, Pérez, Chao, Sendtner: The p75NTR-interacting protein SC1 inhibits cell cycle progression by transcriptional repression of cyclin E. in The Journal of cell biology 2004
Human Polyclonal PRDM4 Primary Antibody for ICC, IF - ABIN4347211
Bogani, Morgan, Nelson, Costello, McGouran, Kessler, Robertson, Bikoff: The PR/SET domain zinc finger protein Prdm4 regulates gene expression in embryonic stem cells but plays a nonessential role in the developing mouse embryo. in Molecular and cellular biology 2013
Both Prdm 4 and Prdm 5 are expressed in human corneal endothelium, primary hCECs and in HCECs-12 cells, characterised by expression of the Na(+)/K(+)-ATPase.
PRDM4 zinc knuckle by NMR spectroscopy.
Results suggest that Prdm4 functions redundantly with other transcriptional partners to cooperatively regulate gene expression in the embryo and adult animal.
SC1 and PRMT5 are components of an epigenetic regulatory complex that maintains the "stem-like" cellular state of the neural stem cells.
The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. An elevated expression level of this gene has been observed in PC12 cells treated with nerve growth factor, beta polypeptide (NGF). This gene is located in a chromosomal region that is thought to contain tumor suppressor genes.
PR domain zinc finger protein 4
, PR domain containing 4
, PR domain-containing protein 4
, PR-domain zinc-finger protein PFM1