anti-Human TRAF2 antibody for Immunofluorescence

Recommended TRAF2 Antibody (supplied by: Log in to see )

Antigen
TNF Receptor-Associated Factor 2 (TRAF2) Antibodies
  • MGC:45012
  • TRAP
  • TRAP3
  • TANK
  • AI325259
  • TNF-receptor-associated factor 2
  • conjugal transfer protein TraF
  • TNF receptor associated factor 2
  • TNF receptor-associated factor 2
  • Tnf receptor-associated factor 2
  • LOC661716
  • traF2
  • TRAF2
  • Traf2
Reactivity
Human
203
71
59
6
3
3
2
2
1
1
Host
Mouse
123
65
21
1
Clonality
Monoclonal
Conjugate
This TRAF2 antibody is un-conjugated
8
8
7
5
5
4
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
187
104
83
60
31
29
19
13
10
6
6
4
3
3
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Catalog No. ABIN659110
$ 335.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.155504 ABIN1875191 ICC IF IHC IP WB Rabbit IgG Log in to see Polyclonal 0
12.155504 ABIN4361656 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
12.155504 ABIN3198353 IC IF IHC IP WB Rabbit Log in to see Polyclonal 0
12.155504 ABIN4361655 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
12.155504 ABIN3029148 IF ELISA WB Mouse IgG1, kappa Log in to see 214CT16-3-4 0
1 ABIN252172 ICC FACS IF IHC (p) IP IHC WB Rabbit Log in to see Polyclonal 3
1 ABIN1104799 IF ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal 0
1 ABIN2888039 ICC IF IHC IP WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN4361657 ICC IF IP WB Mouse IgG1 kappa Log in to see 214CT16-3-4 0
1 ABIN5682577 ELISA FACS ICC IF IHC WB Mouse IgG1 AA 39-188 Log in to see 5C2C3 0
1 ABIN1943765 IF IHC IHC (p) IP Rabbit IgG AA 300-350 Log in to see Polyclonal 0
1 ABIN2379079 IF ELISA WB Mouse IgG1 kappa Log in to see 214CT16-3-4 0
1 ABIN1808721 IF WB Mouse IgG1, kappa Log in to see 0
1 ABIN2379073 IF ELISA WB APC Mouse IgG1 kappa Log in to see 214CT16-3-4 0
1 ABIN2379075 IF ELISA WB FITC Mouse IgG1 kappa Log in to see 214CT16-3-4 0
1 ABIN5965367 IF WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2702189 IC IF IP IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN4914798 IF WB Mouse IgG1 kappa Log in to see 214CT16-3-4 0
1 ABIN2379072 IF ELISA WB Alkaline Phosphatase (AP) Mouse IgG1 kappa Log in to see 214CT16-3-4 0
1 ABIN2379084 IF WB PE Mouse IgG1 kappa Log in to see 214CT16-3-4 0

General

Antigen TNF Receptor-Associated Factor 2 (TRAF2) Antibodies
Reactivity Human
(203), (71), (59), (6), (3), (3), (2), (2), (1), (1)
Host Mouse
(123), (65), (21), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TRAF2 antibody is un-conjugated
(8), (8), (7), (5), (5), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (IF), Western Blotting (WB)
(187), (104), (83), (60), (31), (29), (19), (13), (10), (6), (6), (4), (3), (3)
Pubmed 1 reference available
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Product Details anti-TRAF2 Antibody

Target Details TRAF2 Application Details Handling References for anti-TRAF2 antibody (ABIN659110) Images
Specificity This TRAF2 monoclonal antibody is generated from mouse immunized with TRAF2 recombinant protein.
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.
Immunogen This TRAF2 monoclonal antibody is generated from mouse immunized with TRAF2 recombinant protein.
Clone 214CT16-3-4
Isotype IgG1, kappa
Plasmids, Primers & others

Target Details TRAF2

Product Details anti-TRAF2 Antibody Application Details Handling References for anti-TRAF2 antibody (ABIN659110) Images back to top
Antigen
Alternative Name TRAF2 (TRAF2 Antibody Abstract)
Background The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined.
Synonyms: TNF receptor-associated factor 2,TRAF2,TRAP3
Pathways: Hepatitis C, Adipocytokine signaling pathway, MAPK signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Protein processing in endoplasmic reticulum, Small cell lung cancer, Apoptosis, Osteoclast differentiation
Molecular Weight 55859 Da
Gene ID 7186
UniProt Q12933
Pathways NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Unfolded protein response

Application Details

Product Details anti-TRAF2 Antibody Target Details TRAF2 Handling References for anti-TRAF2 antibody (ABIN659110) Images back to top
Application Notes IF = 1:10-50, WB = 1:100-1000
Restrictions For Research Use only

Handling

Product Details anti-TRAF2 Antibody Target Details TRAF2 Application Details References for anti-TRAF2 antibody (ABIN659110) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References for anti-TRAF2 antibody (ABIN659110)

Product Details anti-TRAF2 Antibody Target Details TRAF2 Application Details Handling Images back to top
Background publications

Alvarez, Harikumar, Hait, Allegood, Strub, Kim, Maceyka, Jiang, Luo, Kordula, Milstien, Spiegel: "Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2." in: Nature, Vol. 465, Issue 7301, pp. 1084-8, 2010

Images

Product Details anti-TRAF2 Antibody Target Details TRAF2 Application Details Handling References for anti-TRAF2 antibody (ABIN659110) back to top
Supplier Images
Immunofluorescence (IF) image for anti-TNF Receptor-Associated Factor 2 (TRAF2) antibody (ABIN659110) Confocal immunofluorescent analysis of TRAF2 Antibody with MCF-7 cell followed by Al...
Western Blotting (WB) image for anti-TNF Receptor-Associated Factor 2 (TRAF2) antibody (ABIN659110) TRAF2/MB10188 antibody western blot analysis in T47D cell line lysates (35ug/lane).T...
Western Blotting (WB) image for anti-TNF Receptor-Associated Factor 2 (TRAF2) antibody (ABIN659110) All lanes : Anti- at 1:1000 dilution Lane 1: 293 whole cell lysate Lane 2: Hela whole...