anti-Human EGFR antibody for Blocking Reagent

Recommended EGFR Antibody (supplied by: Log in to see )

Antigen
Epidermal Growth Factor Receptor (EGFR) Antibodies
  • C-erb
  • CG10079
  • D-EGFR
  • D-Egf
  • DEGFR
  • DER
  • DER flb
  • DER/EGFR
  • DER/faint little ball
  • DER/top
  • DER/torpedo
  • DER1
  • DEgfr
  • Degfr
  • Der
  • DmHD-33
  • Dmel\\CG10079
  • EFG-R
  • EGF-R
  • EGFR
  • EGFr
  • EGfr
  • EK2-6
  • Egf
  • Egf-r
  • EgfR
  • El
  • Elp
  • Elp-1
  • Elp-B1
  • Elp-B1RB1
  • HD-33
  • TOP
  • Torpedo/DER
  • Torpedo/Egfr
  • c-erbB
  • d-egf-r
  • dEGFR
  • dEGFR1
  • dEgfr
  • der
  • egfr
  • flb
  • l(2)05351
  • l(2)09261
  • l(2)57DEFa
  • l(2)57EFa
  • l(2)57Ea
  • mor1
  • top
  • top/DER
  • top/flb
  • torpedo/Egfr
  • torpedo/egfr
  • EGFR12
  • EGFR15
  • egfr1
  • Erbb2
  • ERBB
  • ERBB1
  • HER1
  • PIG61
  • mENA
  • ErbB-1
  • Errp
  • 9030024J15Rik
  • AI552599
  • Erbb
  • Errb1
  • Wa5
  • wa-2
  • wa2
  • epidermal growth factor receptor
  • Epidermal growth factor receptor
  • epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
  • EGFR
  • Egfr
  • egfra
  • egfr1
  • LOC5564544
Epitope
Extracellular Domain
150
137
64
63
58
57
56
54
53
52
48
48
43
42
39
36
33
30
30
29
27
25
25
25
22
19
18
18
18
18
17
16
16
16
16
15
15
15
15
15
14
14
13
11
9
9
8
8
8
7
6
6
6
6
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
2442
850
682
29
24
18
17
15
15
4
4
3
2
2
1
1
1
Host
Rabbit
1477
861
81
44
9
5
2
1
1
Antibody Type
Recombinant Antibody
Clonality
Chimeric
Conjugate
This EGFR antibody is un-conjugated
104
82
73
65
56
54
54
32
32
28
28
28
28
28
28
28
26
25
24
24
21
21
21
21
21
21
20
18
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Blocking Reagent (BR), Flow Cytometry (FACS), Western Blotting (WB)
1468
685
612
556
504
272
263
230
124
84
66
56
40
24
19
14
12
11
10
5
4
4
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
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Catalog No. ABIN5668061
$ 345.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5668059 BR FACS Rabbit IgG, kappa Log in to see Chimeric
1 ABIN5668058 BR FACS Human IgG1, kappa Log in to see C225 (Cetuximab)
1 ABIN5668060 BR FACS WB Human IgG1, kappa Extracellular Domain Log in to see Matuzumab
1 ABIN385796 BR IHC (p) IP WB Biotin Mouse IgG1 Extracellular Domain Log in to see 111-6
1 ABIN385423 BR FACS IP Mouse IgG2a Extracellular Domain Log in to see 528
1 ABIN385433 Inhibition BR IP Mouse IgG1 Extracellular Domain Log in to see 225
1 ABIN410781 BR FACS IP Biotin Mouse IgG2a Extracellular Domain Log in to see 528
1 ABIN5526185 BR FACS WB Mammalian Cells IgG1 kappa Log in to see
1 ABIN385798 BR IHC (p) IP WB Mouse IgG1 Extracellular Domain Log in to see 111-6
1 ABIN385428 Inhibition BR FACS IP Mouse IgG2a Extracellular Domain Log in to see 528

General

Antigen Epidermal Growth Factor Receptor (EGFR) Antibodies
Epitope Extracellular Domain
(150), (137), (64), (63), (58), (57), (56), (54), (53), (52), (48), (48), (43), (42), (39), (36), (33), (30), (30), (29), (27), (25), (25), (25), (22), (19), (18), (18), (18), (18), (17), (16), (16), (16), (16), (15), (15), (15), (15), (15), (14), (14), (13), (11), (9), (9), (8), (8), (8), (7), (6), (6), (6), (6), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(2442), (850), (682), (29), (24), (18), (17), (15), (15), (4), (4), (3), (2), (2), (1), (1), (1)
Host Rabbit
(1477), (861), (81), (44), (9), (5), (2), (1), (1)
Clonality (Clone)
Chimeric   ( )
Conjugate This EGFR antibody is un-conjugated
(104), (82), (73), (65), (56), (54), (54), (32), (32), (28), (28), (28), (28), (28), (28), (28), (26), (25), (24), (24), (21), (21), (21), (21), (21), (21), (20), (18), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Blocking Reagent (BR), Flow Cytometry (FACS), Western Blotting (WB)
(1468), (685), (612), (556), (504), (272), (263), (230), (124), (84), (66), (56), (40), (24), (19), (14), (12), (11), (10), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
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Product Details anti-EGFR Antibody

Target Details EGFR Application Details Handling Images
Specificity Binds to human EGFR.
Characteristics Rabbit IgG based on the original Human IgG1
Purification Purified antibody.
Purity > 98 % as determined by SDS-PAGE
Endotoxin Level Endotoxin is < 1.0 EU/mg as determined by the LAL method
Immunogen Domain III of the extracellular domain of human EGRF.
Clone Matuzumab
Isotype IgG, kappa

Target Details EGFR

Product Details anti-EGFR Antibody Application Details Handling Images back to top
Antigen
Alternative Name EGFR (EGFR Antibody Abstract)
Background Epidermal Growth Factor Receptor, mAb425
Research Area Cancer, Growth Factors, Hormones, Receptors, Tyrosine Kinases
Pathways NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation

Application Details

Product Details anti-EGFR Antibody Target Details EGFR Handling Images back to top
Application Notes This antibody binds to human EGFR at a side distinct frm the antigen binding site, preventing conformational re-arrangement required for dimerization, a process essential for high-affinitiy ligand binding (Schmiedel 2008).
Comment

This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions For Research Use only

Handling

Product Details anti-EGFR Antibody Target Details EGFR Application Details Images back to top
Buffer PBS with 0.02 % Proclin 300.
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.