anti-Human NGFR antibody for ELISA

Recommended NGFR Antibody (supplied by: Log in to see )

Antigen
Nerve Growth Factor Receptor (NGFR) Antibodies
  • ngfr
  • wu:fb38c02
  • wu:fc10h01
  • CD271
  • Gp80-LNGFR
  • TNFRSF16
  • p75(NTR)
  • p75NTR
  • LNGFR
  • RNNGFRR
  • Tnfrsf16
  • p75
  • NRH1b
  • fullback
  • nrh1
  • p75ntr
  • tnfrsf16
  • p75NGFR
  • nerve growth factor receptor
  • neurotrophin receptor associated death domain
  • nerve growth factor receptor S homeolog
  • nerve growth factor receptor (TNFR superfamily, member 16)
  • NGFR
  • nradd
  • Ngfr
  • ngfr.S
Reactivity
Human
364
121
110
59
54
52
50
48
30
12
10
8
5
5
2
2
2
2
2
1
Host
Mouse
196
158
34
4
1
Clonality
Monoclonal
Conjugate
This NGFR antibody is un-conjugated
22
17
17
16
9
7
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Western Blotting (WB)
222
179
138
123
102
65
63
42
31
14
13
13
9
6
6
4
3
3
1
1
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Catalog No. ABIN2869468
$ 475.29
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN185411 ELISA WB Goat Internal Region Log in to see Polyclonal 1
1 ABIN969315 ICC FACS ELISA WB Mouse IgG1 Log in to see 2F1C2 4
1 ABIN297345 ELISA WB Goat AA 342-353 Log in to see Polyclonal 0
1 ABIN1103253 ELISA WB Goat AA 202-215 Log in to see Polyclonal 0
1 ABIN3185897 ELISA IF WB Rabbit IgG Internal Region Log in to see Polyclonal 0
1 ABIN3185896 ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal 0
1 ABIN1844512 ELISA FACS IF/ICC WB Mouse IgG1 Log in to see 0
1 ABIN467110 ELISA FACS Mouse IgG1 Log in to see 2F1C2 0
1 ABIN790852 ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2889383 IF ELISA WB Rabbit IgG AA 121-170 Log in to see Polyclonal 0
1 ABIN2659203 ELISA WB PE-Cy7 Mouse IgG1 kappa Log in to see ME20-4 7
1 ABIN6266352 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN6263633 ELISA ICC IF WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2465256 ELISA WB Goat Internal Region Log in to see Polyclonal 0
1 ABIN1453653 ELISA WB Rabbit IgG AA 230-279 Log in to see Polyclonal 0
1 ABIN5584499 ELISA WB Goat Log in to see Polyclonal 0
1 ABIN6260601 ELISA ICC IF WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN4902013 ELISA FACS IF WB Mouse IgG1 Log in to see 2F1C2 0
1 ABIN3031958 IHC ELISA WB Rabbit Ig Fraction AA 353-380 Log in to see Polyclonal 0
1 ABIN2884668 ELISA WB Rabbit IgG AA 230-279 Log in to see Polyclonal 0

General

Antigen Nerve Growth Factor Receptor (NGFR) Antibodies
Reactivity Human
(364), (121), (110), (59), (54), (52), (50), (48), (30), (12), (10), (8), (5), (5), (2), (2), (2), (2), (2), (1)
Host Mouse
(196), (158), (34), (4), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This NGFR antibody is un-conjugated
(22), (17), (17), (16), (9), (7), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Western Blotting (WB)
(222), (179), (138), (123), (102), (65), (63), (42), (31), (14), (13), (13), (9), (6), (6), (4), (3), (3), (1), (1)
Pubmed 4 references available
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Product Details anti-NGFR Antibody

Target Details NGFR Application Details Handling References for anti-NGFR antibody (ABIN2869468) Images
Purpose Purified Mouse Monoclonal Antibody
Characteristics Synonyms: Tumor necrosis factor receptor superfamily member 16, Gp80-LNGFR, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, NGF receptor, p75 ICD, CD271, NGFR, TNFRSF16
Purification Ascitic fluid
Immunogen

Immunogen: Purified recombinant fragment of human NGFR expressed in E. Coli.

Antigen Type: Recombinant Protein

Clone 2F1C2
Isotype IgG1
Plasmids, Primers & others

Target Details NGFR

Product Details anti-NGFR Antibody Application Details Handling References for anti-NGFR antibody (ABIN2869468) Images back to top
Antigen
Alternative Name NGFR (NGFR Antibody Abstract)
Background

Other Names: Tumor necrosis factor receptor superfamily member 16, Gp80-LNGFR, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, NGF receptor, p75 ICD, CD271, NGFR, TNFRSF16

Description: Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGFR p75 plays a central role in the regulation of cell number by apoptosis in the developing CNS. During early development, activation of NGFR p75 by NGF induces apoptotic cell death in some neuronal cells, probably through activation of the sphingomyelinase/ceramide pathway, the ICE like proteases and the JNK pathway. In rat Schwann cells, NGF binding to NGFR p75 activates NF kappaB, possibly to modulate Schwann cell migration during nerve regeneration. CD271 has recently been described as being expressed in mesenchymal stem cells (bone marrow stromal cells).

Molecular Weight 45183
Gene ID 4804
UniProt P08138
Pathways NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding

Application Details

Product Details anti-NGFR Antibody Target Details NGFR Handling References for anti-NGFR antibody (ABIN2869468) Images back to top
Application Notes Western Bloting: = 1:500 - 2000. Immunofluorescence: = 1:200 - 1000. Flow cytometry: = 1:200 - 400.
Restrictions For Research Use only

Handling

Product Details anti-NGFR Antibody Target Details NGFR Application Details References for anti-NGFR antibody (ABIN2869468) Images back to top
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References for anti-NGFR antibody (ABIN2869468)

Product Details anti-NGFR Antibody Target Details NGFR Application Details Handling Images back to top
Background publications

He, Garcia: "Structure of nerve growth factor complexed with the shared neurotrophin receptor p75." in: Science (New York, N.Y.), Vol. 304, Issue 5672, pp. 870-5, 2004

Hu, Zhang, Qin, Xu, Swaab, Zhou: "Increased p75(NTR) expression in hippocampal neurons containing hyperphosphorylated tau in Alzheimer patients." in: Experimental neurology, Vol. 178, Issue 1, pp. 104-11, 2002

DiDonato, Hayakawa, Rothwarf, Zandi, Karin: "A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB." in: Nature, Vol. 388, Issue 6642, pp. 548-54, 1997

Fantini, Johansson: "Expression of growth-associated protein 43 and nerve growth factor receptor in human skin: a comparative immunohistochemical investigation." in: The Journal of investigative dermatology, Vol. 99, Issue 6, pp. 734-42, 1993

Images

Product Details anti-NGFR Antibody Target Details NGFR Application Details Handling References for anti-NGFR antibody (ABIN2869468) back to top
Supplier Images
Western Blotting (WB) image for anti-Nerve Growth Factor Receptor (NGFR) antibody (ABIN2869468) Figure 1: Western blot analysis using NGFR mouse mAb against NGFR-hIgGFc transfected ...
Immunofluorescence (IF) image for anti-Nerve Growth Factor Receptor (NGFR) antibody (ABIN2869468) Figure 2:Immunofluorescence analysis of EC cells using NGFR mouse mAb (green). Red: A...
Flow Cytometry (FACS) image for anti-Nerve Growth Factor Receptor (NGFR) antibody (ABIN2869468) Figure 3: Flow cytometric analysis of EC cells using NGFR mouse mAb (green) and negat...
Immunohistochemistry (IHC) image for anti-Nerve Growth Factor Receptor (NGFR) antibody (ABIN2869468) Figure 2: Immunohistochemical analysis of paraffin-embedded human lung cancer (left) ...