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|Antigen||Interleukin 1, beta (IL1B) Antibodies|
|Epitope||AA 120-170 Alternatives|
|Reactivity||Dog (Canine), Human, Mouse (Murine), Rabbit, Rat (Rattus) Alternatives|
|Conjugate||This IL1B antibody is un-conjugated Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|11 references available|
|Supplier||Log in to see|
Product Details anti-IL1B AntibodyTarget Details IL1B Application Details Handling References for anti-IL1B antibody (ABIN728503) Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human IL-1beta|
Target Details IL1BProduct Details anti-IL1B Antibody Application Details Handling References for anti-IL1B antibody (ABIN728503) Images back to top
|Alternative Name||IL-1 beta (IL1B Antibody Abstract)|
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Subcellular location: Secreted
Synonyms: IL-1, IL1F2, IL1-BETA, Interleukin-1 beta, IL-1 beta, Catabolin, IL1B
|Research Area||Virology, Immunology, Cytokines, Cancer, Inflammation|
|Pathways||NF-kappaB Signaling, Interferon-gamma Pathway, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy|
Application DetailsProduct Details anti-IL1B Antibody Target Details IL1B Handling References for anti-IL1B antibody (ABIN728503) Images back to top
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL1B Antibody Target Details IL1B Application Details References for anti-IL1B antibody (ABIN728503) Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at -20°C|
|Expiry Date||12 months|
References for anti-IL1B antibody (ABIN728503)Product Details anti-IL1B Antibody Target Details IL1B Application Details Handling Images back to top
|Product cited in:||
Liu, Li, Weng: "Effect of BTXA on Inhibiting Hypertrophic Scar Formation in a Rabbit Ear Model." in: Aesthetic plastic surgery, Vol. 41, Issue 3, pp. 721-728, 2017 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Rabbit).
Hu, Liu, Deng, Ma, Sheng, Weng, Xu: "Immunoreactivities of IL-1β and IL-1R in oviduct of Chinese brown frog (Rana dybowskii) during pre-hibernation and the breeding period." in: Acta histochemica, Vol. 118, Issue 2, pp. 164-9, 2016
Du, Niu, Wang, Zhao, Kong, Zhang, Nan: "TLR4‑dependent signaling pathway modulation: A novel mechanism by which pioglitazone protects against nutritional fibrotic steatohepatitis in mice." in: Molecular medicine reports, Vol. 13, Issue 3, pp. 2159-66, 2016 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).
Xi, Hu, Guo, Wang, Sheng, Han, Yuan, Weng, Xu: "Immunoreactivities of NF-κB, IL-1β and IL-1R in the skin of Chinese brown frog (Rana dybowskii)." in: Acta histochemica, Vol. 119, Issue 1, pp. 64-70, 2016 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Heitzer, Kaiser, Kanagaratnam, Zendedel, Hartmann, Beyer, Johann: "Administration of 17β-Estradiol Improves Motoneuron Survival and Down-regulates Inflammasome Activation in Male SOD1(G93A) ALS Mice." in: Molecular neurobiology, 2016 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).
Wang, Chen, Li, Ma, Tang: "Anti-inflammatory cytokine TSG-6 inhibits hypertrophic scar formation in a rabbit ear model." in: European journal of pharmacology, Vol. 751, pp. 42-9, 2015
Johann, Heitzer, Kanagaratnam, Goswami, Rizo, Weis, Troost, Beyer: "NLRP3 inflammasome is expressed by astrocytes in the SOD1 mouse model of ALS and in human sporadic ALS patients." in: Glia, 2015
Li, Dan, Nie, Hu, Gesang, Bianba, Ze, Ciren: "CD14 knockdown reduces lipopolysaccharide-induced cell viability and expression of inflammation-associated genes in gastric cancer cells in vitro and in nude mouse xenografts." in: Molecular medicine reports, Vol. 12, Issue 3, pp. 4332-9, 2015
de Jesus, Spadacci-Morena, dos Anjos Rabelo, Pinfildi, Fukuda, Plapler: "Low-level laser therapy in IL-1β, COX-2, and PGE2 modulation in partially injured Achilles tendon." in: Lasers in medical science, Vol. 30, Issue 1, pp. 153-8, 2015
Bagriyanik, Ersoy, Cetinkaya, Ikizoglu, Kutri, Ozcana, Kamanga, Kiray: "The effects of resveratrol on chronic constriction injury of sciatic nerve in rats." in: Neuroscience letters, Vol. 561, pp. 123-7, 2014
Zhong, Shu, Wang, Luo, Zhong, Ran, Zheng, Yin, Ling: "Enhanced homing of mesenchymal stem cells to the ischemic myocardium by ultrasound-targeted microbubble destruction." in: Ultrasonics, Vol. 52, Issue 2, pp. 281-6, 2011
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