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|Antigen||B-Cell CLL/lymphoma 3 (BCL3) Antibodies|
|Epitope||AA 199-216, Middle Region Alternatives|
|Reactivity||Human, Rat (Rattus) Alternatives|
|Conjugate||This BCL3 antibody is un-conjugated Alternatives|
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-BCL3 AntibodyTarget Details BCL3 Application Details Handling Images
|Purpose||Rabbit IgG polyclonal antibody for B-cell lymphoma 3 protein(BCL3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.|
Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
Rabbit IgG polyclonal antibody for B-cell lymphoma 3 protein(BCL3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: B-cell CLL/lymphoma 3
Protein Name: B-cell lymphoma 3 protein(BCL-3)
|Purification||Immunogen affinity purified.|
|Immunogen||A synthetic peptide corresponding to a sequence in the middle region of human Bcl3(199-216aa MALDRHGQTAAHLACEHR), different from the related rat and mouse sequences by one amino acid.|
Target Details BCL3Product Details anti-BCL3 Antibody Application Details Handling Images back to top
|Alternative Name||BCL3 (BCL3 Antibody Abstract)|
B-cell lymphoma 3-encoded protein is a protein that in humans is encoded by the BCL3 gene. This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. The BCL3 gene is mapped to human chromosome 19. This protein functions as a transcriptional coactivator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.
Synonyms: B cell CLL/lymphoma 3 antibody|B cell leukemia/lymphoma 3 antibody|B cell lymphoma 3 encoded protein antibody|B-cell lymphoma 3 protein antibody|Bcl 3 antibody|BCL 4 antibody|BCL-3 antibody|Bcl3 antibody|BCL3_HUMAN antibody|BCL4 antibody|Chronic lymphatic leukemia protein antibody|D19S37 antibody|Protein Bcl 3 antibody|Proto-oncogene BCL3 antibody
|Pathways||NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus|
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
|Restrictions||For Research Use only|
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|Reconstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.|
|Preservative||Thimerosal (Merthiolate), Sodium azide|
|Precaution of Use||This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
|Expiry Date||12 months|
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