anti-Rat (Rattus) TNFRSF1A antibody for Flow Cytometry

Recommended TNFRSF1A Antibody

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Antibodies
  • CD120a
  • FPF
  • MS5
  • TBP1
  • TNF-R
  • TNF-R-I
  • TNF-R55
  • TNFAR
  • TNFR1
  • TNFR1-d2
  • TNFR55
  • TNFR60
  • p55
  • p55-R
  • p60
  • TNF-R1
  • TNF-alphaR1
  • TNFRI
  • TNFRp55
  • TNFalpha-R1
  • Tnfr-2
  • Tnfr1
  • fpf
  • tbp1
  • p55-r
  • tnf-r
  • tnfar
  • tnfr1
  • cd120a
  • tnfr55
  • tnfr60
  • xtnfr1
  • wu:fj65b10
  • zgc:85914
  • TNFR I
  • TNFRSF1A
  • TNFA
  • cTNF
  • TNF receptor superfamily member 1A
  • tumor necrosis factor receptor superfamily, member 1a
  • TNF receptor superfamily member 1A S homeolog
  • tumor necrosis factor
  • TNFRSF1A
  • Tnfrsf1a
  • tnfrsf1a.S
  • tnfrsf1a
  • TNF
Reactivity
Human, Rat (Rattus)
338
188
143
75
70
67
62
13
10
6
6
5
5
3
2
1
1
1
Host
Mouse
281
80
15
15
6
2
1
Clonality
Monoclonal
Conjugate
This TNFRSF1A antibody is conjugated to Biotin
30
26
24
12
10
10
5
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Western Blotting (WB)
277
164
120
118
105
58
41
31
28
27
22
19
13
8
7
5
3
2
2
1
1
1
1
Options
Catalog No. ABIN1105795
$ 379.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
5.5 ABIN1105792 Func EIA IHC (fro) FACS IP WB Mouse IgG2a H398 5
1 ABIN6719287 FACS ICC IHC (fro) IHC (p) WB Rabbit IgG AA 22-211 Polyclonal 0
-13.157533 ABIN4360834 FACS IHC IHC (p) IP WB Rabbit Polyclonal 0

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Antibodies
Reactivity Human, Rat (Rattus)
(338), (188), (143), (75), (70), (67), (62), (13), (10), (6), (6), (5), (5), (3), (2), (1), (1), (1)
Host Mouse
(281), (80), (15), (15), (6), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF1A antibody is conjugated to Biotin
(30), (26), (24), (12), (10), (10), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Western Blotting (WB)
(277), (164), (120), (118), (105), (58), (41), (31), (28), (27), (22), (19), (13), (8), (7), (5), (3), (2), (2), (1), (1), (1), (1)
Pubmed 5 references available
Supplier

Product Details anti-TNFRSF1A Antibody

Target Details TNFRSF1A Application Details Handling References for anti-TNFRSF1A antibody (ABIN1105795) Images
Cross-Reactivity (Details) Species reactivity (tested):Human, rat
Purification Protein G
Clone H398
Isotype IgG2a
Plasmids, Primers & others

Target Details TNFRSF1A

Product Details anti-TNFRSF1A Antibody Application Details Handling References for anti-TNFRSF1A antibody (ABIN1105795) Images back to top
Antigen
Alternative Name CD120a / TNFR1 (TNFRSF1A Antibody Abstract)
Background TNF-RI (~55-60 kDa) is present on most cell types and is considered to play a prominent role in cell stimulation by TNF-alpha. TNF-alpha activates inflammatory responses, induces apoptosis, regulates cellular proliferation, and may even promote cancer progression. The effects of TNF-alpha are mediated by TNF-RI and TNF-RII, which have both distinct and overlapping downstream signaling cascades. Induction of cytotoxicity and other functions are mediated largely via TNF-RI. TNF-RI is equally well activated by both the 17 kDa soluble and 26 kDa membrane-bound form, whereas TNF-RII is efficiently activated only by the membrane bound form of TNF-alpha. TNF-RI signaling is initiated when trimeric TNF-alpha binds TNF-RI receptors. Subsequent TNF-RI trimerization promotes the recruitment of a proximal signaling complex composed of TNF Receptor Associated protein with a Death Domain (TRADD), Receptor Interacting Protein (RIP), cellular Inhibitor of Apoptosis Protein 1 (cIAP1), TNF Receptor Associated Factor 2 (TRAF2), and likely TRAF5. Studies with TNF-RI-deficient mice indicate that TNF-RI mediates most of the proliferation, pro-inflammatory, and apoptosis-activating pathways.Synonyms: TNF-R1, TNF-RI, TNFR-I, Tnfrsf1a, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor type I, p55, p60
Gene ID 9606
UniProt P19438
Pathways NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Hepatitis C

Application Details

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Handling References for anti-TNFRSF1A antibody (ABIN1105795) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Application Details References for anti-TNFRSF1A antibody (ABIN1105795) Images back to top
Concentration 0.1 mg/mL
Buffer PBS, 0.02 % sodium azide, 1 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
Expiry Date 6 months

References for anti-TNFRSF1A antibody (ABIN1105795)

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Application Details Handling Images back to top
Background publications

Leccardi, Decarli, Lorenzelli, Milani, Mettala, Orava, Barborini: "Long-term outdoor reliability assessment of a wireless unit for air-quality monitoring based on nanostructured films integrated on micromachined platforms." in: Sensors (Basel, Switzerland), Vol. 12, Issue 6, pp. 8176-92, 2012

Kontermann, Münkel, Neumeyer, Müller, Branschädel, Scheurich, Pfizenmaier: "A humanized tumor necrosis factor receptor 1 (TNFR1)-specific antagonistic antibody for selective inhibition of tumor necrosis factor (TNF) action." in: Journal of immunotherapy (Hagerstown, Md. : 1997), Vol. 31, Issue 3, pp. 225-34, 2008

Grell, Scheurich, Meager, Pfizenmaier: "TR60 and TR80 tumor necrosis factor (TNF)-receptors can independently mediate cytolysis." in: Lymphokine and cytokine research, Vol. 12, Issue 3, pp. 143-8, 1993

Thoma, Grell, Pfizenmaier, Scheurich: "Identification of a 60-kD tumor necrosis factor (TNF) receptor as the major signal transducing component in TNF responses." in: The Journal of experimental medicine, Vol. 172, Issue 4, pp. 1019-23, 1990

Product cited in:

Krippner-Heidenreich, Grunwald, Zimmermann, Kühnle, Gerspach, Sterns, Shnyder, Gill, Männel, Pfizenmaier, Scheurich: "Single-chain TNF, a TNF derivative with enhanced stability and antitumoral activity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 12, pp. 8176-83, 2008