anti-Human Integrin beta 2 antibody for Blocking Reagent

Recommended Integrin beta 2 Antibody (supplied by: Log in to see )

Antigen
Integrin beta 2 (ITGB2) Antibodies
  • CD18
  • LAD
  • LCAMB
  • LFA-1
  • MAC-1
  • MF17
  • MFI7
  • 2E6
  • AI528527
  • Cd18
  • Lfa1
  • ITGB2
  • itgb2
  • itgb2-a
  • itgb2-b
  • integrin subunit beta 2
  • integrin beta 2
  • integrin subunit beta 2 S homeolog
  • ITGB2
  • Itgb2
  • itgb2.S
Epitope
AA 23-700
46
36
28
22
16
15
13
12
10
7
6
5
5
5
5
5
5
4
4
4
4
3
3
3
3
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
519
212
121
40
38
23
22
13
5
4
3
3
3
3
3
2
1
1
Host
Goat
395
174
157
10
3
1
Clonality
Polyclonal
Conjugate
This Integrin beta 2 antibody is un-conjugated
84
74
53
29
14
12
11
10
8
8
7
7
6
6
6
6
6
6
6
5
5
3
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Blocking Reagent (BR), Flow Cytometry (FACS), Immunocytochemistry (ICC), Western Blotting (WB)
503
294
192
180
102
90
80
75
64
40
27
15
13
11
7
6
4
1
1
1
1
1
1
1
1
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Catalog No. ABIN5012937
Contact our Customer Service for availability and price in your country.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN206735 BR FACS IHC IHC (fro) IP Biotin Rat IgG2b Log in to see 0
1 ABIN576530 BR FACS IHC IHC (fro) IP PE Rat IgG2b Log in to see 0
1 ABIN206736 BR FACS IHC IHC (fro) IP Rat IgG2b Log in to see YFC118-3 0
1 ABIN1820130 BR FACS Func IHC IHC (fro) IP Rat IgG2b Log in to see YFC118-3 0
1 ABIN217662 BR FACS IHC IHC (fro) IP FITC Rat IgG2b Log in to see 0

General

Antigen Integrin beta 2 (ITGB2) Antibodies
Epitope AA 23-700
(46), (36), (28), (22), (16), (15), (13), (12), (10), (7), (6), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(519), (212), (121), (40), (38), (23), (22), (13), (5), (4), (3), (3), (3), (3), (3), (2), (1), (1)
Host Goat
(395), (174), (157), (10), (3), (1)
Clonality
Polyclonal
Conjugate This Integrin beta 2 antibody is un-conjugated
(84), (74), (53), (29), (14), (12), (11), (10), (8), (8), (7), (7), (6), (6), (6), (6), (6), (6), (6), (5), (5), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Blocking Reagent (BR), Flow Cytometry (FACS), Immunocytochemistry (ICC), Western Blotting (WB)
(503), (294), (192), (180), (102), (90), (80), (75), (64), (40), (27), (15), (13), (11), (7), (6), (4), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-Integrin beta 2 Antibody

Target Details Integrin beta 2 Application Details Handling References for anti-Integrin beta 2 antibody (ABIN5012937) Images
Specificity Detects human Integrin beta 2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 5 % cross-reactivity with recombinant human (rh) Integrin beta 1, rhIntegrin beta 3, and recombinant mouse Integrin beta 6 is observed.
Purification Immunogen affinity purified
Endotoxin Level <0.10 EU per 1 μg of the antibody by the LAL method.
Immunogen Mouse myeloma cell line NS0-derived recombinant human Integrin beta 2, Gln23-Asn700, Accession # AAA59490
Isotype IgG
Plasmids, Primers & others

Target Details Integrin beta 2

Product Details anti-Integrin beta 2 Antibody Application Details Handling References for anti-Integrin beta 2 antibody (ABIN5012937) Images back to top
Antigen
Alternative Name Integrin beta 2/CD18 (ITGB2 Antibody Abstract)
Background Alternative Names: 959 beta subunit precursor)10, CD18, CD18 antigen, CD18beta 2, cell surface adhesion glycoprotein (LFA-1, CR3, integrin beta-2, integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1,macrophage antigen 1 (mac-1) beta subunit), integrin, beta 2 (complement component 3 receptor 3 and 4 subunit), ITGB2, LAD, LCAMB, leukocyte cell adhesion molecule CD18, leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C, LFA-1, LFA-1 beta, MAC-1 beta, MF17, MFI7, P150, p150,95 beta
Gene ID 3689
Pathways NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation

Application Details

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Handling References for anti-Integrin beta 2 antibody (ABIN5012937) Images back to top
Application Notes Western Blot 0.1 μg/mL
Flow Cytometry 2.5 μg/10^6 cells
Adhesion Blockade
Immunocytochemistry 5-15 μg/mL
CyTOF-ready
Restrictions For Research Use only

Handling

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Application Details References for anti-Integrin beta 2 antibody (ABIN5012937) Images back to top
Reconstitution Reconstitute at 0.2 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months

References for anti-Integrin beta 2 antibody (ABIN5012937)

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Application Details Handling Images back to top
Product cited in:

Zhou, Zhao, Schwarz, Mangeat, Schwarz, Hamed, Bogeski, Helms, Rieger, Qu: "Bystander cells enhance NK cytotoxic efficiency by reducing search time." in: Scientific reports, Vol. 7, pp. 44357, 2017 Method employed by authors: Cellular Assay (CA) (Sample species: Human).

Smeekens, Gresnigt, Becker, Cheng, Netea, Jacobs, Jansen, van de Veerdonk, Williams, Joosten, Dinarello, Netea: "An anti-inflammatory property of Candida albicans β-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism." in: Cytokine, Vol. 71, Issue 2, pp. 215-22, 2015 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Dotterweich, Ebert, Kraus, Tower, Jakob, Schütze: "Mesenchymal stem cell contact promotes CCN1 splicing and transcription in myeloma cells." in: Cell communication and signaling : CCS, Vol. 12, pp. 36, 2014 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Jerke, Rolle, Dittmar, Bayat, Santoso, Sporbert, Luft, Kettritz: "Complement receptor Mac-1 is an adaptor for NB1 (CD177)-mediated PR3-ANCA neutrophil activation." in: The Journal of biological chemistry, Vol. 286, Issue 9, pp. 7070-81, 2011 Method employed by authors: Western Blotting (WB) (Sample species: Human).

van Grevenstein, Hofland, van Rossen, van Koetsveld, Jeekel, van Eijck: "Inflammatory cytokines stimulate the adhesion of colon carcinoma cells to mesothelial monolayers." in: Digestive diseases and sciences, Vol. 52, Issue 10, pp. 2775-83, 2007 Method employed by authors: Immunocytochemistry (ICC) (Sample species: Human).

Images

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Application Details Handling References for anti-Integrin beta 2 antibody (ABIN5012937) back to top
Supplier Images
Immunocytochemistry (ICC) image for anti-Integrin beta 2 (ITGB2) (AA 23-700) antibody (ABIN5012937) Integrin beta 2/CD18 in Human PBMCs. Integrin beta 2/CD18 was detected in immersion f...