anti-Mouse (Murine) NR4A2 antibody for Western Blotting

Recommended NR4A2 Antibody

Antigen
Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) Antibodies
  • nr41/42/43
  • Nr4a2
  • nurr1
  • not
  • rnr1
  • hzf-3
  • tinur
  • NGFI-B
  • HZF-3
  • NOT
  • NURR1
  • RNR1
  • TINUR
  • Nurr1
  • RNR-1
  • TINOR
  • ngf1b
  • nr4a2
  • zgc:92696
  • nuclear receptor subfamily 4 group A member 2
  • nuclear receptor
  • nuclear receptor subfamily 4, group A, member 2
  • nuclear receptor subfamily 4, group A, member 2b
  • NR4A2
  • nr41/42/43
  • nr4a2
  • Nr4a2
  • nr4a2b
Epitope
N-Term
9
7
5
4
3
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio)
70
22
18
5
5
4
4
4
4
3
2
2
2
2
2
1
1
Host
Rabbit
50
22
Clonality
Polyclonal
Conjugate
This NR4A2 antibody is un-conjugated
2
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
54
39
23
11
6
4
3
2
1
1
Options

Available images

Catalog No. ABIN2780752
$ 319.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
16.890335 ABIN3032065 IF IHC ELISA WB Rabbit Ig Fraction AA 13-42 Polyclonal 0
13.550937 ABIN6390088 ELISA WB Rabbit IgG AA 100-180 Polyclonal 0
13.550937 ABIN1574115 WB Rabbit IgG2b AA 310-360 Polyclonal 0
10 ABIN6745718 IHC IHC (p) WB Rabbit IgG N-Term Polyclonal 0
10 ABIN5537220 IF IHC (p) WB Rabbit Ig Fraction AA 13-42, N-Term Polyclonal 0
7.890334 ABIN2777552 WB Rabbit C-Term Polyclonal 1
4.890334 ABIN2780753 WB Rabbit Middle Region Polyclonal 1
4.890334 ABIN2460549 ELISA WB Rabbit Polyclonal 0
4.890334 ABIN2461779 ELISA WB Rabbit Polyclonal 0
4 ABIN6742800 WB Rabbit AA 503-552 Polyclonal 0
1 ABIN2626315 ICC IF WB Rabbit IgG AA 344-530 Polyclonal 0
1 ABIN2743332 ELISA WB Rabbit AA 164-197 Polyclonal 0
1 ABIN2963655 IHC ELISA WB Rabbit IgG Polyclonal 0
1 ABIN308640 IHC WB Rabbit IgG1 AA 513-526 Polyclonal 0
1 ABIN5558768 ELISA IHC IP WB Biotin Rabbit Polyclonal 0

General

Antigen Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) Antibodies
Epitope N-Term
(9), (7), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio)
(70), (22), (18), (5), (5), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (1), (1)
Host Rabbit
(50), (22)
Clonality
Polyclonal
Conjugate This NR4A2 antibody is un-conjugated
(2), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(54), (39), (23), (11), (6), (4), (3), (2), (1), (1)
Pubmed 2 references available
Supplier

Product Details anti-NR4A2 Antibody

Target Details NR4A2 Application Details Handling References for anti-NR4A2 antibody (ABIN2780752) Images
Blocking Peptide Blocking peptide for this product available: ABIN980928
Sequence MPCVQAQYGS SPQGASPASQ SYSYHSSGEY SSDFLTPEFV KFSMDLTNTE
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Characteristics This is a rabbit polyclonal antibody against NR4A2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human NR4A2
Plasmids, Primers & others

Target Details NR4A2

Product Details anti-NR4A2 Antibody Application Details Handling References for anti-NR4A2 antibody (ABIN2780752) Images back to top
Antigen
Alternative Name NR4A2 (NR4A2 Antibody Abstract)
Background NR4A2 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. The protein may act as a transcription factor. Mutations in NR4A2 gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of NR4A2 gene may be associated with rheumatoid arthritis.This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Four transcript variants encoding four distinct isoforms have been identified for this gene. Additional alternate splice variants may exist, but their full length nature has not been determined.This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HZF-3, NOT, NURR1, RNR1, TINUR
Protein Interaction Partner: CDKN2D, TCEAL5, BAZ1B, ELAVL1, COPS5, RXRB, RXRA, RUNX1, SMARCA4, SMARCA2, SIN3A, NCOR2, SFPQ, PIAS4, RPS6KA1, CDKN1C, RARB, RARA, CREB1,
Protein Size: 598
Molecular Weight 66 kDa
Gene ID 4929
NCBI Accession NM_006186, NP_006177
UniProt P43354
Pathways Nuclear Receptor Transcription Pathway, Dopaminergic Neurogenesis, Steroid Hormone Mediated Signaling Pathway

Application Details

Product Details anti-NR4A2 Antibody Target Details NR4A2 Handling References for anti-NR4A2 antibody (ABIN2780752) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 598 AA

Restrictions For Research Use only

Handling

Product Details anti-NR4A2 Antibody Target Details NR4A2 Application Details References for anti-NR4A2 antibody (ABIN2780752) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-NR4A2 antibody (ABIN2780752)

Product Details anti-NR4A2 Antibody Target Details NR4A2 Application Details Handling Images back to top
Product cited in:

Brami-Cherrier, Anzalone, Ramos, Forne, Macciardi, Imhof, Borrelli: "Epigenetic reprogramming of cortical neurons through alteration of dopaminergic circuits." in: Molecular psychiatry, Vol. 19, Issue 11, pp. 1193-200, 2014

Background publications

Smith, Luk, Newton, Roberts, Sturm, Muscat: "Melanocortin-1 receptor signaling markedly induces the expression of the NR4A nuclear receptor subgroup in melanocytic cells." in: The Journal of biological chemistry, Vol. 283, Issue 18, pp. 12564-70, 2008

Images

Product Details anti-NR4A2 Antibody Target Details NR4A2 Application Details Handling References for anti-NR4A2 antibody (ABIN2780752) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (N-Term) antibody (ABIN2780752) Immunohistochemistry of formalin-fixed, paraffin-embedded human adrenal tissue after ...
Immunohistochemistry (IHC) image for anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (N-Term) antibody (ABIN2780752) Immunohistochemistry of formalin-fixed, paraffin-embedded human kidney tissue after h...
Western Blotting (WB) image for anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (N-Term) antibody (ABIN2780752) Lanes : Lane 1: Nuclear fraction from mouse substantia nigra Lane 2: Nuclear fraction...
Western Blotting (WB) image for anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (N-Term) antibody (ABIN2780752) WB Suggested Anti-NR4A2 Antibody Titration: 1 ug/ml Positive Control: Hela cell lysate