anti-Rat (Rattus) Integrin beta 2 antibody for Blocking Reagent

Recommended Integrin beta 2 Antibody (supplied by: Log in to see )

Antigen
Integrin beta 2 (ITGB2) Antibodies
  • CD18
  • LAD
  • LCAMB
  • LFA-1
  • MAC-1
  • MF17
  • MFI7
  • 2E6
  • AI528527
  • Cd18
  • Lfa1
  • ITGB2
  • itgb2
  • itgb2-a
  • itgb2-b
  • integrin subunit beta 2
  • integrin beta 2
  • integrin subunit beta 2 S homeolog
  • ITGB2
  • Itgb2
  • itgb2.S
Reactivity
Rat (Rattus)
471
207
116
38
38
21
20
13
5
4
3
3
3
3
3
2
1
1
Host
Mouse
358
161
153
10
3
1
Clonality
Monoclonal
Conjugate
This Integrin beta 2 antibody is un-conjugated
82
72
50
27
14
11
10
8
8
8
7
6
6
6
6
6
6
5
5
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
Application
Blocking Reagent (BR), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc)), Immunoprecipitation (IP)
465
282
186
141
94
91
77
74
55
40
27
16
11
9
7
6
4
1
1
1
1
1
1
1
1
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Catalog No. ABIN2689034
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1177020 BR IHC (fro) FACS IHC (zinc) IP Mouse IgG1, kappa Log in to see WT-3 2

General

Antigen Integrin beta 2 (ITGB2) Antibodies
Reactivity Rat (Rattus)
(471), (207), (116), (38), (38), (21), (20), (13), (5), (4), (3), (3), (3), (3), (3), (2), (1), (1)
Host Mouse
(358), (161), (153), (10), (3), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Integrin beta 2 antibody is un-conjugated
(82), (72), (50), (27), (14), (11), (10), (8), (8), (8), (7), (6), (6), (6), (6), (6), (6), (5), (5), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Application Blocking Reagent (BR), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc)), Immunoprecipitation (IP)
(465), (282), (186), (141), (94), (91), (77), (74), (55), (40), (27), (16), (11), (9), (7), (6), (4), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-Integrin beta 2 Antibody

Target Details Integrin beta 2 Application Details Handling References for anti-Integrin beta 2 antibody (ABIN2689034) Images
Brand BD Pharmingen™
Characteristics The WT.3 antibody reacts with the 95-100 kDa β2 subunit (CD18), which is found on the majority of leukocytes as a heterodimer with any of the three distinct CD11 α integrin subunits (CD11a or αL, CD11b or αM, CD11c or αX) to form, respectively, LFA-1, Mac-1, and gp150, 95. The function-blocking activity of WT.3 antibody has been determined in several in vitro assays measuring the binding of LFA-1 (αLβ2 integrin) to ICAM-1 (CD54). It has also been reported that WT.3 mAb inhibits leukocyte infiltration in an in vivo system.

BD Pharmingen™ Purified Mouse Anti-Rat CD18 - Purified - Clone WT.3 - Isotype Mouse IgG1, κ - Reactivity Rat - 0.5 mg
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen PHA-stimulated rat splenocytes and rat thymic lymphoma FTL-43
Clone WT-3
Isotype IgG1, kappa

Target Details Integrin beta 2

Product Details anti-Integrin beta 2 Antibody Application Details Handling References for anti-Integrin beta 2 antibody (ABIN2689034) Images back to top
Antigen
Alternative Name CD18 (ITGB2 Antibody Abstract)
Background Synonyms: Integrin β2 chain
Pathways NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation

Application Details

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Handling References for anti-Integrin beta 2 antibody (ABIN2689034) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Application Details References for anti-Integrin beta 2 antibody (ABIN2689034) Images back to top
Concentration 0.5 mg/mL
Buffer Aqueous buffered solution containing ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store undiluted at 4°C.

References for anti-Integrin beta 2 antibody (ABIN2689034)

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Application Details Handling Images back to top
Product cited in:

Yamazaki, Seko, Tamatani, Miyasaka, Yagita, Okumura, Nagai, Yazaki: "Expression of intercellular adhesion molecule-1 in rat heart with ischemia/reperfusion and limitation of infarct size by treatment with antibodies against cell adhesion molecules." in: The American journal of pathology, Vol. 143, Issue 2, pp. 410-8, 1993

Tamatani, Kotani, Miyasaka: "Characterization of the rat leukocyte integrin, CD11/CD18, by the use of LFA-1 subunit-specific monoclonal antibodies." in: European journal of immunology, Vol. 21, Issue 3, pp. 627-33, 1991