anti-Human Insulin Receptor antibody for Neutralization

Recommended Insulin Receptor Antibody (supplied by: Log in to see )

Antigen
Insulin Receptor (INSR) Antibodies
  • CD220
  • HHF5
  • 4932439J01Rik
  • D630014A15Rik
  • IR
  • IR-A
  • IR-B
  • 18402
  • CG18402
  • DIHR
  • DILR
  • DIR
  • DIRH
  • DIRbeta
  • DInR
  • DInr
  • Dir-a
  • Dir-b
  • Dmel\\CG18402
  • INR
  • INS
  • Inr
  • Inr-alpha
  • Inr-beta
  • InsR
  • dINR
  • dIR
  • dIRH
  • dInR
  • dInr
  • dInsR
  • dinr
  • dir
  • er10
  • inr
  • insulin/insulin-like growth factor receptor
  • l(3)05545
  • l(3)93Dj
  • l(3)er10
  • lnR
  • ir-A
  • CTK-1
  • ir
  • INSR
  • NV14476
  • cd220
  • hhf5
  • insulin receptor
  • Insulin-like receptor
  • insulin receptor L homeolog
  • INSR
  • Insr
  • InR
  • LOC100122567
  • LOC100451802
  • insr.L
Epitope
pTyr1162, pTyr1163
40
34
22
22
17
14
12
10
9
8
8
7
6
6
6
5
5
5
5
5
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
326
128
96
23
23
21
20
17
17
9
5
5
3
1
1
1
1
1
Host
Rabbit
251
100
8
1
1
Clonality
Polyclonal
Conjugate
This Insulin Receptor antibody is un-conjugated
26
18
12
11
10
9
6
5
5
5
4
4
4
1
1
1
1
1
1
1
1
1
1
1
Application
Blocking Peptide (BP), Neutralization (Neut), Western Blotting (WB)
220
144
75
52
47
45
17
13
13
12
11
8
7
7
4
3
2
2
Supplier
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Catalog No. ABIN5665635
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN228603 Neut Mouse IgG1 Log in to see 47-9 0
1 ABIN1721814 IP Neut ELISA Mouse IgG2b Log in to see MA-20 0
1 ABIN1722146 IP Neut ELISA WB HRP Mouse IgG2b Log in to see MA-20 0
1 ABIN1722143 IP Neut ELISA WB Biotin Mouse IgG2b Log in to see MA-20 0
1 ABIN1722144 IP Neut ELISA WB DyLight 650 Mouse IgG2b Log in to see MA-20 0
1 ABIN1722145 IP Neut ELISA WB DyLight 488 Mouse IgG2b Log in to see MA-20 0
1 ABIN1722147 IP Neut ELISA WB DyLight 550 Mouse IgG2b Log in to see MA-20 0

General

Antigen Insulin Receptor (INSR) Antibodies
Epitope pTyr1162, pTyr1163
(40), (34), (22), (22), (17), (14), (12), (10), (9), (8), (8), (7), (6), (6), (6), (5), (5), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(326), (128), (96), (23), (23), (21), (20), (17), (17), (9), (5), (5), (3), (1), (1), (1), (1), (1)
Host Rabbit
(251), (100), (8), (1), (1)
Clonality
Polyclonal
Conjugate This Insulin Receptor antibody is un-conjugated
(26), (18), (12), (11), (10), (9), (6), (5), (5), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Blocking Peptide (BP), Neutralization (Neut), Western Blotting (WB)
(220), (144), (75), (52), (47), (45), (17), (13), (13), (12), (11), (8), (7), (7), (4), (3), (2), (2)
Pubmed 1 reference available
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Product Details anti-Insulin Receptor Antibody

Target Details Insulin Receptor Application Details Handling References for anti-Insulin Receptor antibody (ABIN5665635) Images
Specificity Although exhibiting a preference for IR/IGF-1R, this has been shown by both peptide competition and protein blotting to react with other dual phosphotyrosine motifs from proteins such as c-Met and Shc.
Purification Immunogen affinity purified
Immunogen Synthetic phosphopeptide derived from the region of Insulin Receptor/IGF1R that contains tyrosines 1162 and 1163. The corresponding residues in the IGF1R are 1135 and 1136.

Target Details Insulin Receptor

Product Details anti-Insulin Receptor Antibody Application Details Handling References for anti-Insulin Receptor antibody (ABIN5665635) Images back to top
Antigen
Alternative Name Insulin R/CD220 (INSR Antibody Abstract)
Background Gene Symbol: INSR
Gene ID 3643
Pathways NF-kappaB Signaling, RTK Signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity

Application Details

Product Details anti-Insulin Receptor Antibody Target Details Insulin Receptor Handling References for anti-Insulin Receptor antibody (ABIN5665635) Images back to top
Application Notes Western Blot 1/1000., Blocking/NeutralizingThis antibody can be used in western blot, where a band of approximately 120 kDa is detected. Previous lots of this antibody have been used in immunostaining.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only

Handling

Product Details anti-Insulin Receptor Antibody Target Details Insulin Receptor Application Details References for anti-Insulin Receptor antibody (ABIN5665635) Images back to top
Format Liquid
Concentration 1.0 mg/mL
Buffer Dulbecco's PBS ( pH 7.3), 1.0 mg/mL and 50 % Glycerol
Buffer contains: 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C,-80 °C
Storage Comment Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

References for anti-Insulin Receptor antibody (ABIN5665635)

Product Details anti-Insulin Receptor Antibody Target Details Insulin Receptor Application Details Handling Images back to top
Product cited in:

Moteki, Shimamura, Kimura, Ogihara: "Signal transduction pathway for L-ascorbic acid- and L-ascorbic acid 2-glucoside-induced DNA synthesis and cell proliferation in primary cultures of adult rat hepatocytes." in: European journal of pharmacology, Vol. 683, Issue 1-3, pp. 276-84, 2012 Method employed by authors: Neutralization (Neut) (Sample species: Rat (Rattus)).

Images

Product Details anti-Insulin Receptor Antibody Target Details Insulin Receptor Application Details Handling References for anti-Insulin Receptor antibody (ABIN5665635) back to top
Supplier Images
 image for anti-Insulin Receptor (INSR) (pTyr1162), (pTyr1163) antibody (ABIN5665635) Peptide Competition Extracts prepared from CHO-T cells transfected with an insulin re...