anti-Cow (Bovine) Insulin antibody for Immunohistochemistry

Recommended Insulin Antibody (supplied by: Log in to see )

Antigen
Insulin (INS) Antibodies
  • ins1
  • xins
  • ins1-a
  • Insulin
  • IDDM2
  • ILPR
  • IRDN
  • MODY10
  • AA986540
  • Ins-2
  • InsII
  • Mody
  • Mody4
  • proinsulin
  • zgc:109842
  • insulin
  • insulin precursor
  • insulin II
  • preproinsulin
  • ins
  • PIN
  • INS
  • Ins
  • INS-IGF2
  • Ins2
Reactivity
Buffalo (Bubalus), Chicken, Cow (Bovine), Horse (Equine), Human, Lizard, Macaque, Monkey, Moth, Mouse (Murine), Pig (Porcine), Rat (Rattus), Sheep (Ovine)
874
391
269
262
205
126
49
6
6
5
5
3
3
2
2
1
1
Host
Rabbit
707
181
51
16
3
1
Clonality
Polyclonal
Conjugate
This Insulin antibody is un-conjugated
46
38
37
23
22
22
22
17
17
14
14
14
14
14
14
14
14
10
9
8
8
8
5
5
5
5
5
5
2
1
Application
Immunoelectron Microscopy (IEM), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
501
373
237
227
192
181
145
122
66
64
32
26
15
11
7
6
5
4
4
3
2
1
1
1
1
1
1
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Catalog No. ABIN617877
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
9.34839 ABIN1804387 ELISA IHC IHC (fro) IHC (p) Mouse IgG1 Log in to see E2E3 0
9.34839 ABIN1804388 ELISA IHC IHC (fro) IHC (p) Mouse IgG1 Log in to see D3E7 (5B6-6) 0
9.34839 ABIN255726 IHC (fro) IHC (p) IHC ELISA Mouse IgG1 Log in to see D3E7 (5B6-6) 0
9.34839 ABIN2471478 IHC ELISA Mouse IgG1 Log in to see D3E7 0
1 ABIN768892 ELISA IHC IHC (fro) IHC (p) Mouse IgG1 Log in to see D3E7 0
1 ABIN260218 IHC (p) IHC ELISA Mouse IgG1 Log in to see 2D11 0
1 ABIN269653 DB ICC IF IHC (p) IHC RIA Mouse IgG1 Log in to see K36aC10 0
1 ABIN1172907 ICC IHC WB Rabbit IgG AA 25-54 Log in to see Polyclonal 0
1 ABIN1839876 IF IHC IHC (p) RIA Mouse IgG1 Log in to see K36aC10 0
1 ABIN206973 BR ELISA Func ICC IHC IHC (p) Neut RIA Mouse IgG1 Log in to see IN-05 0
1 ABIN2742155 ELISA FACS IF IHC IHC (p) IP WB Mouse IgG1, kappa AA 1-84 Log in to see 2D11-H5 or INS05 0
1 ABIN1839720 ELISA IHC IHC (fro) Mouse IgG1, kappa Log in to see D4B8 0
1 ABIN2610290 ELISA IHC IHC (p) Mouse IgG1 Log in to see 0
1 ABIN602181 IHC ELISA WB Mouse IgG1 Log in to see 0
1 ABIN201081 ELISA IHC IHC (fro) IHC (p) Mouse IgG1 Log in to see 0
1 ABIN1502407 IHC IHC (p) Mouse IgG1 Log in to see B453 0
1 ABIN2742157 FACS IF IHC IHC (p) IP WB Mouse IgG1, kappa AA 1-84 Log in to see E2-E3-2D11-H5 or INS04-INS05 0
1 ABIN2742156 ELISA FACS IF IHC IHC (p) IP WB Mouse IgG1, kappa AA 1-84 Log in to see E2-E3 or INS04 0
1 ABIN1959952 ELISA IHC IHC (fro) IHC (p) Mouse IgG1, kappa Log in to see D6C4 0
1 ABIN599761 IHC IHC (p) Mouse IgG1 Log in to see 0

General

Antigen Insulin (INS) Antibodies
Reactivity Buffalo (Bubalus), Chicken, Cow (Bovine), Horse (Equine), Human, Lizard, Macaque, Monkey, Moth, Mouse (Murine), Pig (Porcine), Rat (Rattus), Sheep (Ovine)
(874), (391), (269), (262), (205), (126), (49), (6), (6), (5), (5), (3), (3), (2), (2), (1), (1)
Host Rabbit
(707), (181), (51), (16), (3), (1)
Clonality
Polyclonal
Conjugate This Insulin antibody is un-conjugated
(46), (38), (37), (23), (22), (22), (22), (17), (17), (14), (14), (14), (14), (14), (14), (14), (14), (10), (9), (8), (8), (8), (5), (5), (5), (5), (5), (5), (2), (1)
Application Immunoelectron Microscopy (IEM), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
(501), (373), (237), (227), (192), (181), (145), (122), (66), (64), (32), (26), (15), (11), (7), (6), (5), (4), (4), (3), (2), (1), (1), (1), (1), (1), (1)
Pubmed 44 references available
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Product Details anti-Insulin Antibody

Target Details Insulin Application Details Handling References for anti-Insulin antibody (ABIN617877) Images
Cross-Reactivity Cow (Bovine), Pig (Porcine), Rat (Rattus)
Characteristics The Insulin antiserum was quality control tested using standard immunohistochemical methods. The antiserum demonstrates strongly positive labeling of rat pancreatic beta cells using indirect immunofluorescent and biotin/avidin-HRP techniques. Recommended primary dilutions for these methods are 1/500-1/1000 in PBS/0.3 % Triton X-100 - Cy3 Technique and 1/3000-1/5000 in PBS/0.3 % Triton X-100 - biotin/avidin-HRP Technique. Immuostaining is completely abolished by soluble pre-adsorption with bovine insulin at 10 μg per mL of diluted antiserum.
Purification Whole Serum
Immunogen Insulin
Isotype IgG

Target Details Insulin

Product Details anti-Insulin Antibody Application Details Handling References for anti-Insulin antibody (ABIN617877) Images back to top
Antigen
Alternative Name Insulin (INS Antibody Abstract)
Gene ID 397415, 280829
Pathways NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation

Application Details

Product Details anti-Insulin Antibody Target Details Insulin Handling References for anti-Insulin antibody (ABIN617877) Images back to top
Restrictions For Research Use only

Handling

Product Details anti-Insulin Antibody Target Details Insulin Application Details References for anti-Insulin antibody (ABIN617877) Images back to top
Format Liquid
Buffer Contains ≤ 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment After reconstitution, use immediately or refrigerate at 2 - 8 °C up to 2 days. For long-term storage aliquot antibody and freeze at -15 °C or lower. Avoid repeated freeze/thaw cycles.

References for anti-Insulin antibody (ABIN617877)

Product Details anti-Insulin Antibody Target Details Insulin Application Details Handling Images back to top
Product cited in:

Nicol, Grant, Grant, Comstock, Nguyen, Smith, Grove, Marks: "Pancreatic inflammation and increased islet macrophages in insulin-resistant juvenile primates." in: The Journal of endocrinology, Vol. 217, Issue 2, pp. 207-13, 2013

Jung, Jung, Ramalingam, Yoon, Bae, Park: "Anti-diabetic effect of Wen-pi-tang-Hab-Wu-ling-san extract in streptozotocin-induced diabetic rats." in: Indian journal of pharmacology, Vol. 44, Issue 1, pp. 97-102, 2012

Hasegawa, Fukui, Hosoda, Asano, Harusato, Tanaka, Shiraishi, Senmaru, Sakabe, Yamasaki, Kitawaki, Fujinami, Ohta, Obayashi, Nakamura: "Telmisartan, an angiotensin II type 1 receptor blocker, prevents the development of diabetes in male Spontaneously Diabetic Torii rats." in: European journal of pharmacology, Vol. 605, Issue 1-3, pp. 164-9, 2009

Ravassard, Emilie Bricout-Neveu, Hazhouz, Pechberty, Mallet, Czernichow, Scharfmann: "A new strategy to generate functional insulin-producing cell lines by somatic gene transfer into pancreatic progenitors." in: PLoS ONE, Vol. 4, Issue 3, pp. e4731, 2009

Du, Klimstra, Varmus: "Activation of PyMT in beta cells induces irreversible hyperplasia, but oncogene-dependent acinar cell carcinomas when activated in pancreatic progenitors." in: PLoS ONE, Vol. 4, Issue 9, pp. e6932, 2009

Danilova, Tai, Mele, Beinborn, Leiter, Greenberg, Perfield, Defuria, Singru, Lechan, Huber: "Neurogenin 3-specific dipeptidyl peptidase-2 deficiency causes impaired glucose tolerance, insulin resistance, and visceral obesity." in: Endocrinology, Vol. 150, Issue 12, pp. 5240-8, 2009

Heart, Cline, Collis, Pongratz, Gray, Smith: "Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion." in: American journal of physiology. Endocrinology and metabolism, Vol. 296, Issue 6, pp. E1354-62, 2009

Lacroix, Badonnel, Meunier, Tan, Schlegel-Le Poupon, Durieux, Monnerie, Baly, Congar, Salesse, Caillol: "Expression of insulin system in the olfactory epithelium: first approaches to its role and regulation." in: Journal of neuroendocrinology, Vol. 20, Issue 10, pp. 1176-90, 2008

Yasuda, Yamamoto, Ochiai, Eguchi, Arishima: "Effects of growth factors on development of fetal islet B-cells in vitro." in: The Journal of veterinary medical science / the Japanese Society of Veterinary Science, Vol. 69, Issue 8, pp. 807-11, 2007

Duvillié, Heinis, Stetsyuk: "In vivo and in vitro techniques to study pancreas development and islet cell function." in: Endocrine development, Vol. 12, pp. 46-54, 2007

Du, Lewis, Hanahan, Varmus: "Assessing tumor progression factors by somatic gene transfer into a mouse model: Bcl-xL promotes islet tumor cell invasion." in: PLoS biology, Vol. 5, Issue 10, pp. e276, 2007

Ku, Lee: "The distribution and frequency of endocrine cells in the splenic lobe of grass lizard (Takydromus wolteri). An immunohistochemical study." in: European journal of histochemistry : EJH, Vol. 48, Issue 4, pp. 429-36, 2005

Castaing, Guerci, Mallet, Czernichow, Ravassard, Scharfmann: "Efficient restricted gene expression in beta cells by lentivirus-mediated gene transfer into pancreatic stem/progenitor cells." in: Diabetologia, Vol. 48, Issue 4, pp. 709-19, 2005

Yamamoto, Yasuda, Hori, Arishima, Eguchi: "Recovery in the fetal pancreatic islet following fetal administration of streptozotocin in the rat in vivo and in vitro." in: The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology, Vol. 281, Issue 2, pp. 1319-25, 2004

Zhang, Davenport, Croyle, Haycraft, Yoder: "Disruption of IFT results in both exocrine and endocrine abnormalities in the pancreas of Tg737(orpk) mutant mice." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 85, Issue 1, pp. 45-64, 2004

Ku, Lee, Lee: "Immunohistochemical study of the pancreatic endocrine cells in the BALB/c mice: an unique distributional pattern of glucagon." in: Journal of veterinary science, Vol. 3, Issue 3, pp. 167-73, 2003

Duvillié, Attali, Aiello, Quemeneur, Scharfmann: "Label-retaining cells in the rat pancreas: location and differentiation potential in vitro." in: Diabetes, Vol. 52, Issue 8, pp. 2035-42, 2003

Lewis, Klimstra, Varmus: "The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer." in: Genes & development, Vol. 17, Issue 24, pp. 3127-38, 2003

Page, du Toit, Muller, Mattysen, Lyners: "An immunocytochemical profile of the endocrine pancreas using an occlusive duct ligation model." in: JOP : Journal of the pancreas, Vol. 1, Issue 4, pp. 191-203, 2002

Elghazi, Cras-Méneur, Czernichow, Scharfmann: "Role for FGFR2IIIb-mediated signals in controlling pancreatic endocrine progenitor cell proliferation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 6, pp. 3884-9, 2002

Images

Product Details anti-Insulin Antibody Target Details Insulin Application Details Handling References for anti-Insulin antibody (ABIN617877) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Insulin (INS) antibody (ABIN617877) IHC image of beta cells in islets of Langerhans of rat pancreas