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|Antigen||Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, beta (NFKBIB) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This NFKBIB antibody is conjugated to Cy5 Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
|Supplier||Log in to see|
Product Details anti-NFKBIB AntibodyTarget Details NFKBIB Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic phosphopeptide derived from human NFKBIB around the phosphorylation site of Ser23|
Target Details NFKBIBProduct Details anti-NFKBIB Antibody Application Details Handling Images back to top
|Alternative Name||Ikb beta (NFKBIB Antibody Abstract)|
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011].
Synonyms: IKB beta Ser23, IKB beta S23, p-IKB beta Ser23, p-IKB beta S23, NFKBIBSer23, NFKBIBphospho S23, IkB-betaSer22, IkB beta, NF-kappa-B inhibitor beta, IKB beta, NF-kappa-BIB, TRIP-9, I-kappa-B-beta, IkappaBbeta, IkB-beta, IkB-B, Thyroid receptor-interacting protein 9, TR-interacting protein 9, NFKBIB, IKBB.
|Research Area||Immunology, Innate Immunity|
|Pathways||NF-kappaB Signaling, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades|
Application DetailsProduct Details anti-NFKBIB Antibody Target Details NFKBIB Handling Images back to top
|Application Notes||IF(IHC-P) 1:50-200|
|Restrictions||For Research Use only|
HandlingProduct Details anti-NFKBIB Antibody Target Details NFKBIB Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at 4°C|
|Expiry Date||12 months|