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|Antigen||Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) Antibodies|
|Epitope||Extracellular Domain Alternatives|
|Conjugate||This TNFRSF1B antibody is un-conjugated Alternatives|
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS)
|7 references available|
Product Details anti-TNFRSF1B AntibodyTarget Details TNFRSF1B Application Details Handling References for anti-TNFRSF1B antibody (ABIN4900548) Images
|Specificity||Detects human TNF RII in direct ELISAs and Western blots. In direct ELISAs, this antibody does not cross-react with recombinant human (rh) 4-1BB, rhBAFF R, rhCD27, rhCD30, rhCD40, rhDR3, rhDR6, rhEDAR, rhFas, rhGITR, rhHVEM, rhLymophotactin beta R, rhNGF R, rhOPG, recombinant mouse (rm) OX40, rhRANK, rhTAJ, rhTNF RI, or rmTNF RII.|
|Purification||Protein A or G purified from hybridoma culture supernatant|
|Sterility||0.2 μm filtered|
|Immunogen||E. coli-derived recombinant human TNF RII, Extracellular domain|
|Plasmids, Primers & others|
Target Details TNFRSF1BProduct Details anti-TNFRSF1B Antibody Application Details Handling References for anti-TNFRSF1B antibody (ABIN4900548) Images back to top
|Alternative Name||TNF RII/TNFRSF1B (TNFRSF1B Antibody Abstract)|
|Background||Alternative Names: CD120b, CD120b antigen, Etanercept, p75 TNF receptor, p75TBPII, p75TNFR, soluble TNFR1B variant 1, TNFBRp80 TNF-alpha receptor, TNF-R2, TNFR2TNFR1B, TNF-R75, TNFR80, TNFRII, TNF-RII, TNF-R-II, TNFR-II, TNFRSF1B, tumor necrosis factor beta receptor, tumor necrosis factor binding protein 2, Tumor necrosis factor receptor 2, tumor necrosis factor receptor superfamily member 1B, tumor necrosis factor receptor superfamily, member 1B, Tumor necrosis factor receptor type II|
|Pathways||NF-kappaB Signaling, Apoptosis, Cellular Response to Molecule of Bacterial Origin, Hepatitis C|
Application DetailsProduct Details anti-TNFRSF1B Antibody Target Details TNFRSF1B Handling References for anti-TNFRSF1B antibody (ABIN4900548) Images back to top
Flow Cytometry 2.5 μg/10^6 cells
|Restrictions||For Research Use only|
HandlingProduct Details anti-TNFRSF1B Antibody Target Details TNFRSF1B Application Details References for anti-TNFRSF1B antibody (ABIN4900548) Images back to top
|Reconstitution||Reconstitute at 0.5 mg/mL in sterile PBS.|
|Buffer||Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.|
|Storage||4 °C,-20 °C,-80 °C|
|Storage Comment||Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.|
|Expiry Date||12 months|
References for anti-TNFRSF1B antibody (ABIN4900548)Product Details anti-TNFRSF1B Antibody Target Details TNFRSF1B Application Details Handling Images back to top
|Product cited in:||
Mizrahi, Ash, Peled, Yaniv, Stein, Askenasy: "Negative selection by apoptosis enriches progenitors in naïve and expanded human umbilical cord blood grafts." in: Bone marrow transplantation, Vol. 49, Issue 7, pp. 942-9, 2014 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).
Renaud, Sullivan, Graham: "Tumour necrosis factor alpha stimulates the production of monocyte chemoattractants by extravillous trophoblast cells via differential activation of MAPK pathways." in: Placenta, Vol. 30, Issue 4, pp. 313-9, 2009 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).
Maneechotesuwan, Wamanuttajinda, Kasetsinsombat, Huabprasert, Yaikwawong, Barnes, Wongkajornsilp: "Der p 1 suppresses indoleamine 2, 3-dioxygenase in dendritic cells from house dust mite-sensitive patients with asthma." in: The Journal of allergy and clinical immunology, Vol. 123, Issue 1, pp. 239-48, 2009 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).
Seal, Hockenbery, Spaulding, Kiem, Abbassi, Deeg: "Differential responses of FLIPLong and FLIPShort-overexpressing human myeloid leukemia cells to TNF-alpha and TRAIL-initiated apoptotic signals." in: Experimental hematology, Vol. 36, Issue 12, pp. 1660-72, 2008 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).
Georgopoulos, Steele, Thomson, Selby, Southgate, Trejdosiewicz: "A novel mechanism of CD40-induced apoptosis of carcinoma cells involving TRAF3 and JNK/AP-1 activation." in: Cell death and differentiation, Vol. 13, Issue 10, pp. 1789-801, 2006 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).
Ebert, Mehta: "Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription." in: Cellular immunology, Vol. 241, Issue 1, pp. 7-13, 2006 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).
Birebent, Lorho, Lechartier, de Guibert, Alizadeh, Vu, Beauplet, Robillard, Semana: "Suppressive properties of human CD4+CD25+ regulatory T cells are dependent on CTLA-4 expression." in: European journal of immunology, Vol. 34, Issue 12, pp. 3485-96, 2004 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).