Browse our anti-TNFRSF1B (TNFRSF1B) Antibodies

Human Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) interaction partners

1. TL1A (show TNFSF15 Antibodies) modulated Rheumatoid arthritis-fibroblast-like synoviocytes migration and Indian hedgehog (show IHH Antibodies) signaling pathway using TNFR2.

2. Genotype rs767455 was associated with the susceptibility of ankylosing spondylitis(AS), G allele of rs767455 exhibited an association with the risk of developing AS. Only rs1061622 was significantly associated with long-term efficacy of etanercept. The results suggest that TNFRSF1A (show TNFRSF1A Antibodies) and TNFRSF1B polymorphisms were associated with susceptibility, severity, and the long-term therapeutic efficacy of etanercept of AS patients.

3. Data suggest that maternal glycemic response during pregnancy is associated with lower DNA methylation (show HELLS Antibodies) of 4 CpG sites within PDE4B (show PDE4B Antibodies) gene in placenta (collected after normal-weight term birth); 3 additional CpG sites are differentially methylated relative to maternal glucose response within TNFRSF1B, LDLR (show LDLR Antibodies), and BLM (show BLM Antibodies) genes. (PDE4B (show PDE4B Antibodies) = phosphodiesterase-4B; LDLR (show LDLR Antibodies) = low density lipoprotein receptor (show LDLR Antibodies); BLM (show BLM Antibodies) = Bloom syndrome protein (show BLM Antibodies))

4. serum level did not change after tonsillectomy alone but decreased significantly after steroid pulse therapy in patients with IgA (show IgA Antibodies) nephropathy

5. Elevated serum TNFR2 may be a possible marker of COPD (show ARCN1 Antibodies) in asymptomatic smokers and ex-smokers.

6. TNFR2 promoted Adriamycin resistance in breast cancer cells by regulating the DNA damage repair.

7. Serum TNFR2 is a biomarker for patients with chronic kidney disease.

8. Data indicate activators of tumor necrosis factor receptor 2 (TNFR2) and a potential role for this target in immunotherapy.

9. In this study, we identified a novel association between ANCA levels, TNFRSF1B genotype and decreased circulating TNFR2 levels, which may be reflective of the underlying biological mechanisms that determine clinical expression and/or response to certain therapies.

10. In Han Chinese population of Hunan province, TNFRSF1B+676 gene polymorphisms are not associated with the genetic risk of rheumatoid arthritis

Cow (Bovine) Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) interaction partners

1. These results show an unclear effect of considered T>C polymorphism on TNF-RII gene expression in bovine leukocytes and they suggest the involvement of BLV in modifying the TNF-RII expression in BLV-infected cows.

2. These results suggest that the endometrium might lower the TNF (show TNF Antibodies) concentration in the blastocyst by (1) regulating TNF (show TNF Antibodies) secretion into the uterine fluid and (2) inducing decreased TNF (show TNF Antibodies) and TNFR2 mRNA transcription in the embryo.

3. These results suggest that TNF-alpha (show TNF Antibodies) sources include immune cells, as well as large and small luteal cells, and that TNF-RI (show TNFRSF1A Antibodies) and TNF-RII are present in the luteal cells of the bovine corpus luteum.

4. The expression and cellular localization of tumor necrosis factor-alpha (TNF (show TNF Antibodies)) and its receptors (TNFRI (show TNFRSF1A Antibodies) and TNFRII) mRNAs and proteins, were determined.[TNFRII]

Pig (Porcine) Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) interaction partners

1. Retinal ischemia results in increased expression of TNF-alpha (show TNF Antibodies) and its receptors (TNF-R1 (show TNFRSF1A Antibodies) and TNF-R2).

2. Porcine TNFR2 (1,125 bp, 375 amino acid residues), which contains specific amino acid region of transmembrane, indicated high identities with human and murine TNFR2

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) interaction partners

1. TNFR2 sensitizes macrophages for endogenous TNF (show TNF Antibodies)-induced TNFR1 (show TNFRSF1A Antibodies)-mediated necroptosis

2. study reports an important role for TNFR2 on low-affinity-primed secondary effector CD8 (show CD8A Antibodies)+ T cells; results demonstrate the importance of TNF (show TNF Antibodies) signaling in low-affinity, cross-reactive CD8 (show CD8A Antibodies)+ T cell responses during heterologous immunity

3. TNF (show TNF Antibodies) plays an inhibitory role in modulating myocardial SDF-1 (show CXCL12 Antibodies) production and blockade of TNF (show TNF Antibodies) signaling by ablation of TNFR1 (show TNFRSF1A Antibodies) and TNFR2 genes increased SDF-1 (show CXCL12 Antibodies) expression in the heart. These data expand on TNF (show TNF Antibodies) signaling-initiated mechanisms in myocardium, which may lend a more complete understanding of SDF-1 (show CXCL12 Antibodies) and TNFR (show TNFRSF1A Antibodies)-derived actions in hopes of advancing ischemic heart injury treatments.

4. Results suggest that elevated TNF (show TNF Antibodies) in the heart, via TNFR1 (show TNFRSF1A Antibodies) and TNFR2, restrains cardiomyocyte differentiation of resident cardiac stem cells and may enhance adrenergic activation, both effects that would reduce the effectiveness of endogenous cardiac repair and the response to exogenous stem cell therapy, while promoting adverse cardiac remodeling.

5. Report chronic inflammatory multiorgan hepatobiliary pancreatitis, along with fibrosis and calculi formation induced by oral dibutyltin administration in TNFR1 (show TNFRSF1A Antibodies)/R2 deficient mice.

6. These findings implicate TNF (show TNF Antibodies)-receptor signaling cascades in the regulation of homeostatic plasticity of denervated networks and suggest an important role for TNFalpha (show TNF Antibodies)-signaling in the course of neurological diseases accompanied by deafferentation.

7. TNF (show TNF Antibodies) receptor 1 (TnfR1 (show TNFRSF1A Antibodies)) signaling is believed to be a major mediator of the cytotoxicity of Tnf-a (show TNF Antibodies) through activation of caspases.

8. our findings implicate TNFR2 in supporting myeloid-derived suppressor cells -mediated immune suppression and metastasis in the liver

9. TNFR2 blockade appears to disrupt commensal bacteria-host immune symbiosis to reveal autoimmune demyelination in genetically susceptible mice.

10. TNFR2 protects mice from colitis by inhibiting the expansion of colonic CD8 (show CD8A Antibodies)(+) T cells.

Zebrafish Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) interaction partners

1. Targeted gene knockdown of TNFRSF1B in zebrafish embryos results in the induction of a caspase-8 (show CASP8 Antibodies), caspase-2 (show CASP2 Antibodies) and P53 (show TP53 Antibodies)-dependent apoptotic program in endothelial cells that bypasses caspase-3 (show CASP3 Antibodies).