anti-Human EGFR antibody for Immunohistochemistry

Recommended EGFR Antibody (supplied by: Log in to see )

Antigen
Epidermal Growth Factor Receptor (EGFR) Antibodies
  • C-erb
  • CG10079
  • D-EGFR
  • D-Egf
  • DEGFR
  • DER
  • DER flb
  • DER/EGFR
  • DER/faint little ball
  • DER/top
  • DER/torpedo
  • DER1
  • DEgfr
  • Degfr
  • Der
  • DmHD-33
  • Dmel\\CG10079
  • EFG-R
  • EGF-R
  • EGFR
  • EGFr
  • EGfr
  • EK2-6
  • Egf
  • Egf-r
  • EgfR
  • El
  • Elp
  • Elp-1
  • Elp-B1
  • Elp-B1RB1
  • HD-33
  • TOP
  • Torpedo/DER
  • Torpedo/Egfr
  • c-erbB
  • d-egf-r
  • dEGFR
  • dEGFR1
  • dEgfr
  • der
  • egfr
  • flb
  • l(2)05351
  • l(2)09261
  • l(2)57DEFa
  • l(2)57EFa
  • l(2)57Ea
  • mor1
  • top
  • top/DER
  • top/flb
  • torpedo/Egfr
  • torpedo/egfr
  • EGFR12
  • EGFR15
  • egfr1
  • Erbb2
  • ERBB
  • ERBB1
  • HER1
  • PIG61
  • mENA
  • ErbB-1
  • Errp
  • 9030024J15Rik
  • AI552599
  • Erbb
  • Errb1
  • Wa5
  • wa-2
  • wa2
  • epidermal growth factor receptor
  • Epidermal growth factor receptor
  • epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
  • EGFR
  • Egfr
  • egfra
  • egfr1
  • LOC5564544
Epitope
AA 693-893
162
114
67
63
62
60
58
56
55
52
52
50
42
40
40
34
33
32
31
30
29
28
27
24
23
19
18
18
18
17
17
17
17
17
16
16
16
15
15
15
15
15
15
15
11
10
9
8
7
7
6
6
6
6
6
6
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
2708
962
789
31
27
20
19
16
14
7
4
3
2
2
2
2
2
2
2
1
1
1
1
1
Host
Mouse
1585
1014
82
44
14
5
2
1
1
Clonality
Monoclonal
Conjugate
This EGFR antibody is un-conjugated
110
83
82
72
62
56
54
36
32
32
29
28
28
28
28
28
28
26
25
24
24
21
21
21
21
21
20
18
17
17
8
8
8
8
8
8
8
8
8
8
8
8
8
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
1650
827
720
682
547
423
272
255
145
89
86
60
55
40
26
22
19
11
10
9
8
4
4
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
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Catalog No. ABIN1724890
$ 430.10
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
8.538242 ABIN4900628 CyTOF FACS ICC IHC SimWes WB Rabbit IgG pTyr1173 Log in to see Polyclonal 5
8.538242 ABIN4880696 ELISA FACS IHC WB Mouse IgG1 AA 693-893 Log in to see 7A6F12 0
8.538242 ABIN2706075 IC IF IHC WB Rabbit pSer693 Log in to see Polyclonal 0
8.538242 ABIN2801210 IC IF IP IHC WB Rabbit C-Term, pTyr1016 Log in to see Polyclonal 0
8.538242 ABIN2704750 IHC WB Rabbit C-Term Log in to see Polyclonal 0
8.538242 ABIN2706077 IHC WB Rabbit Center Log in to see Polyclonal 0
8.538242 ABIN2706078 IC IF IHC WB Rabbit Center Log in to see Polyclonal 0
8.538242 ABIN2704752 IC IF IHC WB Rabbit C-Term Log in to see Polyclonal 0
8.538242 ABIN2704751 IP IHC WB Rabbit C-Term Log in to see Polyclonal 0
8.538242 ABIN4307206 IHC IHC (p) Rabbit IgG Log in to see Polyclonal 1
8.538242 ABIN1532852 IHC ELISA WB Rabbit IgG AA 1139-1188 Log in to see Polyclonal 1
8.538242 ABIN4899925 CyTOF ELISA (Capture) FACS ICC IHC IP WB Goat IgG AA 25-645 Log in to see Polyclonal 6
8.538242 ABIN1872454 IHC WB Rabbit IgG Log in to see Polyclonal 0
8.538242 ABIN1532194 IHC ELISA WB Rabbit IgG AA 651-700 Log in to see Polyclonal 0
8.538242 ABIN1532195 IF IHC ELISA WB Rabbit IgG AA 661-710 Log in to see Polyclonal 0
8.538242 ABIN1531178 IF IHC ELISA WB Rabbit IgG AA 661-710, pThr693 Log in to see Polyclonal 0
8.538242 ABIN1531822 IHC ELISA WB Rabbit IgG AA 1161-1210, pTyr1197 Log in to see Polyclonal 0
8.538242 ABIN1531818 IHC ELISA WB Rabbit IgG AA 1041-1090, pSer1070 Log in to see Polyclonal 0
8.538242 ABIN1531819 IHC ELISA WB Rabbit IgG AA 1061-1110, pTyr1092 Log in to see Polyclonal 0
8.538242 ABIN1531312 IF IHC ELISA WB Rabbit IgG AA 986-1035, pTyr1016 Log in to see Polyclonal 0

General

Antigen Epidermal Growth Factor Receptor (EGFR) Antibodies
Epitope AA 693-893
(162), (114), (67), (63), (62), (60), (58), (56), (55), (52), (52), (50), (42), (40), (40), (34), (33), (32), (31), (30), (29), (28), (27), (24), (23), (19), (18), (18), (18), (17), (17), (17), (17), (17), (16), (16), (16), (15), (15), (15), (15), (15), (15), (15), (11), (10), (9), (8), (7), (7), (6), (6), (6), (6), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(2708), (962), (789), (31), (27), (20), (19), (16), (14), (7), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Host Mouse
(1585), (1014), (82), (44), (14), (5), (2), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This EGFR antibody is un-conjugated
(110), (83), (82), (72), (62), (56), (54), (36), (32), (32), (29), (28), (28), (28), (28), (28), (28), (26), (25), (24), (24), (21), (21), (21), (21), (21), (20), (18), (17), (17), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(1650), (827), (720), (682), (547), (423), (272), (255), (145), (89), (86), (60), (55), (40), (26), (22), (19), (11), (10), (9), (8), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-EGFR Antibody

Target Details EGFR Application Details Handling References for anti-EGFR antibody (ABIN1724890) Images
Purification Purified
Immunogen Purified recombinant fragment of human EGFR (AA 693-893) expressed in E. Coli.
Clone 7A6F12
Isotype IgG1
Plasmids, Primers & others

Target Details EGFR

Product Details anti-EGFR Antibody Application Details Handling References for anti-EGFR antibody (ABIN1724890) Images back to top
Antigen
Alternative Name EGFR (EGFR Antibody Abstract)
Background The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. ,
Molecular Weight 175 kDa
Gene ID 1956
HGNC 1956
Pathways NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation

Application Details

Product Details anti-EGFR Antibody Target Details EGFR Handling References for anti-EGFR antibody (ABIN1724890) Images back to top
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Restrictions For Research Use only

Handling

Product Details anti-EGFR Antibody Target Details EGFR Application Details References for anti-EGFR antibody (ABIN1724890) Images back to top
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage

References for anti-EGFR antibody (ABIN1724890)

Product Details anti-EGFR Antibody Target Details EGFR Application Details Handling Images back to top
Product cited in:

Derer, Bauer, Lohse, Scheel, Berger, Kellner, Peipp, Valerius: "Impact of epidermal growth factor receptor (EGFR) cell surface expression levels on effector mechanisms of EGFR antibodies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 11, pp. 5230-9, 2012

Minder, Bayha, Becker-Pauly, Sterchi: "Meprin? transactivates the epidermal growth factor receptor (EGFR) via ligand shedding, thereby enhancing colorectal cancer cell proliferation and migration." in: The Journal of biological chemistry, Vol. 287, Issue 42, pp. 35201-11, 2012

Images

Product Details anti-EGFR Antibody Target Details EGFR Application Details Handling References for anti-EGFR antibody (ABIN1724890) back to top
Supplier Images
ELISA image for anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody (ABIN1724890) anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody
Flow Cytometry (FACS) image for anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody (ABIN1724890) anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody (Image 2)
Western Blotting (WB) image for anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody (ABIN1724890) anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody (Image 3)
Western Blotting (WB) image for anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody (ABIN1724890) anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody (Image 4)
Western Blotting (WB) image for anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody (ABIN1724890) anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody (Image 5)
Immunohistochemistry (IHC) image for anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody (ABIN1724890) Immunohistochemical analysis of paraffin-embedded endometrial cancer tissues using EG...
Immunohistochemistry (IHC) image for anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody (ABIN1724890) Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using EGF...