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High TRA16 expression promotes small cell lung carcinoma by activating estrogen receptor beta and blocking testicular orphan nuclear receptor 2
TRA16 may function as a novel repressor to selectively suppress the TR4-mediated transactivation
Together, these findings provide the first in vivo evidence that an orphan nuclear receptor, such as TR4, may play major roles in the RA-mediated apoptosis or differentiation in P19 cells.
Taken together, these results suggested that TR4 should be one of important regulators of OXT gene expression.
May act as a repressor of nr2c2-mediated transactivation by suppressing the binding between nr2c2 and its response element in target genes (By similarity).
TR4 orphan receptor associated protein TRA16
, nuclear receptor 2C2-associated protein
, Nuclear receptor 2C2-associated protein
, TR4 orphan receptor-associated 16 kDa protein
, repressor for TR4 transactivation
, TR4 orphan receptor-associated 16 kDa protein homolog