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|Antigen||Interleukin 1 Receptor Antagonist (IL1RN) Antibodies|
|Epitope||AA 27-178 Alternatives|
|Reactivity||Mouse (Murine) Alternatives|
|Conjugate||This IL1RN antibody is un-conjugated Alternatives|
ELISA, Western Blotting (WB)
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Product Details anti-IL1RN AntibodyTarget Details IL1RN Application Details Handling Images
|Purpose||Rabbit IgG polyclonal antibody for Interleukin-1 receptor antagonist protein(Il1rn) detection. Tested with WB, ELISA in Mouse.|
|Cross-Reactivity (Details)||No cross reactivity with other proteins.|
Rabbit IgG polyclonal antibody for Interleukin-1 receptor antagonist protein(Il1rn) detection. Tested with WB, ELISA in Mouse.
Gene Name: interleukin 1 receptor antagonist
Protein Name: Interleukin-1 receptor antagonist protein
|Purification||Immunogen affinity purified.|
|Immunogen||E. coli-derived mouse IL1RA recombinant protein (Position: R27-Q178). Mouse IL1RA shares 77% and 90.7% amino acid (aa) sequence identity with human and rat IL1RA, respectively.|
Target Details IL1RNProduct Details anti-IL1RN Antibody Application Details Handling Images back to top
|Alternative Name||Il1rn (IL1RN Antibody Abstract)|
The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene. The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Synonyms: Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, IL1 inhibitor, Il1rn, Il-1ra
|Pathways||NF-kappaB Signaling, Hormone Transport|
Application DetailsProduct Details anti-IL1RN Antibody Target Details IL1RN Handling Images back to top
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL1RN Antibody Target Details IL1RN Application Details Images back to top
|Reconstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C,-20 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.