anti-Dog (Canine) Nuclear Receptor Subfamily 1, Group D, Member 2 antibody for Western Blotting

Recommended Nuclear Receptor Subfamily 1, Group D, Member 2 Antibody (supplied by: Log in to see )

Antigen
Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2) Antibodies
  • BD73
  • EAR-1R
  • RVR
  • HZF-2
  • Rev-erb
  • REV-ERBB
  • NR1D2
  • rvr
  • bd73
  • hzf2
  • ear-1r
  • hs.37288
  • NR1D2-A
  • Reverbbeta-A
  • reverbb1
  • nuclear receptor subfamily 1 group D member 2
  • nuclear receptor subfamily 1, group D, member 2
  • nuclear receptor subfamily 1, group D, member 2a
  • NR1D2
  • Nr1d2
  • nr1d2
  • nr1d2a
Epitope
N-Term
11
10
10
8
8
6
5
5
5
4
2
2
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
70
15
12
8
8
8
7
6
5
5
4
3
2
2
1
1
1
Host
Rabbit
61
12
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
2
2
2
Application
Western Blotting (WB)
48
29
28
21
3
2
2
1
1
1
Options
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Available images

Catalog No. ABIN2780649
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
4.8440056 ABIN2778065 WB Rabbit Middle Region Log in to see Polyclonal 1
4.8440056 ABIN2780650 WB Rabbit C-Term Log in to see Polyclonal 1
4.8440056 ABIN2461741 ELISA WB Rabbit Log in to see Polyclonal 0
4 ABIN202780 WB Rabbit IgG C-Term Log in to see Polyclonal 0
4 ABIN6742402 WB Rabbit AA 503-552 Log in to see Polyclonal 0

General

Antigen Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2) Antibodies
Epitope N-Term
(11), (10), (10), (8), (8), (6), (5), (5), (5), (4), (2), (2), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
(70), (15), (12), (8), (8), (8), (7), (6), (5), (5), (4), (3), (2), (2), (1), (1), (1)
Host Rabbit
(61), (12)
Clonality
Polyclonal
Conjugate Un-conjugated
(3), (3), (3), (2), (2), (2)
Application Western Blotting (WB)
(48), (29), (28), (21), (3), (2), (2), (1), (1), (1)
Pubmed 1 reference available
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Product details

Target Details Application Details Handling References Images
Blocking Peptide Blocking peptide for this product available: ABIN980874
Sequence YISSSSSASS HASCHSEGSE NSFQSSSSSV PSSPNSSNSD TNGNPKNGDL
Predicted Reactivity Cow: 79%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%
Characteristics This is a rabbit polyclonal antibody against NR1D2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human NR1D2

Target Details

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Antigen
Alternative Name NR1D2 (NR1D2 Antibody Abstract)
Background NR1D2 can interact with NCOA5 coactivator, leading to a strong increase of transcription of target genes. NR1D2 also binds to the sequences 5'-AATGTAGGTCA-3' and 5'-ATAACTAGGTCA-3' and acts as a potent competitive transcriptional silencer and negative regulator of RORalpha mediated trans-activation. NR1D2 may play different roles in metabolism, inflammation, and circadian cycling in the organ-specific manner in homeostasis.
Alias Symbols: BD73, EAR-1r, HZF2, Hs.37288, RVR, EAR-1R
Protein Interaction Partner: MID2, RBPMS, TRIM27, NOTCH2NL, KRTAP10-9, KRT40, KRTAP4-2, PRMT6, SKP1, UBC, SIN3B, KAT5, NCOR1, TAF9, TAF6, HDAC1, GTF2B, NCOA5, UBE2I, CUL1, NR1D1, RGN,
Protein Size: 579
Molecular Weight 65 kDa
Gene ID 9975
NCBI Accession NM_005126, NP_005117
UniProt Q14995
Pathways Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway

Application Details

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Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 579 AA

Restrictions For Research Use only

Handling

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Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References

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Background publications

Wang, Liu, Liu, Li, Song, Yuan, Li, Zhao, Lu: "The orphan nuclear receptor Rev-erbbeta recruits Tip60 and HDAC1 to regulate apolipoprotein CIII promoter." in: Biochimica et biophysica acta, Vol. 1783, Issue 2, pp. 224-36, 2008

Images

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Supplier Images
Western Blotting (WB) image for anti-Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2) (N-Term) antibody (ABIN2780649) WB Suggested Anti-NR1D2 Antibody Titration: 0.2-1 ug/ml Positive Control: Jurkat c...