anti-Rat (Rattus) NFKB1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended NFKB1 Antibody (supplied by: Log in to see )

Antigen
Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) Antibodies
  • EBP-1
  • KBF1
  • NF-kB1
  • NF-kappa-B
  • NF-kappaB
  • NFKB-p105
  • NFKB-p50
  • NFkappaB
  • p105
  • p50
  • NF-kB
  • NF-KB1
  • ebp-1
  • kbf1
  • nf-kappa-b
  • nf-kappaB
  • nfkb-p105
  • nfkb-p50
  • NF-kappaB1
  • p50/p105
  • BICDR-1
  • bicdr1
  • ccdc64
  • nuclear factor kappa B subunit 1
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 L homeolog
  • nuclear factor NF-kappa-B p105 subunit
  • nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
  • NFKB1
  • Nfkb1
  • nfkb1.L
  • CpipJ_CPIJ012236
  • nfkb1
Epitope
AA 63-113
53
49
44
43
36
33
31
16
15
15
14
13
11
7
7
5
5
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
571
208
170
24
21
18
16
6
5
4
3
2
1
1
1
Host
Rabbit
506
89
2
1
Clonality
Polyclonal
Conjugate
This NFKB1 antibody is un-conjugated
17
17
14
8
8
6
6
6
6
6
6
6
6
6
4
4
3
2
2
2
2
2
2
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
477
243
159
156
124
79
53
34
29
11
11
5
4
4
3
2
1
1
Options
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Catalog No. ABIN673194
$ 318.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.4843445 ABIN218359 IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
12.4843445 ABIN4339346 ICC IF IHC IHC (p) WB Rabbit pSer927 Log in to see Polyclonal 0
12.4843445 ABIN498629 IHC (p) WB Rabbit Log in to see Polyclonal 0
1 ABIN3043587 IHC (p) WB Rabbit IgG AA 1-360 Log in to see Polyclonal 5
1 ABIN319253 IF IHC (p) WB Rabbit pSer927 Log in to see Polyclonal 4
1 ABIN1103248 IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal 0
1 ABIN197122 IHC (p) Rabbit Ser337 Log in to see Polyclonal 4
1 ABIN4339347 ICC IF IHC IHC (p) WB Rabbit pSer337 Log in to see Polyclonal 0
1 ABIN2889032 IHC (p) ELISA WB Rabbit IgG AA 899-948 Log in to see Polyclonal 0
1 ABIN2889036 IHC (p) ELISA WB Rabbit IgG AA 304-353 Log in to see Polyclonal 0
1 ABIN2888484 IHC (p) ELISA WB Rabbit IgG pSer337 Log in to see Polyclonal 0
1 ABIN302994 IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN673203 IHC (p) WB HRP Rabbit IgG AA 63-113 Log in to see Polyclonal 0
1 ABIN1737333 IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN673196 IHC (p) WB Biotin Rabbit IgG AA 63-113 Log in to see Polyclonal 0
1 ABIN1822735 IHC (p) WB Rabbit IgG pSer932 Log in to see Polyclonal 0
1 ABIN1822732 IHC (p) WB Rabbit IgG pSer337 Log in to see Polyclonal 0
1 ABIN2626048 IHC (p) WB Rabbit IgG AA 1-360 Log in to see Polyclonal 0
1 ABIN318079 EIA IHC (p) WB Rabbit pSer337 Log in to see Polyclonal 0
1 ABIN744272 IHC (p) WB HRP Rabbit IgG pSer927 Log in to see Polyclonal 0

General

Antigen Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) Antibodies
Epitope AA 63-113
(53), (49), (44), (43), (36), (33), (31), (16), (15), (15), (14), (13), (11), (7), (7), (5), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(571), (208), (170), (24), (21), (18), (16), (6), (5), (4), (3), (2), (1), (1), (1)
Host Rabbit
(506), (89), (2), (1)
Clonality
Polyclonal
Conjugate This NFKB1 antibody is un-conjugated
(17), (17), (14), (8), (8), (6), (6), (6), (6), (6), (6), (6), (6), (6), (4), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(477), (243), (159), (156), (124), (79), (53), (34), (29), (11), (11), (5), (4), (4), (3), (2), (1), (1)
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Product Details anti-NFKB1 Antibody

Target Details NFKB1 Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human NFKB1
Isotype IgG

Target Details NFKB1

Product Details anti-NFKB1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Nfkb P105 / P50 (NFKB1 Antibody Abstract)
Background

NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. NF-kappa-B heterodimeric p65-p50 and RelB-p50 complexes are transcriptional activators. The NF-kappa-B p50-p50 homodimer is a transcriptional repressor, but can act as a transcriptional activator when associated with BCL3. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing. The proteasome-mediated process ensures the production of both p50 and p105 and preserves their independent function, although processing of NFKB1/p105 also appears to occur post-translationally.

Subcellular location: Cytoplasm, Nucleus

Synonyms: p50, KBF1, p105, EBP-1, NF-kB1, NFKB-p50, NFkappaB, NF-kappaB, NFKB-p105, NF-kappa-B, Nuclear factor NF-kappa-B p105 subunit, DNA-binding factor KBF1, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, NFKB1

Gene ID 4790
UniProt P19838
Pathways p53 Signaling, NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Toll-Like Receptors Cascades

Application Details

Product Details anti-NFKB1 Antibody Target Details NFKB1 Handling Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-NFKB1 Antibody Target Details NFKB1 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-NFKB1 Antibody Target Details NFKB1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) (AA 63-113) antibody (ABIN673194) Formalin-fixed and paraffin embedded nasal polyps labeled with Anti-NF-ºBp50 Polyclo...
Western Blotting (WB) image for anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) (AA 63-113) antibody (ABIN673194) Mouse lung lysates probed with Rabbit Anti-NFkB p105/p50 Polyclonal Antibody, Unconju...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) (AA 63-113) antibody (ABIN673194) Formalin-fixed and paraffin embedded human gastric tissue labeled with Rabbit Anti-NF...
Western Blotting (WB) image for anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) (AA 63-113) antibody (ABIN673194) Mouse lung lysates probed with Rabbit Anti-NFkB p105/p50 Polyclonal Antibody, Unconju...