anti-Horse (Equine) Insulin Receptor antibody for Immunohistochemistry

Recommended Insulin Receptor Antibody (supplied by: Log in to see )

Antigen
Insulin Receptor (INSR) Antibodies
  • CD220
  • HHF5
  • 4932439J01Rik
  • D630014A15Rik
  • IR
  • IR-A
  • IR-B
  • 18402
  • CG18402
  • DIHR
  • DILR
  • DIR
  • DIRH
  • DIRbeta
  • DInR
  • DInr
  • Dir-a
  • Dir-b
  • Dmel\\CG18402
  • INR
  • INS
  • Inr
  • Inr-alpha
  • Inr-beta
  • InsR
  • dINR
  • dIR
  • dIRH
  • dInR
  • dInr
  • dInsR
  • dinr
  • dir
  • er10
  • inr
  • insulin/insulin-like growth factor receptor
  • l(3)05545
  • l(3)93Dj
  • l(3)er10
  • lnR
  • ir-A
  • CTK-1
  • ir
  • INSR
  • NV14476
  • cd220
  • hhf5
  • insulin receptor
  • Insulin-like receptor
  • insulin receptor L homeolog
  • INSR
  • Insr
  • InR
  • LOC100122567
  • LOC100451802
  • insr.L
Epitope
Middle Region
33
30
21
20
17
17
12
11
10
9
8
8
7
7
7
6
6
5
5
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
348
141
106
25
21
16
15
13
13
8
5
4
3
1
1
1
1
1
Host
Rabbit
281
97
6
1
1
Clonality
Polyclonal
Conjugate
This Insulin Receptor antibody is un-conjugated
25
23
14
12
11
9
6
5
5
4
4
4
4
3
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
240
134
113
50
49
46
18
17
13
11
11
8
7
4
3
2
2
2
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN2776774
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
8.672457 ABIN2792204 IHC WB Rabbit Middle Region Log in to see Polyclonal 1
1 ABIN604778 IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal 0
1 ABIN599777 IHC IHC (p) WB Rabbit AA 59-75 Log in to see Polyclonal 0

General

Antigen Insulin Receptor (INSR) Antibodies
Epitope Middle Region
(33), (30), (21), (20), (17), (17), (12), (11), (10), (9), (8), (8), (7), (7), (7), (6), (6), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
(348), (141), (106), (25), (21), (16), (15), (13), (13), (8), (5), (4), (3), (1), (1), (1), (1), (1)
Host Rabbit
(281), (97), (6), (1), (1)
Clonality
Polyclonal
Conjugate This Insulin Receptor antibody is un-conjugated
(25), (23), (14), (12), (11), (9), (6), (5), (5), (4), (4), (4), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(240), (134), (113), (50), (49), (46), (18), (17), (13), (11), (11), (8), (7), (4), (3), (2), (2), (2), (1), (1)
Pubmed 1 reference available
Supplier Log in to see

Product Details anti-Insulin Receptor Antibody

Target Details Insulin Receptor Application Details Handling References for anti-Insulin Receptor antibody (ABIN2776774) Images
Blocking Peptide Blocking peptide for this product available: ABIN978574
Sequence ENNVVHLMWQ EPKEPNGLIV LYEVSYRRYG DEELHLCVSR KHFALERGCR
Predicted Reactivity Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against INSR. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human INSR
Plasmids, Primers & others

Target Details Insulin Receptor

Product Details anti-Insulin Receptor Antibody Application Details Handling References for anti-Insulin Receptor antibody (ABIN2776774) Images back to top
Antigen
Alternative Name INSR (INSR Antibody Abstract)
Background This receptor binds insulin and has a tyrosine-protein kinase activity. Isoform Short has a higher affinity for insulin. INSR mediates the metabolic functions of insulin. INSR binding to insulin stimulates association of the receptor with downstream media
Alias Symbols: CD220, HHF5
Protein Interaction Partner: KRT31, UBC, ARRB2, MOK, Grb2, Hgf, DOK1, SH2B1, Stat5b, TEAD1, STAT5A, JAK2, JAK1, IRS1, IRF7, PLCG1, GRB10, Socs6, Socs1, SOCS3, SH2B2, HGS, INPPL1, Calmodulin, Mad2l1, KRT27, DOK5, DOK4, SNX6, SNX4, SNX2, ACP1, PTPN2, SYNCRIP, FRS2, PIK3R3, VAV3, ARHGAP
Protein Size: 1382
Molecular Weight 154 kDa
Gene ID 3643
NCBI Accession NM_000208, NP_000199
UniProt P06213
Pathways NF-kappaB Signaling, RTK Signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity

Application Details

Product Details anti-Insulin Receptor Antibody Target Details Insulin Receptor Handling References for anti-Insulin Receptor antibody (ABIN2776774) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1382 AA

Restrictions For Research Use only

Handling

Product Details anti-Insulin Receptor Antibody Target Details Insulin Receptor Application Details References for anti-Insulin Receptor antibody (ABIN2776774) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Insulin Receptor antibody (ABIN2776774)

Product Details anti-Insulin Receptor Antibody Target Details Insulin Receptor Application Details Handling Images back to top
Background publications

Netzer, Freudenberg, Heinze, Heinze-Kuhn, Goebel, McCarthy, Roses, Göbel, Todt, Kubisch: "Replication study of the insulin receptor gene in migraine with aura." in: Genomics, Vol. 91, Issue 6, pp. 503-7, 2008

Images

Product Details anti-Insulin Receptor Antibody Target Details Insulin Receptor Application Details Handling References for anti-Insulin Receptor antibody (ABIN2776774) back to top
Supplier Images
Western Blotting (WB) image for anti-Insulin Receptor (INSR) (Middle Region) antibody (ABIN2776774) WB Suggested Anti-INSR Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Posi...
Immunohistochemistry (IHC) image for anti-Insulin Receptor (INSR) (Middle Region) antibody (ABIN2776774) Rabbit Anti-INSR Antibody Formalin Fixed Paraffin Embedded Tissue: Human Heart Tiss...
Immunohistochemistry (IHC) image for anti-Insulin Receptor (INSR) (Middle Region) antibody (ABIN2776774) Rabbit Anti-INSR Antibody Formalin Fixed Paraffin Embedded Tissue: Human heart Tiss...