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|Antigen||Nuclear Receptor Co-Repressor 1 (NCOR1) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This NCOR1 antibody is conjugated to Alexa Fluor 647 Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
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Product Details anti-NCOR1 AntibodyTarget Details NCOR1 Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human NC0R1|
Target Details NCOR1Product Details anti-NCOR1 Antibody Application Details Handling Images back to top
|Alternative Name||NCoR1 (NCOR1 Antibody Abstract)|
Nuclear co-repressor 2 (N-CoR2) gene (NCOR2, previously called silencing mediator for retinoid and thyroid hormone receptor SMRT) is recruited to nuclear and non-nuclear receptors in a large repressing complex containing also N-CoR1, mSin3 and HDACs. This large complex represses transcription in absence of ligand. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Tissue specificity: Ubiquitous. It is belongs to the N-CoR nuclear receptor corepressors family.
Synonyms: RIP13, Rxrip13, hCIT529I10, hN CoR, hNCoR, KIAA1047, MGC104216, N CoR, N Cor/SMRT corepressor Rip13, N CoR1, NCOR 1, NCoR, NCOR1, Nuclear receptor co repressor 1, Nuclear receptor corepressor 1, Retinoid X receptor interacting protein 13, thyroid hormone and retinoic acid receptor associated corepressor 1, thyroid hormone- and retinoic acid receptor-associated corepressor 1, TRAC 1, TRAC1, Nuclear Receptor Corepressor NCoR, NCOR1_MOUSE.
|Pathways||Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process|
Application DetailsProduct Details anti-NCOR1 Antibody Target Details NCOR1 Handling Images back to top
|Application Notes||IF(IHC-P) 1:50-200|
|Restrictions||For Research Use only|
HandlingProduct Details anti-NCOR1 Antibody Target Details NCOR1 Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at 4°C|
|Expiry Date||12 months|