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Both Prdm 4 and Prdm 5 (show PRDM5 Proteins) are expressed in human corneal endothelium, primary hCECs and in HCECs-12 cells, characterised by expression of the Na(+)/K(+)-ATPase (show ATP1A1 Proteins).
PRDM4 zinc knuckle by NMR spectroscopy.
Results suggest that Prdm4 functions redundantly with other transcriptional partners to cooperatively regulate gene expression in the embryo and adult animal.
SC1 (show ALCAM Proteins) and PRMT5 (show PRMT5 Proteins) are components of an epigenetic regulatory complex that maintains the "stem-like" cellular state of the neural stem cells.
The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. An elevated expression level of this gene has been observed in PC12 cells treated with nerve growth factor, beta polypeptide (NGF). This gene is located in a chromosomal region that is thought to contain tumor suppressor genes.
PR domain zinc finger protein 4
, PR domain containing 4
, PR domain-containing protein 4
, PR-domain zinc-finger protein PFM1