anti-Mouse (Murine) MAP3K7 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended MAP3K7 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) Antibodies
  • si:ch211-225h9.1
  • zgc:110612
  • Tak1
  • MEKK7
  • TAK1
  • TGF1a
  • B430101B05
  • C87327
  • mitogen-activated protein kinase kinase kinase 7
  • mitogen activated protein kinase kinase kinase 7
  • map3k7
  • Map3k7
  • MAP3K7
Epitope
AA 563-579
35
20
14
13
11
10
10
10
8
7
6
4
4
4
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
200
81
67
5
5
4
4
4
3
3
3
2
2
1
1
1
1
Host
Rabbit
172
15
14
Clonality
Polyclonal
Conjugate
This MAP3K7 antibody is un-conjugated
10
10
10
9
9
9
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
161
127
73
39
19
8
5
5
4
1
1
1
Supplier
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Catalog No. ABIN615309
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13 ABIN462440 IHC IHC (p) WB Rabbit AA 563-579 Log in to see Polyclonal 0
11.497463 ABIN5611536 EIA IHC (p) WB Rabbit IgG Internal Region Log in to see Polyclonal 0
10 ABIN5534487 IHC (p) WB Rabbit Ig Fraction AA 131-160, N-Term Log in to see Polyclonal 0
10 ABIN1736722 IHC (p) WB Rabbit IgG AA 563-579 Log in to see Polyclonal 0
7 ABIN214285 IF IHC IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal 0
4 ABIN657840 IHC (p) WB Rabbit Ig Fraction AA 131-160, N-Term Log in to see Polyclonal 0
4 ABIN2878762 ELISA IHC IHC (p) WB Rabbit IgG AA 161-210 Log in to see Polyclonal 0
4 ABIN303015 IHC (p) WB Rabbit Log in to see Polyclonal 0
4 ABIN1736724 IHC (p) ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal 0
4 ABIN1736723 IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2887710 ELISA IHC IHC (p) WB Rabbit IgG AA 411-460 Log in to see Polyclonal 0
1 ABIN2884019 ELISA IHC IHC (p) WB Rabbit IgG pSer439 Log in to see Polyclonal 0
1 ABIN2893086 IHC IHC (p) WB Rabbit Asp181 Log in to see Polyclonal 0
1 ABIN2742744 IHC IHC (p) WB Rabbit Internal Region Log in to see Polyclonal 0
1 ABIN1811586 IHC IHC (p) WB Rabbit AA 131-160 Log in to see Polyclonal 0

General

Antigen Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) Antibodies
Epitope AA 563-579
(35), (20), (14), (13), (11), (10), (10), (10), (8), (7), (6), (4), (4), (4), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(200), (81), (67), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1)
Host Rabbit
(172), (15), (14)
Clonality
Polyclonal
Conjugate This MAP3K7 antibody is un-conjugated
(10), (10), (10), (9), (9), (9)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(161), (127), (73), (39), (19), (8), (5), (5), (4), (1), (1), (1)
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Product Details anti-MAP3K7 Antibody

Target Details MAP3K7 Application Details Handling Images
Specificity This antibody detects an ~70 kDa protein corresponding to the Apparent Molecular Mass of TAK1 on SDS-PAge Immunoblots.
Cross-Reactivity (Details) Species reactivity (expected):Bovine, Canine, Xenopus, Guinea pig, Hamster, Human, Monkey, Porcine, Rabbit, Rat, Sheep.
Species reactivity (tested):Mouse.
Purification Protein A Chromatography
Immunogen MAP3K7 antibody was raised against synthetic peptide based on mouse TAK1 (residues 563-579) with a cysteine C residue added and the peptide coupled to KLH
Plasmids, Primers & others

Target Details MAP3K7

Product Details anti-MAP3K7 Antibody Application Details Handling Images back to top
Antigen
Alternative Name TAK1 / MAP3K7 (MAP3K7 Antibody Abstract)
Background MEKK7, known as TAK1 for transforming growth factor (TGF) beta-activated kinase-1, is a MLK (MAP3K) type protein kinase which is associated with several signaling pathways. The protein contains a N-terminal protein kinase domain preceeded by a short regulatory motif and followed by a C-terminal extension of unknown function. TAK1 is activated by TGF beta and tumor necrosis factor (TNF). Further, TAK1 binding proteins, TAB-1 and -2, bind to the N-terminal regulatory motif and couple TAK1 to additional upstream signals, including the human X chromosome-linked inhibitor of apoptosis. TAK1 regulates the JNK cascade by phosphorylating MKK4/MAP2K4 and p38 cascades by phosphorylating MEK3/MAP2K3 and MKK6/MAP2K6. TAK1 also has been implicated in interleukin-1 (IL-1) signaling to JNKs via direct activation by IL-1 or by forming a complex with TRAF6, TAB1 and TAB2. At least four protein isoforms, resulting from alternatively spliced transcript variants, have been identified - 491, 518, 579 and 606 amino acids.Synonyms: Mitogen-activated protein kinase kinase kinase 7, TAK-1, TAK1, TGF-beta-activated kinase 1, Transforming growth factor-beta-activated kinase 1
Gene ID 6885
NCBI Accession NP_003179
UniProt O43318
Pathways NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades

Application Details

Product Details anti-MAP3K7 Antibody Target Details MAP3K7 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-MAP3K7 Antibody Target Details MAP3K7 Application Details Images back to top
Concentration 1.0 mg/mL
Buffer PBS, pH 7.2 containing 50 % Glycerol and 0.09 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-MAP3K7 Antibody Target Details MAP3K7 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 563-579) antibody (ABIN615309) Placenta, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 563-579) antibody (ABIN615309) Prostate, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 563-579) antibody (ABIN615309) Tonsil, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)