anti-Human EGFR antibody for Inhibition Assay

Recommended EGFR Antibody (supplied by: Log in to see )

Antigen
Epidermal Growth Factor Receptor (EGFR) Antibodies
  • C-erb
  • CG10079
  • D-EGFR
  • D-Egf
  • DEGFR
  • DER
  • DER flb
  • DER/EGFR
  • DER/faint little ball
  • DER/top
  • DER/torpedo
  • DER1
  • DEgfr
  • Degfr
  • Der
  • DmHD-33
  • Dmel\\CG10079
  • EFG-R
  • EGF-R
  • EGFR
  • EGFr
  • EGfr
  • EK2-6
  • Egf
  • Egf-r
  • EgfR
  • El
  • Elp
  • Elp-1
  • Elp-B1
  • Elp-B1RB1
  • HD-33
  • TOP
  • Torpedo/DER
  • Torpedo/Egfr
  • c-erbB
  • d-egf-r
  • dEGFR
  • dEGFR1
  • dEgfr
  • der
  • egfr
  • flb
  • l(2)05351
  • l(2)09261
  • l(2)57DEFa
  • l(2)57EFa
  • l(2)57Ea
  • mor1
  • top
  • top/DER
  • top/flb
  • torpedo/Egfr
  • torpedo/egfr
  • EGFR12
  • EGFR15
  • egfr1
  • Erbb2
  • ERBB
  • ERBB1
  • HER1
  • PIG61
  • mENA
  • ErbB-1
  • Errp
  • 9030024J15Rik
  • AI552599
  • Erbb
  • Errb1
  • Wa5
  • wa-2
  • wa2
  • epidermal growth factor receptor
  • Epidermal growth factor receptor
  • epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
  • EGFR
  • Egfr
  • egfra
  • egfr1
  • LOC5564544
Reactivity
Human
2658
911
742
27
25
18
17
14
12
7
2
2
2
1
1
1
1
Host
Mouse
1545
1004
84
44
12
5
2
1
1
Clonality
Monoclonal
Conjugate
This EGFR antibody is un-conjugated
110
83
82
73
62
56
54
36
32
32
29
28
28
28
28
28
28
26
25
24
24
21
21
21
21
21
20
18
17
17
8
8
8
8
8
8
8
8
8
8
8
8
8
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
Application
Flow Cytometry (FACS), Inhibition Assay (InhA), Immunoprecipitation (IP)
1598
821
683
663
541
389
272
257
126
91
86
67
55
40
26
21
19
11
10
9
8
4
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
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Catalog No. ABIN3026442
$ 361.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN3026443 FACS InhA IP Mouse IgG2a, kappa Log in to see B1D8 0

General

Antigen Epidermal Growth Factor Receptor (EGFR) Antibodies
Reactivity Human
(2658), (911), (742), (27), (25), (18), (17), (14), (12), (7), (2), (2), (2), (1), (1), (1), (1)
Host Mouse
(1545), (1004), (84), (44), (12), (5), (2), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This EGFR antibody is un-conjugated
(110), (83), (82), (73), (62), (56), (54), (36), (32), (32), (29), (28), (28), (28), (28), (28), (28), (26), (25), (24), (24), (21), (21), (21), (21), (21), (20), (18), (17), (17), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (8), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Flow Cytometry (FACS), Inhibition Assay (InhA), Immunoprecipitation (IP)
(1598), (821), (683), (663), (541), (389), (272), (257), (126), (91), (86), (67), (55), (40), (26), (21), (19), (11), (10), (9), (8), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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Product Details anti-EGFR Antibody

Target Details EGFR Application Details Handling Images
No Cross-Reactivity Mouse (Murine), Rat (Rattus)
Characteristics This antibody reacts with the extracellular domain of EGF receptor and blocks the EGF/TGFa induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGF receptor. < a href=../search_result.php?search_txt=egfr>EGFR is type I receptor tyrosine kinase with sequence homology to < a href=../search_result.php?search_txt=erbb2>ErbB2, -3 -4 or < a href=../search_result.php?search_txt=her2>HER2, -3 -4. It binds to Epidermal Growth Factor (EGF), < a href=../search_result.php?search_txt=TGFa>Transforming Growth Factor-a (TGFa), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin.
Purification Protein G purified monoclonal antibody
Immunogen Microsomes from A431 cells were used as the immunogen for this antibody.
Clone B1D8
Isotype IgG2a, kappa
Plasmids, Primers & others

Target Details EGFR

Product Details anti-EGFR Antibody Application Details Handling Images back to top
Antigen
Alternative Name EGF Receptor (EGFR Antibody Abstract)
Background This antibody reacts with the extracellular domain of EGF receptor and blocks the EGF/TGFa induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGF receptor. < a href=../search_result.php?search_txt=egfr>EGFR is type I receptor tyrosine kinase with sequence homology to < a href=../search_result.php?search_txt=erbb2>ErbB2, -3 -4 or < a href=../search_result.php?search_txt=her2>HER2, -3 -4. It binds to Epidermal Growth Factor (EGF), < a href=../search_result.php?search_txt=TGFa>Transforming Growth Factor-a (TGFa), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin.
Gene ID 1956
Pathways NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation

Application Details

Product Details anti-EGFR Antibody Target Details EGFR Handling Images back to top
Application Notes The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.\. Functional Activity (Inhibition): antibody blocks EGF receptor activation, inhibits A431 cell proliferation, arrests tumor growth in vivo, affinity purification,IP: 1-2 μg/500 μg protein lysate,FACS: 0.5-1 μg/million cells
Restrictions For Research Use only

Handling

Product Details anti-EGFR Antibody Target Details EGFR Application Details Images back to top
Concentration 0.2 mg/mL
Buffer 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Store the EGF Receptor antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).