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|Antigen||Interleukin 1 alpha (IL1A) Antibodies|
|Conjugate||This IL1A antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-IL1A AntibodyTarget Details IL1A Application Details Handling Images
|Specificity||This antibody detects Interleukin 1 Alpha (IL1A).|
|Cross-Reactivity (Details)||Species reactivity (tested):Human.|
|Characteristics||Synonyms: IL-1 alpha, IL1F1, IL1A, Hematopoietin-1|
|Purification||Protein A Chromatography|
|Immunogen||Ni-NTA purified recombinant Human IL-1alpha, expressed in E. coli strain BL21 (DE3)|
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|Alternative Name||Interleukin-1 alpha / IL-1A (IL1A Antibody Abstract)|
|Background||Interleukin 1 alpha is synthesized as a 31 kDa promolecule that does not contain a signal sequence. Following proteolytic cleavage, the mature 17 kDa molecule is released as a result of cell injury or apoptosis. IL-1 alpha stimulates bone osteoclast activity, has a role in the modulation of extracellular fluid calcium homeostasis and apoptosis, activates T and B lymphocytes and NK cells, and functions in development. Movement of the IL-1 alpha promolecule to the nucleus in response to endotoxin where it augments transcription of proinflammatory genes has also been documented.Synonyms: Hematopoietin-1, IL-1 alpha, IL1A, IL1F1|
|Pathways||NF-kappaB Signaling, Autophagy|
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ELISA. Western blot (1/500-1/1000). Immunohistochemistry on Paraffin Sections (1/400).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
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|Buffer||PBS, pH 7.4 containing 0.03 % Sodium Azide as preservative|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C/-20 °C|
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
|Expiry Date||12 months|
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