anti-Human Nuclear Receptor Subfamily 1, Group H, Member 3 antibody for Chromatin Immunoprecipitation

Recommended Nuclear Receptor Subfamily 1, Group H, Member 3 Antibody

Antigen
Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) Antibodies
  • NR1H3
  • LXR-a
  • LXRA
  • RLD-1
  • AU018371
  • LXR
  • RLD1
  • Unr1
  • LXRalpha
  • LXR-alpha
  • im:7141239
  • wu:fd59b01
  • zgc:113339
  • zgc:158542
  • nuclear receptor subfamily 1 group H member 3
  • nuclear receptor subfamily 1, group H, member 3
  • NR1H3
  • nr1h3
  • Nr1h3
Epitope
N-Term
15
12
10
9
8
8
7
4
3
3
3
3
3
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
133
71
65
11
9
9
7
6
6
5
4
4
3
2
2
2
2
2
2
Host
Rabbit
122
15
6
Clonality
Polyclonal
Conjugate
Un-conjugated
7
5
5
2
2
2
2
2
2
2
2
2
2
2
Application
ChIP DNA-Sequencing (ChIP-seq), Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
119
58
26
15
9
8
8
6
4
3
1
1
1
1
Options

Available images

Catalog No. ABIN2668708
$ 519.17
Plus shipping costs $45.00 and $22.60 dry ice
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
1 ABIN2668055 ChIP-seq ChIP WB Rabbit IgG Polyclonal 0

General

Antigen Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) Antibodies
Epitope N-Term
(15), (12), (10), (9), (8), (8), (7), (4), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(133), (71), (65), (11), (9), (9), (7), (6), (6), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2)
Host Rabbit
(122), (15), (6)
Clonality
Polyclonal
Conjugate Un-conjugated
(7), (5), (5), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application ChIP DNA-Sequencing (ChIP-seq), Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
(119), (58), (26), (15), (9), (8), (8), (6), (4), (3), (1), (1), (1), (1)
Pubmed 1 reference available
Supplier

Product details

Target Details Application Details Handling References Images
Purification Affinity Purified
Immunogen This LXR-alpha antibody was raised against a peptide in the N-terminal region of human LXR-alpha.
Isotype IgG

Target Details

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Antigen
Alternative Name LXR-alpha (NR1H3 Antibody Abstract)
Background LXR-α (Liver X receptor alpha, NR1H3) is an orphan nuclear receptor and a member of the NR1 receptor family. The LXR receptors (including LXR-α and LXR-β) bind oxysterols and play key roles in maintaining cholesterol homeostasis in macrophages, primarily by regulating multiple components of the reverse cholesterol transport. They also are potent inhibitors of inflammation and are capable of repressing cytokine and chemokine production by Toll-like receptor (TLR)-activated macrophages. LXR-α is expressed mainly in liver and adipose tissue and interacts with RXR, shifting RXR to an active ligand- binding subunit mediating responses to retinoids.
Molecular Weight 52 kDa
Gene ID 10062
Pathways Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C

Application Details

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Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

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Format Liquid
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage -20 °C
Storage Comment Antibodies in solution can be stored at -20 °C for 2 years.
Expiry Date 6 months

References

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Product cited in:

Kemmerer, Wittig, Richter, Brüne, Namgaladze: "AMPK activates LXRα and ABCA1 expression in human macrophages." in: The international journal of biochemistry & cell biology, Vol. 78, pp. 1-9, 2016

Images

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Supplier Images
Chromatin Immunoprecipitation (ChIP) image for anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (N-Term) antibody (ABIN2668708) LXR-α antibody (pAb) tested by ChIP-chip. ChIP was performed using the ChIP-IT® High ...
Chromatin Immunoprecipitation (ChIP) image for anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (N-Term) antibody (ABIN2668708) LXR-α antibody (pAb) tested by ChIP. Chromatin immunoprecipitation (ChIP) was perform...
Western Blotting (WB) image for anti-Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (N-Term) antibody (ABIN2668708) LXR-α antibody (pAb) tested by Western blot. Whole cell extract of Hep G2 cells (30 µ...