anti-Human TNFRSF1A antibody for Immunohistochemistry (Formalin-fixed Sections)

Recommended TNFRSF1A Antibody

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Antibodies
  • CD120a
  • FPF
  • MS5
  • TBP1
  • TNF-R
  • TNF-R-I
  • TNF-R55
  • TNFAR
  • TNFR1
  • TNFR1-d2
  • TNFR55
  • TNFR60
  • p55
  • p55-R
  • p60
  • TNF-R1
  • TNF-alphaR1
  • TNFRI
  • TNFRp55
  • TNFalpha-R1
  • Tnfr-2
  • Tnfr1
  • fpf
  • tbp1
  • p55-r
  • tnf-r
  • tnfar
  • tnfr1
  • cd120a
  • tnfr55
  • tnfr60
  • xtnfr1
  • wu:fj65b10
  • zgc:85914
  • TNFR I
  • TNFRSF1A
  • TNFA
  • cTNF
  • TNF receptor superfamily member 1A
  • tumor necrosis factor receptor superfamily, member 1a
  • TNF receptor superfamily member 1A S homeolog
  • tumor necrosis factor
  • TNFRSF1A
  • Tnfrsf1a
  • tnfrsf1a.S
  • tnfrsf1a
  • TNF
Reactivity
Human
366
202
152
81
76
72
67
12
10
6
6
5
5
3
2
2
1
Host
Mouse
304
84
20
15
6
2
1
Clonality
Monoclonal
Conjugate
This TNFRSF1A antibody is un-conjugated
34
27
24
12
10
10
5
5
4
4
4
4
4
3
3
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
295
178
133
131
117
58
46
36
34
27
23
19
13
12
9
5
2
2
2
2
1
1
1
1
1
Options
Catalog No. ABIN1981872
$ 343.07
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
18.049534 ABIN2749013 Func IHC (f) FACS IP IHC (p) Mouse IgG2a H398 2
13.549533 ABIN5711607 FACS Func IHC (f) IHC (p) IP PE Mouse IgG2a H398 0

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Antibodies
Reactivity Human
(366), (202), (152), (81), (76), (72), (67), (12), (10), (6), (6), (5), (5), (3), (2), (2), (1)
Host Mouse
(304), (84), (20), (15), (6), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF1A antibody is un-conjugated
(34), (27), (24), (12), (10), (10), (5), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(295), (178), (133), (131), (117), (58), (46), (36), (34), (27), (23), (19), (13), (12), (9), (5), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 1 reference available
Supplier

Product Details anti-TNFRSF1A Antibody

Target Details TNFRSF1A Application Details Handling References for anti-TNFRSF1A antibody (ABIN1981872) Images
Specificity The mouse monoclonal antibody H398 recognizes the extracellular domain of CD120a, a 55 kDa receptor for tumor necrosis factor. The antibody blocks biological activity of both natural and recombinant human TNF alpha and TNF beta.
Cross-Reactivity (Details) Human
Purification Purified by protein-A affinity chromatography
Purity > 95 % (by SDS-PAGE)
Immunogen Recombinant full length human CD120a
Clone H398
Isotype IgG2a
Plasmids, Primers & others

Target Details TNFRSF1A

Product Details anti-TNFRSF1A Antibody Application Details Handling References for anti-TNFRSF1A antibody (ABIN1981872) Images back to top
Antigen
Alternative Name CD120a (TNFRSF1A Antibody Abstract)
Background CD120a / TNF R1, also known as TNFR55 or TNFRSF1A, is a 55 kDa receptor for tumor necrosis factor alpha and it is expressed in most tissues. By binding its trimeric ligand the CD120a protein forms trimers and the conformation change leads to dissociation of the inhibitory factor SODD from its intracellular death domain and in formation of signaling platform. CD120a can mediate apoptosis, and function as a regulator of inflammation. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease.
Gene ID 7132
Pathways NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Hepatitis C

Application Details

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Handling References for anti-TNFRSF1A antibody (ABIN1981872) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Application Details References for anti-TNFRSF1A antibody (ABIN1981872) Images back to top
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze. Do not use after expiration date stamped on vial label.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.

References for anti-TNFRSF1A antibody (ABIN1981872)

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Application Details Handling Images back to top
Product cited in:

Baker, Pettitt, Slupsky, Chen, Glenn, Zuzel, Cawley: "Response of hairy cells to IFN-alpha involves induction of apoptosis through autocrine TNF-alpha and protection by adhesion." in: Blood, Vol. 100, Issue 2, pp. 647-53, 2002