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Bax: antibody against pro-apoptotic marker

can form homodimers, and also heterodimerizes with and proteins. This is possible because is a member of the family of apoptosis-associated proteins. Apoptosis can be induced by a variety of internal and external stimuli including growth factor deprivation, cytokine treatment, antigen-receptor engagement, cell-cell interactions, irradiation and glucocorticoid treatment.

exerts a pro-apoptotic effect on cells by targeting mitochondrial membranes, inducing mitochondrial damage and subsequent cell death. ’s mode of action is to puncture the outer mitochondrial membrane.

This monoclonal (5B7) antibody is specific for mouse and suitable for Western Blotting.
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