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|Antigen||B-Cell CLL/lymphoma 3 (BCL3) Antibodies|
|Conjugate||This BCL3 antibody is un-conjugated Alternatives|
Dot Blot (DB), Immunocytochemistry (ICC), Western Blotting (WB)
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Product Details anti-BCL3 AntibodyTarget Details BCL3 Application Details Handling Images
|Cross-Reactivity||Human, Mouse (Murine), Rat (Rattus)|
|Cross-Reactivity (Details)||Other species not studied.|
|Purification||Protein G affinity chromatography|
|Immunogen||BCL3 antibody was raised in mouse using recombinant Human B-Cell Cll/Lymphoma 3 (Bcl3)|
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|Alternative Name||BCL3 (BCL3 Antibody Abstract)|
|Background||This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. Synonyms: Monoclonal BCL3 antibody, Anti-BCL3 antibody, B-cell lymphoma 3 encoded protein antibody, BCL4 antibody, D19S37 antibody.|
|Pathways||NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus|
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WB: 0.2-2 µg/mL
Optimal conditions should be determined by the investigator.
|Restrictions||For Research Use only|
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|Buffer||BCL3 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).|
|Precaution of Use||This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|Storage Comment||Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.|
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