anti-Rat (Rattus) Insulin antibody for Immunohistochemistry

Recommended Insulin Antibody

Antigen
Insulin (INS) Antibodies
  • ins1
  • xins
  • ins1-a
  • Insulin
  • IDDM2
  • ILPR
  • IRDN
  • MODY10
  • AA986540
  • Ins-2
  • InsII
  • Mody
  • Mody4
  • proinsulin
  • zgc:109842
  • insulin
  • insulin precursor
  • insulin II
  • preproinsulin
  • ins
  • PIN
  • INS
  • Ins
  • INS-IGF2
  • Ins2
Reactivity
Buffalo (Bubalus), Chicken, Cow (Bovine), Horse (Equine), Human, Lizard, Macaque, Monkey, Moth, Mouse (Murine), Pig (Porcine), Rat (Rattus), Sheep (Ovine)
718
275
246
220
198
108
9
8
6
6
6
4
3
2
2
2
2
2
2
1
1
1
1
Host
Rabbit
539
213
50
4
2
1
Clonality
Polyclonal
Conjugate
This Insulin antibody is un-conjugated
39
29
24
15
13
13
8
8
8
8
8
8
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
2
1
Application
Immunoelectron Microscopy (IEM), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
335
227
193
166
158
127
107
66
57
33
30
30
23
21
21
7
5
4
4
4
3
2
2
2
1
1
1
1
1
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Available images

Catalog No. ABIN617877
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
22.0936 ABIN1873240 IHC WB Rabbit IgG Polyclonal 0
21.049648 ABIN3022885 IHC WB Rabbit IgG Polyclonal 1
19.0936 ABIN4904068 ICC IF IHC Rabbit IgG 0
16 ABIN5997014 IF/ICC IHC Rabbit IgG 0
13.549647 ABIN3185194 ELISA IHC Rabbit IgG Internal Region Polyclonal 0
10.093599 ABIN1804388 ELISA IHC IHC (fro) IHC (p) Mouse IgG1 D3E7 (5B6-6) 0
10.093599 ABIN768892 ELISA IHC IHC (fro) IHC (p) Mouse IgG1 D3E7 0
10.093599 ABIN396953 IHC IHC (p) Mouse IgG1, kappa 0
10.093599 ABIN6262598 ELISA IHC WB Rabbit IgG Polyclonal 0
10.093599 ABIN337249 FACS ICC IF IHC IHC (p) Rabbit IgG Polyclonal 0
10.093599 ABIN609715 IHC IHC (p) Mouse INS04-INS05 0
10 ABIN1868717 ICC IHC WB Rabbit IgG AA 25-110 Polyclonal 0
10 ABIN2934882 IF/ICC IHC IP WB Rabbit AA 25-110 Polyclonal 0
8.5 ABIN6673370 IHC WB Rabbit IgG Polyclonal 1
7.0935993 ABIN1959952 ELISA IHC IHC (fro) IHC (p) Mouse IgG1, kappa D6C4 0
7.0935993 ABIN2471478 IHC ELISA Mouse IgG1 D3E7 0
7 ABIN6262605 ELISA ICC IF IHC WB Rabbit IgG Polyclonal 0
4 ABIN6713283 IHC WB Rabbit AA 11-60 Polyclonal 0
1 ABIN599763 IHC IHC (p) Mouse IgG1 0
1 ABIN1453515 IHC ELISA Rabbit IgG AA 49-98 Polyclonal 0

General

Antigen Insulin (INS) Antibodies
Reactivity Buffalo (Bubalus), Chicken, Cow (Bovine), Horse (Equine), Human, Lizard, Macaque, Monkey, Moth, Mouse (Murine), Pig (Porcine), Rat (Rattus), Sheep (Ovine)
(718), (275), (246), (220), (198), (108), (9), (8), (6), (6), (6), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Host Rabbit
(539), (213), (50), (4), (2), (1)
Clonality
Polyclonal
Conjugate This Insulin antibody is un-conjugated
(39), (29), (24), (15), (13), (13), (8), (8), (8), (8), (8), (8), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (2), (1)
Application Immunoelectron Microscopy (IEM), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
(335), (227), (193), (166), (158), (127), (107), (66), (57), (33), (30), (30), (23), (21), (21), (7), (5), (4), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 45 references available
Supplier

Product Details anti-Insulin Antibody

Target Details Insulin Application Details Handling References for anti-Insulin antibody (ABIN617877) Images
Cross-Reactivity Cow (Bovine), Pig (Porcine), Rat (Rattus)
Characteristics The Insulin antiserum was quality control tested using standard immunohistochemical methods. The antiserum demonstrates strongly positive labeling of rat pancreatic beta cells using indirect immunofluorescent and biotin/avidin-HRP techniques. Recommended primary dilutions for these methods are 1/500-1/1000 in PBS/0.3 % Triton X-100 - Cy3 Technique and 1/3000-1/5000 in PBS/0.3 % Triton X-100 - biotin/avidin-HRP Technique. Immuostaining is completely abolished by soluble pre-adsorption with bovine insulin at 10 μg per mL of diluted antiserum.
Purification Whole Serum
Immunogen Insulin
Isotype IgG
Plasmids, Primers & others

Target Details Insulin

Product Details anti-Insulin Antibody Application Details Handling References for anti-Insulin antibody (ABIN617877) Images back to top
Antigen
Alternative Name Insulin (INS Antibody Abstract)
Gene ID 397415, 280829
Pathways NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation

Application Details

Product Details anti-Insulin Antibody Target Details Insulin Handling References for anti-Insulin antibody (ABIN617877) Images back to top
Restrictions For Research Use only

Handling

Product Details anti-Insulin Antibody Target Details Insulin Application Details References for anti-Insulin antibody (ABIN617877) Images back to top
Format Liquid
Buffer Contains ≤ 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment After reconstitution, use immediately or refrigerate at 2 - 8 °C up to 2 days. For long-term storage aliquot antibody and freeze at -15 °C or lower. Avoid repeated freeze/thaw cycles.

References for anti-Insulin antibody (ABIN617877)

Product Details anti-Insulin Antibody Target Details Insulin Application Details Handling Images back to top
Product cited in:

Nicol, OBrien, Dumesic, Grogan, Tarantal, Abbott: "Abnormal infant islet morphology precedes insulin resistance in PCOS-like monkeys." in: PLoS ONE, Vol. 9, Issue 9, pp. e106527, 2015

Nicol, Grant, Grant, Comstock, Nguyen, Smith, Grove, Marks: "Pancreatic inflammation and increased islet macrophages in insulin-resistant juvenile primates." in: The Journal of endocrinology, Vol. 217, Issue 2, pp. 207-13, 2013

Jung, Jung, Ramalingam, Yoon, Bae, Park: "Anti-diabetic effect of Wen-pi-tang-Hab-Wu-ling-san extract in streptozotocin-induced diabetic rats." in: Indian journal of pharmacology, Vol. 44, Issue 1, pp. 97-102, 2012

Hasegawa, Fukui, Hosoda, Asano, Harusato, Tanaka, Shiraishi, Senmaru, Sakabe, Yamasaki, Kitawaki, Fujinami, Ohta, Obayashi, Nakamura: "Telmisartan, an angiotensin II type 1 receptor blocker, prevents the development of diabetes in male Spontaneously Diabetic Torii rats." in: European journal of pharmacology, Vol. 605, Issue 1-3, pp. 164-9, 2009

Ravassard, Emilie Bricout-Neveu, Hazhouz, Pechberty, Mallet, Czernichow, Scharfmann: "A new strategy to generate functional insulin-producing cell lines by somatic gene transfer into pancreatic progenitors." in: PLoS ONE, Vol. 4, Issue 3, pp. e4731, 2009

Du, Klimstra, Varmus: "Activation of PyMT in beta cells induces irreversible hyperplasia, but oncogene-dependent acinar cell carcinomas when activated in pancreatic progenitors." in: PLoS ONE, Vol. 4, Issue 9, pp. e6932, 2009

Danilova, Tai, Mele, Beinborn, Leiter, Greenberg, Perfield, Defuria, Singru, Lechan, Huber: "Neurogenin 3-specific dipeptidyl peptidase-2 deficiency causes impaired glucose tolerance, insulin resistance, and visceral obesity." in: Endocrinology, Vol. 150, Issue 12, pp. 5240-8, 2009

Heart, Cline, Collis, Pongratz, Gray, Smith: "Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion." in: American journal of physiology. Endocrinology and metabolism, Vol. 296, Issue 6, pp. E1354-62, 2009

Lacroix, Badonnel, Meunier, Tan, Schlegel-Le Poupon, Durieux, Monnerie, Baly, Congar, Salesse, Caillol: "Expression of insulin system in the olfactory epithelium: first approaches to its role and regulation." in: Journal of neuroendocrinology, Vol. 20, Issue 10, pp. 1176-90, 2008

Yasuda, Yamamoto, Ochiai, Eguchi, Arishima: "Effects of growth factors on development of fetal islet B-cells in vitro." in: The Journal of veterinary medical science / the Japanese Society of Veterinary Science, Vol. 69, Issue 8, pp. 807-11, 2007

Duvillié, Heinis, Stetsyuk: "In vivo and in vitro techniques to study pancreas development and islet cell function." in: Endocrine development, Vol. 12, pp. 46-54, 2007

Du, Lewis, Hanahan, Varmus: "Assessing tumor progression factors by somatic gene transfer into a mouse model: Bcl-xL promotes islet tumor cell invasion." in: PLoS biology, Vol. 5, Issue 10, pp. e276, 2007

Ku, Lee: "The distribution and frequency of endocrine cells in the splenic lobe of grass lizard (Takydromus wolteri). An immunohistochemical study." in: European journal of histochemistry : EJH, Vol. 48, Issue 4, pp. 429-36, 2005

Castaing, Guerci, Mallet, Czernichow, Ravassard, Scharfmann: "Efficient restricted gene expression in beta cells by lentivirus-mediated gene transfer into pancreatic stem/progenitor cells." in: Diabetologia, Vol. 48, Issue 4, pp. 709-19, 2005

Yamamoto, Yasuda, Hori, Arishima, Eguchi: "Recovery in the fetal pancreatic islet following fetal administration of streptozotocin in the rat in vivo and in vitro." in: The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology, Vol. 281, Issue 2, pp. 1319-25, 2004

Zhang, Davenport, Croyle, Haycraft, Yoder: "Disruption of IFT results in both exocrine and endocrine abnormalities in the pancreas of Tg737(orpk) mutant mice." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 85, Issue 1, pp. 45-64, 2004

Ku, Lee, Lee: "Immunohistochemical study of the pancreatic endocrine cells in the BALB/c mice: an unique distributional pattern of glucagon." in: Journal of veterinary science, Vol. 3, Issue 3, pp. 167-73, 2003

Duvillié, Attali, Aiello, Quemeneur, Scharfmann: "Label-retaining cells in the rat pancreas: location and differentiation potential in vitro." in: Diabetes, Vol. 52, Issue 8, pp. 2035-42, 2003

Lewis, Klimstra, Varmus: "The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer." in: Genes & development, Vol. 17, Issue 24, pp. 3127-38, 2003

Page, du Toit, Muller, Mattysen, Lyners: "An immunocytochemical profile of the endocrine pancreas using an occlusive duct ligation model." in: JOP : Journal of the pancreas, Vol. 1, Issue 4, pp. 191-203, 2002

Images

Product Details anti-Insulin Antibody Target Details Insulin Application Details Handling References for anti-Insulin antibody (ABIN617877) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Insulin (INS) antibody (ABIN617877) IHC image of beta cells in islets of Langerhans of rat pancreas